Results 61 to 70 of about 7,445,333 (411)
The opportunities and challenges of integrating population histories into genetic studies of diverse populations: a motivating example from Native Hawaiians [PDF]
Front. Genet., 27 September 2021, 2020 There is an urgent and well-recognized need to extend genetic studies to diverse populations, but several obstacles continue to be prohibitive, including (but not limited to) the difficulty of recruiting individuals from diverse populations in large numbers and the lack of representation in available genomic references. These obstacles notwithstanding,
arxiv +1 more source
Population genetics in compressible flows
, 2011 We study competition between two biological species advected by a compressible velocity field. Individuals are treated as discrete Lagrangian particles that reproduce or die in a density-dependent fashion.
A. Kolmogorov +10 more
core +1 more source
Ancestral population genomics [PDF]
, 2012 The full genomes of several closely related species are now available, opening an emerging field of investigation borrowing both from population genetics and phylogenetics.
Dutheil, J., Hobolth, A.
core +2 more sources
Human genetic admixture through the lens of population genomics [PDF]
arXiv, 2021 Over the last fifty years, geneticists have made great strides in understanding how our species' evolutionary history gave rise to current patterns of human genetic diversity classically summarized by Lewontin in his 1972 paper, 'The Apportionment of Human Diversity'.
arxiv
Dismantling a dogma: the inflated significance of neutral genetic diversity in conservation genetics [PDF]
, 2020 The current rate of species extinction is rapidly approaching unprecedented highs and life on Earth presently faces a sixth mass extinction event driven by anthropogenic activity, climate change and ecological collapse. The field of conservation genetics aims at preserving species by using their levels of genetic diversity, usually measured as neutral ...
arxiv +1 more source
Genetics, 2018 In the article by S. Casillas and A. Barbadilla (GENETICS 205: 1003–1035) entitled “Molecular Population Genetics,” on page 1010, the references provided in Table 1 were incomplete. For the measure/test vA, the reference to “Castellano et al.
Matthew W. Hahn
semanticscholar +1 more source
Population-Matched Transcriptome Prediction Increases TWAS Discovery and Replication Rate
iScience, 2020 Summary: Most genome-wide association studies (GWAS) and transcriptome-wide association studies (TWAS) focus on European populations; however, these results cannot always be accurately applied to non-European populations due to genetic architecture ...
Elyse Geoffroy +2 more
doaj
Population genetics and GWAS: A primer. [PDF]
PLoS Biology, 2018 This primer provides some background to help non-specialists understand a new theoretical evolutionary genetics study that helps explain why thousands of variants of small effect contribute to complex traits.
Greg Gibson
doaj +1 more source
Population genetics models of local ancestry
, 2012 Migrations have played an important role in shaping the genetic diversity of human populations. Understanding genomic data thus requires careful modeling of historical gene flow.
Falush, Li, Simon Gravel
core +1 more source
Scientific ReportsInbreeding depression, the loss of offspring fitness due to consanguineous mating, is generally detrimental for individual performance and population viability.
A. J. Paijmans +6 more
doaj +1 more source