Results 51 to 60 of about 2,848,057 (332)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Socioeconomic inequalities in survival to retirement age in Denmark: a register-based analysis

Genus
Around the world, people are increasingly living to older ages. This challenges the sustainability of the pension systems. In Denmark, statutory retirement age increases gradually to account for changes in life expectancy.
Cosmo Strozza, Serena Vigezzi, Julia Callaway, Aleksandrs Aleksandrovs, Ilya Kashnitsky   +4 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

Photosynthesis under far‐red light—evolutionary adaptations and bioengineering of light‐harvesting complexes

FEBS Letters, EarlyView.
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii, Edoardo Andrea Cutolo, Daniele Montepietra, Claudia Battarra, Roberto Caferri, Stefano Capaldi, Zeno Guardini, Luca Dall'Osto, Roberto Bassi   +8 more
wiley   +1 more source

Life history predicts global population responses to the weather in terrestrial mammals

eLife, 2022
With the looming threat of abrupt ecological disruption due to a changing climate, predicting which species are most vulnerable to environmental change is critical.
John Jackson, Christie Le Coeur, Owen Jones   +2 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Landscape analysis of the Kenyan policy on the treatment and prevention of diarrheal disease among under-5 children

BMJ Open
Objective Diarrhoea remains a leading cause of morbidity and death among under-5 children in Kenya, despite multipronged policy and programme initiatives to increase access to treatment. This study interrogates the comprehensiveness and adequacy of Kenya’
Blessing Mberu, Kelly K Baker, Sheillah Simiyu, Daniel Sewell, Fanta D Gutema, Innocent K Tumwebaze, Phylis J Busienei   +6 more
doaj   +1 more source

Asymptotic properties of stochastic population dynamics [PDF]

, 2008
In this paper we stochastically perturb the classical Lotka{Volterra model x_ (t) = diag(x1(t); ; xn(t))[b + Ax(t)] into the stochastic dierential equation dx(t) = diag(x1(t); ; xn(t))[(b + Ax(t))dt + dw(t)]: The main aim is to study the asymptotic ...
Deng, Feiqi, EPSRC (U.K.) (Funder), Jinan University of China (Funder), Key Programs of Science and Technology of Guangzhou (Funder), Mao, Xuerong, National Natural Science Foundation of China (Funder), Pang, Sulin   +6 more
core  

Emergence and Growth of Complex Networks in Adaptive Systems [PDF]

, 1998
We consider the population dynamics of a set of species whose network of catalytic interactions is described by a directed graph. The relationship between the attractors of this dynamics and the underlying graph theoretic structures like cycles and ...
Jain, Sanjay, Krishna, Sandeep
core   +3 more sources