Results 161 to 170 of about 1,325,954 (330)

POPULATION GENETICS [PDF]

, 1969
Leigh Van Valen
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

GENETICS OF NATURAL POPULATIONS. XL. HETEROTIC AND DELETERIOUS EFFECTS OF RECESSIVE LETHALS IN POPULATIONS OF DROSOPHILA PSEUDOOBSCURA

, 1968
Theodosius Dobzhansky, B Spassky
openalex   +2 more sources

POPULATION GENETICS OF ALLOZYME VARIATION IN NEUROSPORA INTERMEDIA [PDF]

, 1975
Philip T. Spieth
openalex   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

The population genetics of parthenogenetic strains of Drosophila mercatorum [PDF]

, 1973
Alan R. Templeton, Edward D. Rothman
openalex   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

GENETICS OF NATURAL POPULATIONS. XXVIII. THE MAGNITUDE OF THE GENETIC LOAD IN POPULATIONS OF DROSOPHILA PSEUDOOBSCURA

, 1960
B Spassky, N Spassky, Olga Pavlovsky, M G Krimbas, Costas B. Krimbas, Th. Dobzhansky   +5 more
openalex   +2 more sources

Population Genetics of Mexican Drosophila: I. Chromosomal variation in natural populations of Drosophila pseudoobscura from Central Mexico [PDF]

, 1975
Th. Dobzhansky, Rute C. Félix, J. Gúzman, Louis Levine, O. Olvera, Jeffery R. Powell, Rosa Miró, Víctor Salceda   +7 more
openalex   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source