Results 51 to 60 of about 1,325,954 (330)

Interplay between pleiotropy and secondary selection determines rise and fall of mutators in stress response [PDF]

, 2009
Dramatic rise of mutators has been found to accompany adaptation of bacteria in response to many kinds of stress. Two views on the evolutionary origin of this phenomenon emerged: the pleiotropic hypothesis positing that it is a byproduct of environmental
A Giraud, A Sali, AC Shaver, B Li, CS Wylie, DK Klimov, E Dekel, E Denamur, E Denamur, E Shakhnovich, E Shakhnovich, EI Shakhnovich, EI Shakhnovich, EJ Deeds, ES Slechta, Eugene I. Shakhnovich, F Taddei, G Feng, GM Suel, HC Tsui, I Bjedov, I Matic, IN Berezovsky, JAGM de Visser, JB Andre, JD Bloom, JM Raser, JW Drake, KB Zeldovich, KB Zeldovich, KB Zeldovich, KK Yan, KL Huisinga, KP Bjornson, L Lopez-Maury, M Heo, M Wrande, MB Elowitz, MJ Schofield, ML Mendillo, Muyoung Heo, N Rosenfeld, O Tenaillon, O Tenaillon, PD Sniegowski, PD Sniegowski, PJ Gerrish, PL Foster, R Du, RE Lenski, RR Iyer, RS Galhardo, RS Harris, Rustom Antia, S Maslov, S Miyazawa, WA Rosche, WJ Blake   +57 more
core   +5 more sources

Infection Models for Pine Wilt Disease on the Basis of Vector Behaviors

Population Ecology, EarlyView.
Infection models for pine wilt disease without vector density were built to estimate the transmission coefficient of the pathogenic nematode. The models successfully simulated the annual change in the density of infected trees for four pine stands. ABSTRACT Pine wilt disease is caused by the pinewood nematode (Bursaphelenchus xylophilus Steiner et ...
Katsumi Togashi
wiley   +1 more source

Population genetic characteristics of Hainan medaka with whole-genome resequencing

Frontiers in Genetics, 2022
The DMY gene is deleted in all males of the Sanya population (SY-medaka) of the Hainan medaka, Oryzias curvinotus, as recently reported by us. However, due to limited knowledge regarding their population genetic background, it is difficult to explore the
Zebin Yao, Shuisheng Long, Chun Wang, Chengqin Huang, Hairui Zhang, Liao Jian, Jingru Huang, Yusong Guo, Yusong Guo, Yusong Guo, Zhongdian Dong, Zhongdian Dong, Zhongdian Dong, Zhongduo Wang, Zhongduo Wang, Zhongduo Wang   +15 more
doaj   +1 more source

Speciation Through the Lens of Population Dynamics: A Theoretical Primer on How Small and Large Populations Diverge

Population Ecology, EarlyView.
Population size and dynamics fundamentally shape speciation by influencing genetic drift, founder events, and adaptive potential. Small populations may speciate rapidly due to stronger drift, whereas large populations harbor more genetic diversity, which can alter divergence trajectories. We highlight theoretical models that incorporate population size
Ryo Yamaguchi, Hidaka Kubo, Tokuya Ogawa, Hayate Omura   +3 more
wiley   +1 more source

Population genetics and GWAS: A primer. [PDF]

PLoS Biology, 2018
This primer provides some background to help non-specialists understand a new theoretical evolutionary genetics study that helps explain why thousands of variants of small effect contribute to complex traits.
Greg Gibson
doaj   +1 more source

Population genetics of translational robustness

, 2006
Recent work has shown that expression level is the main predictor of a gene’s evolutionary rate, and that more highly expressed genes evolve slower.
Drummond, D. Allan, Wilke, Claus O.
core   +2 more sources

FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz   +3 more
wiley   +1 more source

Demographic history and genomics of local adaptation in blue tit populations

Evolutionary Applications, 2020
Understanding the genomic processes underlying local adaptation is a central aim of modern evolutionary biology. This task requires identifying footprints of local selection but also estimating spatio‐temporal variations in population demography and ...
Charles Perrier, Quentin Rougemont, Anne Charmantier   +2 more
doaj   +1 more source

Bayesian computation via empirical likelihood

, 2012
Approximate Bayesian computation (ABC) has become an essential tool for the analysis of complex stochastic models when the likelihood function is numerically unavailable.
Beaumont, Chan, Christian P. Robert, Estoup, Fearnhead, Hudson, Kerrie L. Mengersen, Kim, Lopes, McVean, Ohta, Pierre Pudlo, Pritchard, Tavaré, Wilson   +14 more
core   +4 more sources

Growth, competition and cooperation in spatial population genetics [PDF]

, 2012
We study an individual based model describing competition in space between two different alleles. Although the model is similar in spirit to classic models of spatial population genetics such as the stepping stone model, here however space is continuous ...
Allstadt, Barton, Benzi, Berti, Birch, Cencini, Crow, D.R. Nelson, Doering, D’Ovidio, F. Toschi, Fisher, Frey, Gardiner, Hallatschek, Hernandez-Garcia, Kimura, Kimura, Kolmogorov, Korolev, Korolev, Korolev, Law, M.H. Jensen, Neufeld, Neuhauser, Odor, O’Malley, O’Malley, P. Perlekar, Perlekar, Perlekar, Pigolotti, Pringle, R. Benzi, Risken, S. Pigolotti, Smith, Tel, Vlad, Wright   +40 more
core   +3 more sources