Results 161 to 170 of about 7,668,561 (373)

Population genetics-informed meta-analysis in seven genes associated with risk to dengue fever disease

, 2018
Marisa Oliveira, Diana P. Saraiva, Bruno Cavadas, Verónica Fernandes, Nicole Pedro, Isabelle Casadémont, Fanny Koeth, Farida Alshamali, Nourdin Harich, Lotfi Cherni, Beatríz Sierra, María G. Guzmán, Anavaj Sakuntabhai, Luı́sa Pereira   +13 more
openalex   +2 more sources

Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins

FEBS Open Bio, EarlyView.
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó, Eszter Nagy‐Kanta, Soma Varga, Edit Andrea Jáger, Csaba István Pongor, Mária Laki, András József Laki, Zoltán Gáspári   +7 more
wiley   +1 more source

The apolipoprotein multigene family: biosynthesis, structure, structure-function relationships, and evolution.

Journal of Lipid Research, 1988
W H Li, M Tanimura, C C Luo, S Datta, L Chan   +4 more
doaj   +1 more source

Population Genetics Data of 21 Autosomal STR Loci in the Romanian Population

Data
This study aimed to determine the allele frequencies and genetic diversity of 21 autosomal short tandem repeat (STR) loci from the Expanded U.S. Core Loci and European Standard Set in the Romanian population. A random sample of 928 unrelated men from all
George Popoiu, Florin Stanciu, Veronica Cuțăr, Simona Vladu, Paulina Podgoreanu, Violeta Nicola, Ionel Marius Stoian, Anastasia Procopciuc, Bogdan Hațegan, Bogdan Negoiță, Alis Mihaela Păunache, Adnana Cotolea, Ana Rădulescu, Adrian Constantin Hubca, Sergiu Emil Georgescu   +14 more
doaj   +1 more source

Establishment and optimization of the two‐step induction system for generating primordial germ cell‐like cells from chicken embryonic stem cells

FEBS Open Bio, EarlyView.
This study optimizes a two‐step induction system to generate PGCLCs from chicken ESCs. The induced cells express germline markers and migrate to gonads in ovo, offering a novel approach for avian genetic resource conservation. Primordial germ cells (PGCs) are the progenitor cells of sperm and eggs.
Zeyu Li, XianShuai Xu, GuangZheng Liu, XiaoQian Lv, JiuZhou Song, HongYan Sun, YingJie Niu, QiSheng Zuo, Wei Han, BiChun Li, Kai Jin   +10 more
wiley   +1 more source

The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells

FEBS Open Bio, EarlyView.
We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel, Mekala Gunasekaran, Audrey L. Daugherty, Natalya M. Wells, Johnnie Turner, Christine C. Bruels, Christina A. Pacak, Isabelle Draper, Peter B. Kang   +8 more
wiley   +1 more source

Algorithms for the identification of prevalent diabetes in the All of Us Research Program validated using polygenic scores

Scientific Reports
The All of Us Research Program (AoU) is an initiative designed to gather a comprehensive and diverse dataset from at least one million individuals across the USA.
Lukasz Szczerbinski, Ravi Mandla, Philip Schroeder, Bianca C. Porneala, Josephine H. Li, Jose C. Florez, Josep M. Mercader, Miriam S. Udler, Alisa K. Manning   +8 more
doaj   +1 more source

On the importance of skewed offspring distributions and background selection in viral population genetics [PDF]

, 2016
Kristen K. Irwin, Stefan Laurent, Sebastian Matuszewski, Séverine Vuilleumier, Louise Ormond, Hyunjin Shim, Claudia Bank, Jeffrey D. Jensen   +7 more
openalex   +1 more source

pegas: an R package for population genetics with an integrated-modular approach

Bioinform., 2010
E. Paradis
semanticscholar   +1 more source

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

FEBS Open Bio, EarlyView.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui, Maryline Santerre, Natalia Shcherbik, Bassel E Sawaya   +3 more
wiley   +1 more source