Results 111 to 120 of about 8,576,155 (303)
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
On the momentum of population growth [PDF]
For more about the East-West Center, see http://www.eastwestcenter.org/This paper develops a simple formula for making the calculation of momentum, and so shows the five parameters of the present condition that determine the ultimate population under the
Keyfitz, Nathan +1 more
core +1 more source
Morphology of Peripheral Blood Cells from Various Species of Turkish Herpetofauna
In this study, measurements of morphological and size parameters of peripheral blood cells (erythrocyte, leucocyte, thrombocyte) on blood smear preparation devices stained with Wright’s stain were given for 87 species from Turkish herpetofauna (19 ...
Hüseyin ARIKAN, Kerim CICEK
doaj +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Video: Population Council 70th Anniversary
For 70 years, the Population Council has transformed global thinking on critical health and development issues through our social science, public health, and biomedical research.
Population Council
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New Zealand regions, 1986-2001: Dependency and development of social capital [PDF]
The development of social capital is significantly affected by benefit dependency of the population. This paper investigates measures of social cohesion and measures of dependency on society across the regions of New Zealand.
Lindop, J. +3 more
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Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Short, stringent lockdowns halted SARS-CoV-2 transmissions in Danish municipalities
In late 2020, the focus of the global effort against the COVID-19 pandemic centered around the development of a vaccine, when reports of a mutated SARS-CoV-2 virus variant in a population of 17 million farmed mink came from Denmark, threatening to ...
Florian Ege
doaj +1 more source
General Dynamics Corporation Report GA-1612
From preface: This report presents the status of design of the MGCR prototype plant as of July 1 ...
General Dynamics Corporation
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