Results 141 to 150 of about 3,181,850 (358)

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Selection of Genome-Wide SNPs for Pooled Allelotyping Assays Useful for Population Monitoring. [PDF]

open access: yesGenome Biol Evol, 2022
Babineau M   +7 more
europepmc   +1 more source

Delivering effective NHS services to our multiethnic population: collection and application of ethnic monitoring within primary care [PDF]

open access: yes, 2009
Government health policy has emphasised the importance of understanding and tackling ethnic disparities in health and healthcare for at least four decades. Yorkshire & the Humber includes areas with large, well-established minority ethnic populations.
Allmark, Peter, Salway, Sarah
core  

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

Sustained reduction in numbers of Australian fur seal pups: Implications for future population monitoring. [PDF]

open access: yesPLoS One, 2022
McIntosh RR   +8 more
europepmc   +1 more source

Population monitoring for kangaroo management.

open access: yesAustralian Mammalogy, 2004
In wildlife management, the program of monitoring will depend on the management objective. If the objective is damage mitigation, then ideally it is damage that should be monitored. Alternatively, population size (N) can be used as a surrogate for damage, but the relationship between N and damage obviously needs to be known. If the management objective
openaire   +3 more sources

Monitoring the Dutch Phytophtora infestans population for virulence against new R-genes [PDF]

open access: yes
New possibilities offered by marker assisted breeding and GMO breeding have sparked renewed international efforts to breed for durable potato late blight resistance.
Bekkum, P.J., van   +4 more
core   +1 more source

An integrated approach for predicting the fate of reintroduced populations : a thesis presented in partial fulfilment of the requirements for the degree of Masters of Science in Conservation Biology at Massey University, Palmerston North, New Zealand [PDF]

open access: yes, 2017
I provide a comprehensive account of the fate of a reintroduced population of North Island robins (Petroica longipes) at Tawharanui Regional Park, a predator-free peninsular site in the Auckland Region.
Drummond, Faline
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

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