Results 181 to 190 of about 3,805,832 (247)

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Ground-Level Ozone as Community-Acquired Pneumonia Risk Factor in Different Population Groups in Summer: The Case of Moscow. [PDF]

Toxics
Dudorova N, Belan B, Kotel'nikov S.
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Barriers and Opportunities to Include Underrepresented Population Groups in Vaccine Trials: Cross-Sectional, Observational, Online Survey Study From the VACCELERATE Research Network. [PDF]

JMIR Public Health Surveill
Tanriover MD, Poulimeneas D, Tsopela GC, Kopsidas I, Argyropoulos C, Di Marzo R, Valdenmaiier O, Jakobsen SF, Valle Simon P, Carcas-Sansuan AJ, Olesen OF, Cornely OA, Pana ZD, Zaoutis T, Akova M.   +14 more
europepmc   +1 more source

Author's Response to Letter on "Willingness to Pay for HIV Prevention Commodities Among Key Population Groups in Nigeria". [PDF]

Glob Health Sci Pract, 2023
Durosinmi-Etti O, Nwala EK, Oki F, Ikpeazu A, Godwin E, Umoh P, Shaibu A, Ogundipe A, Kalaiwo A.   +8 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Sorting out assortativity: When can we assess the contributions of different population groups to epidemic transmission? [PDF]

PLoS One
Geismar C, White PJ, Cori A, Jombart T.
europepmc   +2 more sources

Using decision tree analysis to identify population groups at risk of subjective unmet need for assistance with activities of daily living. [PDF]

BMC Geriatr, 2023
Jaehn P, Fügemann H, Gödde K, Holmberg C.   +3 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Trends in Rates of Heat-Related Deaths Across Population Groups in the United States, 2000-2023. [PDF]

Public Health Rep
Hong YR, Dalisay FS, Xie Z.
europepmc   +1 more source