Results 81 to 90 of about 374,493 (293)

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi   +5 more
wiley   +1 more source

Aeos: The Impact of Population III Initial Mass Function and Star-by-star Models in Galaxy Simulations

open access: yesThe Astrophysical Journal
We explore the effect of variations in the Population III initial mass function (IMF) and star-by-star feedback on early galaxy formation and evolution using the A eos simulations. We compare simulations with two different Population III IMFs: M _char  = 
Kaley Brauer   +9 more
doaj   +1 more source

Synthetic properties of bright metal-poor variables. II. BL Her stars

open access: yes, 2007
We investigate the properties of the so-called BL Her stars, i.e., Population II Cepheids with periods shorter than 8 days, using updated pulsation models and evolutionary tracks computed adopting a metal abundance in the range of Z=0.0001 to Z=0.004. We
Bessell   +51 more
core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Discovery of an [Fe/H] ∼ −4.8 Star in Gaia XP Spectra

open access: yesThe Astrophysical Journal Letters
We report on the discovery of GDR3_526285 (Gaia DR3 Source ID 5262850721755411072), a star with [Fe/H] = −4.82 ± 0.25 and one of the lowest metal (atomic number > 2) mass fractions ever found ( Z _GDR3 _ _526585  ≲ 1.0 × 10 ^−6 ).
Guilherme Limberg   +7 more
doaj   +1 more source

HST Observations of Chromospheres in Metal Deficient Field Giants

open access: yes, 2007
HST high resolution spectra of metal-deficient field giants more than double the stars in previous studies, span about 3 magnitudes on the red giant branch, and sample an abundance range [Fe/H]= -1 to -3.
A. K. Dupree   +19 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

SDSS J0018-0939: A Clear Signature of Sub-Chandrasekhar Mass Type 1a Supernova

open access: yesThe Astrophysical Journal
Very metal-poor (VMP) stars ([Fe/H] ≤ −2) that have subsolar values of [X/Fe] for α elements such as Mg, Si, and Ca, are referred to as α -poor VMP stars.
S. K. Jeena, Projjwal Banerjee
doaj   +1 more source

Population III stars and the Long Gamma Ray Burst rate

open access: yes, 2011
Because massive, low-metallicity population III (PopIII) stars may produce very powerful long gamma-ray bursts (LGRBs), high-redshift GRB observations could probe the properties of the first stars.
Abel   +69 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

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