Results 71 to 80 of about 2,079,774 (295)

Structural and Dynamic Analysis of the Human Capital Health Component of the Socio-Economic System

Статистика и экономика, 2021
Purpose of the research. Human capital in the modern world is the primary factor in ensuring the progressive development of society. The most important component of human capital is the component of health, which affects the quality of labor resources ...
K. Ketova, D. D. Vavilova
doaj   +1 more source

On Synchronization in a Lattice Model of Pulse-Coupled Oscillators

, 1995
We analyze the collective behavior of a lattice model of pulse-coupled oscillators. By means of computer simulations we find the relation between the intrinsic dynamics of each member of the population and their mutual interaction that ensures, in a ...
A. Corral, A.A. Middleton, A.T. Winfree, A.V.M. Herz, Albert Díaz-Guilera, Alex Arenas, C. Torras, C. Vanvreeswijk, C. Vanvreeswijk, C.C. Chen, C.S. Peskin, Conrad J. Pérez, G.B. Ermentrout, H.J.S. Feder, J.J. Hopfield, J.J. Hopfield, J.P. Keener, J.P. Segundo, M. Tsodyks, N. Ikeda, P. Bak, Q. Zhilin, R.E. Mirollo, S. Bottani, S.H. Strogatz, U. Ernst, W. Gerstner, Y. Kuramoto, Álvaro Corral   +28 more
core   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Game Theoretic Approach to the Stabilization of Heterogeneous Multiagent Systems Using Subsidy

, 2013
We consider a multiagent system consisting of selfish and heterogeneous agents. Its behavior is modeled by multipopulation replicator dynamics, where payoff functions of populations are different from each other.
Kanazawa, Takafumi, Morimoto, Takuya, Ushio, Toshimitsu   +2 more
core   +1 more source

Abstraction of Markov Population Dynamics via Generative Adversarial Nets

, 2021
Markov Population Models are a widespread formalism used to model the dynamics of complex systems, with applications in Systems Biology and many other fields. The associated Markov stochastic process in continuous time is often analyzed by simulation, which can be costly for large or stiff systems, particularly when a massive number of simulations has ...
Cairoli F., Carbone G., Bortolussi L.
openaire   +3 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

FISH POPULATION AS A DYNAMIC SYSTEM WITH ELEMENTS OF SELF-REGULATION

Юг России: экология, развитие, 2014
The study of fish population dynamics at system approach is most appropriate enabling consideration of processes affecting population abundance and structure and investigation of processes of stock composition and abundance regulation, fishery management.
G. A. Sudakov
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Social Dynamics of Gang Involvement: A Mathematical Approach [PDF]

, 2012
Gangs have played a significant role in the social and political history of the United States, and continue to impact the country today, as gang violence and participation rates continue to grow. In this paper, we explore the dynamics of gang involvement
Austin, Joshua, Sanchez, Fabio, Smith, Emily, Srinivasan, Sowmya   +3 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source