Results 101 to 110 of about 2,720,283 (280)

TiDeTree: a Bayesian phylogenetic framework to estimate single-cell trees and population dynamic parameters from genetic lineage tracing data. [PDF]

Proc Biol Sci, 2022
Seidel S, Stadler T.
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Correction to: 'TiDeTree: a Bayesian phylogenetic framework to estimate single-cell trees and population dynamic parameters from genetic lineage tracing data' (2022) by Seidel & Stadler. [PDF]

Proc Biol Sci, 2023
Seidel S, Stadler T.
europepmc   +1 more source

Demographic Change and Demand for Food in Australia [PDF]

The analysis of global population forecasts of the past 30 years by the US National Academy of Sciences confirms that errors have been considerable and that population forecasts have generally been upward-biased.
Qun Shi, Rod Tyers, Ron Duncan
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Bioecologia da broca-do-café, Hypothenemus hampei (Ferrari, 1867) (Coleoptera: Scolytidae), no agroecossistema cafeeiro do cerrado de Minas Gerais Bioecology of the coffee berry borer Hypothenemus hampei (Ferrari, 1867) (Coleoptera: Scolytidae) in a cerrado agrossistem of Cerrado in Minas Gerais State

Ciência e Agrotecnologia, 2003
Objetivou-se com este trabalho estudar aspectos da bioecologia da broca-do-café nas condições de cerrado do estado de Minas Gerais. Os levantamentos foram realizados em três propriedades cafeeiras nos municípios de Patrocínio e Carmo do Paranaíba, MG ...
Antônio José Ferreira, Júlio César Miranda, Vanda Helena Paes Bueno, Carvalho Carlos Ecole, Geraldo Andrade Carvalho   +4 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Range extension of the threatened Red Crossbill (Loxia curvirostra percna) in Canada: new insights from Anticosti Island, Québec

Avian Conservation and Ecology, 2018
Red Crossbill (Loxia curvirostra percna; e.g., Type 8) is considered a distinctive taxonomic group likely restricted to the island of Newfoundland. Although it has been speculated that the percna subspecies may be extinct, recent works continue to show ...
Junior A. Tremblay, Michel Robert, Douglas P. Hynes, Matthew A. Young, Bruno Drolet   +4 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Economical Evaluation of Reduced Herbicide Doses Application Rates to Control Phalaris brachystachys (Short-Spiked Canary Grass) in a Biennial Wheat–Sunflower Rotation in Mediterranean Dryland: A Modelling Approach

Plants
Phalaris brachystachys (short-spiked canary grass) is considered to be among the most troublesome cereal weeds in Mediterranean areas. A bioeconomic model, based on population dynamics, competition and economic sub-models, was developed to simulate the ...
Casto Zambrano-Navea, Fernando Bastida, Maria J. Aguilera, Jose L. Gonzalez-Andujar   +3 more
doaj   +1 more source