Results 61 to 70 of about 6,731,461 (379)
Population genetics and GWAS: A primer. [PDF]
This primer provides some background to help non-specialists understand a new theoretical evolutionary genetics study that helps explain why thousands of variants of small effect contribute to complex traits.
Greg Gibson
doaj +1 more source
UNLABELLED DnaSP is a Windows integrated software package for the analysis of the DNA polymorphism from nucleotide sequence data. DnaSP version 3 incorporates several methods for estimating the amount and pattern of DNA polymorphism and divergence, and ...
J. Rozas, R. Rozas
semanticscholar +1 more source
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali+3 more
wiley +1 more source
The evolutionary history of LysM-RLKs (LYKs/LYRs) in wild tomatoes
Background The LysM receptor-like kinases (LysM-RLKs) are important to both plant defense and symbiosis. Previous studies described three clades of LysM-RLKs: LysM-I/LYKs (10+ exons per gene and containing conserved kinase residues), LysM-II/LYRs (1–5 ...
Sarah Richards, Laura E. Rose
doaj +1 more source
gPGA: GPU Accelerated Population Genetics Analyses. [PDF]
The isolation with migration (IM) model is important for studies in population genetics and phylogeography. IM program applies the IM model to genetic data drawn from a pair of closely related populations or species based on Markov chain Monte Carlo ...
Chunbao Zhou+3 more
doaj +1 more source
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac+3 more
wiley +1 more source
Exploring the effects of ecological parameters on the spatial structure of genetic tree sequences
Geographic space is a fundamental dimension of evolutionary change, determining how individuals disperse and interact with each other. Consequently, space has an important influence on the structure of genealogies and the distribution of genetic variants
Ianni-Ravn, Mariadaria K.+2 more
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In silico characterization of coding and non-coding SNPs of the androgen receptor gene
The Androgen Receptor (AR), an important ligand-dependent nuclear transcription factor, encoded by the AR gene, functions in regulating the cell proliferation, migration, invasion, and apoptosis pathways. Single nucleotide polymorphisms (SNPs) of AR have
Maisha Adiba+6 more
doaj
Population genetic characteristics of Hainan medaka with whole-genome resequencing
The DMY gene is deleted in all males of the Sanya population (SY-medaka) of the Hainan medaka, Oryzias curvinotus, as recently reported by us. However, due to limited knowledge regarding their population genetic background, it is difficult to explore the
Zebin Yao+15 more
doaj +1 more source
The population genetics of parasitic nematodes of wild animals
Parasitic nematodes are highly diverse and common, infecting virtually all animal species, and the importance of their roles in natural ecosystems is increasingly becoming apparent.
Rebecca Cole, M. Viney
semanticscholar +1 more source