Results 61 to 70 of about 9,041,918 (353)

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Prevalence and correlates of sexual violence among adolescent girls and young women: findings from a cross-sectional study in a South African university

BMC Women's Health, 2021
Background Epidemiological data on the prevalence and factors associated with sexual violence is critical to understanding the magnitude of the problem and designing effective interventions.
Anthony Idowu Ajayi, Elmon Mudefi, Eyitayo Omolara Owolabi   +2 more
doaj   +1 more source

Population dynamics of the Taimyr reindeer population

Rangifer, 1996
The Taimyr herd of wild reindeer (Rangifer tarandus tarandus L.) is one of the three largest herds of wild Rangifer in the world, and numbered about 600 000 in 1993. The herd grew continuously from 1959 to 1990, and is now stable due primarily to intensive commercial harvesting along the Khatanga River. Meat from the commercial harvest is processed and
Pavlov, B.M., Kolpashchikov, L.A., Zyryanov, V.A.   +2 more
openaire   +5 more sources

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Landscape analysis of the Kenyan policy on the treatment and prevention of diarrheal disease among under-5 children

BMJ Open
Objective Diarrhoea remains a leading cause of morbidity and death among under-5 children in Kenya, despite multipronged policy and programme initiatives to increase access to treatment. This study interrogates the comprehensiveness and adequacy of Kenya’
Blessing Mberu, Kelly K Baker, Sheillah Simiyu, Daniel Sewell, Fanta D Gutema, Innocent K Tumwebaze, Phylis J Busienei   +6 more
doaj   +1 more source

Cost-effectiveness of inhaled oxytocin for prevention of postpartum haemorrhage: a modelling study applied to two high burden settings

BMC Medicine, 2020
Background Access to oxytocin for prevention of postpartum haemorrhage (PPH) in resource-poor settings is limited by the requirement for a consistent cold chain and for a skilled attendant to administer the injection.
Natalie Carvalho, Mohammad Enamul Hoque, Victoria L. Oliver, Abbey Byrne, Michelle Kermode, Pete Lambert, Michelle P. McIntosh, Alison Morgan   +7 more
doaj   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Incidence rates in dynamic populations [PDF]

International Journal of Epidemiology, 2012
The purpose of the present article is to explain the calculation of incidence rates in dynamic populations with the use of simple mathematical and statistical concepts. The first part will consider incidence rates in dynamic populations, and how they can best be taught in basic, intermediate and advanced courses.
Vandenbroucke, J.P., Pearce, N.
openaire   +5 more sources

Modelling the influence of temperature and rainfall on the population dynamics of Anopheles arabiensis

Malaria Journal, 2016
Malaria continues to be one of the most devastating diseases in the world, killing more humans than any other infectious disease. Malaria parasites are entirely dependent on Anopheles mosquitoes for transmission.
G. Abiodun, R. Maharaj, P. Witbooi, K. Okosun   +3 more
semanticscholar   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source