Results 61 to 70 of about 2,079,774 (295)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Dynamics of populations with changing rates: Generalization of the stable population theory

Theoretical Population Biology, 1987
A general and complete exposition of the dynamics of populations with changing vital rates is given in the discrete time formulation. Results obtained are stronger than Lopez's or Hajnal's. In addition to the proof of existence of limits, an explicit expression for the age distribution is obtained by considering forward products of population ...
openaire   +3 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

The Relativistic Factor in the Orbital Dynamics of Point Masses

, 2008
There is a growing population of relativistically relevant minor bodies in the Solar System and a growing population of massive extrasolar planets with orbits very close to the central star where relativistic effects should have some signature.
A. Einstein, B. Shahid-Saless, E.V. Pitjeva, F. Marzari, F. Varadi, F.C. Adams, Federico Benitez, G. Sitarski, I. Ciufolini, I.I. Shapiro, J. Laskar, J. Laskar, J.A. Fernandez, J.D. Anderson, J.E. Chambers, K. Gozdziewski, L. Iorio, M. Nagasawa, M. Soffel, M.J. Duncan, P. Michel, P. Michel, P. Saha, P.S. Lykawka, R. Barnes, R. Gomes, R.A. Mardling, S. Ferraz-Mello, S. Kopeikin, S. Kopeikin, S. Pireaux, S.A. Klioner, T. Damour, T. Damour, T. Damour, T. Gallardo, T. Quinn, T.A. Michtchenko, Tabaré Gallardo, V. Brumberg, V. Brumberg, X.X. Newhall   +41 more
core   +1 more source

Spinal interneuron population dynamics underlying flexible pattern generation

Nature Communications
AbstractThe mammalian spinal locomotor network is composed of diverse populations of interneurons that collectively orchestrate and execute a range of locomotor behaviors. Despite the identification of many classes of spinal interneurons constituting the locomotor network, it remains unclear how the network’s collective activity computes and modifies ...
Lahiru N. Wimalasena, Chethan Pandarinath, Nicholas AuYong   +2 more
openaire   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Non-linear analysis indicates chaotic dynamics and reduced resilience in model-based Daphnia populations exposed to environmental stress. [PDF]

PLoS ONE, 2014
In this study we present evidence that anthropogenic stressors can reduce the resilience of age-structured populations. Enhancement of disturbance in a model-based Daphnia population lead to a repression of chaotic population dynamics at the same time ...
Richard Ottermanns, Kerstin Szonn, Thomas G Preuβ, Martina Roβ-Nickoll   +3 more
doaj   +1 more source

Daphnias: from the individual based model to the large population equation [PDF]

, 2012
The class of deterministic 'Daphnia' models treated by Diekmann et al. (J Math Biol 61: 277-318, 2010) has a long history going back to Nisbet and Gurney (Theor Pop Biol 23: 114-135, 1983) and Diekmann et al. (Nieuw Archief voor Wiskunde 4: 82-109, 1984).
A Joffe, A Roos de, J Jacod, J. A. J. Metz, JAJ Metz, K Oelschläger, M Durinx, N Fournier, O Diekmann, O Diekmann, O Diekmann, O Diekmann, O Diekmann, O Diekmann, P Jagers, RM Nisbet, S Méléard, S Méléard, TG Kurtz, VC Tran, Viet Chi Tran, WSC Gurney   +21 more
core   +4 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source