Results 121 to 130 of about 2,095,765 (308)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Index des noms cités dans les articles [PDF]

, 1972
Index des noms cités dans les articles. In: Population, 27ᵉ année, n°1, 1972. pp.

core  

Vocal Fatigue Index in Finnish-Speaking Population

Journal of Voice
Vocal fatigue is an important complaint that may indicate a voice disorder or a risk thereof. There is a need for a reliable tool to detect and quantify vocal fatigue and distinguish dysphonic and vocally healthy speakers. The Vocal Fatigue Index (VFI) questionnaire has been found valid and reliable among speakers of different languages.
Eliina Kankare, Leena Rantala, Anne-Maria Laukkanen   +2 more
openaire   +4 more sources

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

A new perspective on socioeconomic drought: a distributed and standardized index

Environmental Research Letters
In drought studies, a standardized index has better applicability, and a distributed index can improve our ability to identify the spatial aspects of droughts. However, for socioeconomic drought, none of the existing indices is both spatially distributed
Fangxiu Meng, Suning Liu, Zhiming Han, Yao Wang, Rong Wu, Haiyun Shi   +5 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Changes in the Patch Test Population Over a Ten-Year Period at the Contact Dermatitis Clinic, Siriraj Hospital: A University-Based Tertiary Care Hospital in Thailand

Siriraj Medical Journal, 2017
Background:  There are several factors which have an impact on patch test results. In the past, comparing the populations between different institutes, without appropriate indicators was difficult.
Sutasinee Phaitoonwattanakij, Waranya Boonchai   +1 more
doaj  

Variations in Nasal Index among Punjabi Population: A Cross-sectional Study

Journal of Clinical and Diagnostic Research
Introduction: Anthropometry serves as a scientific framework for collecting and analysing morphometric data, enabling the study of human diversity across geographical and ethnic boundaries. The nasal index is a multifaceted anatomical entity.
Rishu, Anupama Mahajan, Punita Sharma
doaj   +1 more source

A Further Note on the Age Index of a Population [PDF]

Proceedings of the National Academy of Sciences, 1922
R, Pearl, T J, Leblanc
openaire   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source