Results 81 to 90 of about 734,655 (246)

Mobility and Population Dynamics

open access: yes, 2007
Contains fulltext : 160919.pdf (Publisher’s version ) (Open Access)
Smith, L., Hebinck, P.G.M.
openaire   +2 more sources

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Association between the number of comorbidities and all-cause mortality during the COVID-19 pandemic: A Danish nationwide, retrospective cohort study

open access: yesJournal of Public Health Research
Objectives: Chronic illnesses have been linked to elevated risks of hospitalization and mortality during the COVID 19 pandemic. While many studies have examined how specific comorbidities influence outcomes among hospitalized COVID 19 patients, less is ...
Virginia Zarulli   +2 more
doaj   +1 more source

RANDOM EVOLUTION IN POPULATION DYNAMICS

open access: yesInternational Journal of Bifurcation and Chaos, 2010
We present a perturbative formalism to deal with linear random positive maps. We generalize the biological concept of the population growth rate when a Leslie matrix has random elements (i.e. characterizing the macroscopic disorder in the vital parameters).
openaire   +2 more sources

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Morphology of Peripheral Blood Cells from Various Species of Turkish Herpetofauna

open access: yesActa Herpetologica, 2010
In this study, measurements of morphological and size parameters of peripheral blood cells (erythrocyte, leucocyte, thrombocyte) on blood smear preparation devices stained with Wright’s stain were given for 87 species from Turkish herpetofauna (19 ...
Hüseyin ARIKAN, Kerim CICEK
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Factors associated with consistent condom use: a cross-sectional survey of two Nigerian universities

open access: yesBMC Public Health, 2019
Background Consistent condom use is central to the prevention of transmission of human immunodeficiency virus (HIV) and other sexually transmitted diseases (STDs), especially among young adults.
Anthony Idowu Ajayi   +2 more
doaj   +1 more source

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