Results 91 to 100 of about 7,668,561 (373)
Faster model-based estimation of ancestry proportions
Peer Community JournalAncestry estimation from genotype data in unrelated individuals has become an essential tool in population and medical genetics to understand demographic population histories and to model or correct for population structure.
Santander, Cindy G. +2 more
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Exploring a Pool‐seq‐only approach for gaining population genomic insights in nonmodel species
Ecology and Evolution, 2019 Developing genomic insights is challenging in nonmodel species for which resources are often scarce and prohibitively costly. Here, we explore the potential of a recently established approach using Pool‐seq data to generate a de novo genome assembly for ...
Sara Kurland +9 more
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Population genetics models of local ancestry
, 2012 Migrations have played an important role in shaping the genetic diversity of human populations. Understanding genomic data thus requires careful modeling of historical gene flow.
Falush, Li, Simon Gravel
core +1 more source
Admixture Correction in the Outgroup-f3 Statistic [PDF]
, 2018 Genetic inheritance can be studied within a purely genetic scope. However, this eliminates part of the picture. The field of genetics is often thought of as a natural science with little in common with fields of social science. However, in human genetics
Tunga, Nita
core +1 more source
SNP barcodes provide higher resolution than microsatellite markers to measure Plasmodium vivax population genetics [PDF]
, 2020 Abebe A. Fola +11 more
openalex +1 more source
Population genetics of Lithuanians
Annals of Human Biology, 2001 The primary objective of this article was to overview the present-day knowledge on genetic features of the Lithuanian population. Genetic differentiation within the Lithuanian population and the relationship between Lithuanians and other European populations was analysed by means of blood groups, serum protein polymorphisms and DNA markers including ...
openaire +2 more sources
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Singular solutions of the diffusion equation of population genetics [PDF]
, 2007 The forward diffusion equation for gene frequency dynamics is solved subject to the condition that the total probability is conserved at all times. This can lead to solutions developing singular spikes (Dirac delta functions) at the gene frequencies 0 ...
A.J. McKane +19 more
core +2 more sources
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Nature CommunicationsIncomplete penetrance, or absence of disease phenotype in an individual with a disease-associated variant, is a major challenge in variant interpretation.
Sanna Gudmundsson +11 more
doaj +1 more source