Results 101 to 110 of about 7,510,284 (318)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Optimizing Finite Population Mean Estimation Using Simulation and Empirical Data

Mathematics
Two-phase sampling is an effective sampling approach that is useful in sample surveys when prior auxiliary information is not available. When two variables have an association, the ranks of the auxiliary variable are proportional to the study variable ...
Abdulaziz S. Alghamdi, Fatimah A. Almulhim   +1 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Estimation of finite population mean using dual auxiliary information under non-response with simple random sampling

Alexandria Engineering Journal
This paper proposes a new family of estimators for population mean with a non-response using a simple random sampling. It specifically applies this method to estimate the mean in Turkey’s Education sector data sets, accounting for non-response. The study
Fatimah A. Almulhim, Hassan M. Aljohani, Ramy Aldallal, Manahil SidAhmed Mustafa, Meshayil M. Alsolmi, Assem Elshenawy, Afaf Alrashidi   +6 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Strong Admissibility of a Set of Confidence Intervals for the Mean of a Finite Population [PDF]

, 1975
V. M. Joshi
openalex   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

258Change in population mean BMI accounts for the majority of change in underweight and obesity [PDF]

, 2021
Maria Laura Caminia Iurilli
openalex   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Estimation of Population Mean in Chain Ratio-Type Estimator under Systematic Sampling

Journal of Probability and Statistics, 2015
A chain ratio-type estimator is proposed for the estimation of finite population mean under systematic sampling scheme using two auxiliary variables. The mean square error of the proposed estimator is derived up to the first order of approximation and is
Mursala Khan, Rajesh Singh
doaj   +1 more source