Results 111 to 120 of about 3,671,924 (308)

Traffic Accessibility and the Effect on Firms and Population in 99 Austrian Regions [PDF]

open access: yes
In this paper we describe the EAR (regional economic accessibility) model to investigate the impact of the improvement of railroad infrastructure on regional GDP, population and firms growth in 99 Austrian regions.
Polasek, Wolfgang   +1 more
core  

EVALUASI DAN RENCANA PENGEMBANGAN SISTEM PENYEDIAAN AIR BERSIH PDAM KABUPATEN SRAGEN DAERAH PELAYANAN KECAMATAN SIDOHARJO [PDF]

open access: yes, 1999
Sub Sidoharjo in Sragen, Central Java Province, with the number of villages as many as 12 villages and the planning area as much as six villages. District population growth rate is 0.19% Sidoharjo per year.
Budihardjo, Mochamad Arief   +2 more
core  

Improving Population Censuses Around the World

open access: yes
Population censuses provide a wide range of detailed information, but are expensive and infrequent. Some more frequent information can be obtained using administrative data sources, which can also be combined with some directly collected information. This combination of sources requires new approaches to produce objective census estimates.
Smith, Paul A.   +2 more
openaire   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

2015 Wisconsin Health Trends: Making Wisconsin the Healthiest State [PDF]

open access: yes, 2016
The Wisconsin State Health Plan for 2020 established a goal for all state residents to live longer and better. Progress toward this goal can be measured by monitoring health outcomes -- and the factors that contribute to those outcomes -- for the state's

core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

When Do We Learn to Cooperate? The Role of Social Learning in Social Dilemmas [PDF]

open access: yes
In this paper, I look at the interaction between social learning and cooperative behavior. I model this using a social dilemma game with publicly observed sequential actions and asymmetric information about payoffs.
James A. Best
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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