Results 101 to 110 of about 2,912,298 (341)

Convergence of generalized urn models to non-equilibrium attractors

open access: yes, 2014
Generalized Polya urn models have been used to model the establishment dynamics of a small founding population consisting of k different genotypes or strategies.
Faure, Mathieu, Schreiber, Sebastian
core   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Spatiotemporal profiling reveals the impact of caloric restriction in the aging mammalian brain

open access: yesCell Reports
Summary: Caloric restriction (CR) is a well-studied intervention that extends lifespan and slows cognitive decline across species, yet the specific cell populations and molecular pathways involved remain elusive. In this study, we profiled >500,000 cells
Zehao Zhang   +6 more
doaj   +1 more source

Protective sexual behaviours among young adults in Nigeria: influence of family support and living with both parents

open access: yesBMC Public Health, 2019
Background Many studies have focused on risky sexual behaviour among adolescents and young adults; however, literature on protective sexual practices among this age cohort is still evolving.
Anthony Idowu Ajayi   +1 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Visualizing population dynamics of alaska\u27s arctic communities [PDF]

open access: yes, 2009
Arctic demography has previously been reviewed on a large scale, across the circumpolar nations. We look instead at some recent population dynamics on sub-regional to community scales, focusing on Arctic Alaska.
Hamilton, Lawrence C., Mitiguy, Angela M
core   +1 more source

Modelling the Dynamics of an Aedes albopictus Population

open access: yes, 2010
We present a methodology for modelling population dynamics with formal means of computer science. This allows unambiguous description of systems and application of analysis tools such as simulators and model checkers.
Andrea Maggiolo-Schettini   +31 more
core   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Ageing populations: new challenges in longevity

open access: yesBMC Public Health
Background High-income countries experienced unprecedented gains in life expectancy throughout the twentieth century. However, recent evidence suggests that these gains have slowed, especially at older ages.
Julia Callaway   +5 more
doaj   +1 more source

Challenges in the case-based surveillance of infectious diseases

open access: yesRoyal Society Open Science
To effectively inform infectious disease control strategies, accurate knowledge of the pathogen’s transmission dynamics is required. Since the timings of infections are rarely known, estimates of the infection incidence, which is crucial for ...
Oliver Eales   +2 more
doaj   +1 more source

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