Results 121 to 130 of about 12,172,512 (307)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Assessing the efficacy and cost‐effectiveness of integrating autonomous recording units and point‐count surveys for population monitoring of northern bobwhite (Colinus virginianus)

Ecological Solutions and Evidence
Autonomous recording units (ARUs) have emerged as a useful tool for monitoring a wide range of acoustically signalling wildlife species in a cost‐effective manner, but estimating abundance from acoustic data can be challenging.
William B. Lewis, Clint Johnson, James A. Martin   +2 more
doaj   +1 more source

Insights from 20 years of mammal population research in Indonesia

Oryx
Mammal populations are declining in biodiverse tropical regions. Global analyses have identified Indonesia as a hotspot of vertebrate decline, although relatively few data are available to substantiate these claims.
Ardiantiono, Irene M.R. Pinondang, Desy S. Chandradewi, Gono Semiadi, Freddy Pattiselanno, Jatna Supriatna, Johny S. Tasirin, Nurul L. Winarni, Maria Voigt, Joseph W. Bull, Tatyana Humle, Nicolas J. Deere, Matthew J. Struebig   +12 more
doaj   +1 more source

Camera-based automated monitoring of flying insects in the wild (Camfi). II. flight behaviour and long-term population monitoring of migratory Bogong moths in Alpine Australia. [PDF]

Front Insect Sci, 2023
Wallace JRA, Dreyer D, Reber TMJ, Khaldy L, Mathews-Hunter B, Green K, Zeil J, Warrant E.   +7 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Population monitoring of a Critically Endangered antelope, the mountain bongo, using camera traps and a novel identification scheme

Oryx
Conservation monitoring is paramount for the gathering of information on species and populations in need of conservation actions. However, monitoring of the mountain bongo Tragelaphus eurycerus isaaci, a Critically Endangered antelope endemic to Kenya ...
Tommy Sandri, Mike Prettejohn, Fred Omengo, Bradley Cain, Martin Jones, W. Edwin Harris   +5 more
doaj   +1 more source

Selection of Genome-Wide SNPs for Pooled Allelotyping Assays Useful for Population Monitoring. [PDF]

Genome Biol Evol, 2022
Babineau M, Collis E, Ruffell A, Bunch R, McNally J, Lyons RE, Kotze AC, Hunt PW.   +7 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Current Status of Pulsatilla patens in Latvia—Population Size, Demographic and Seed Viability Indicators, Soil Parameters and Their Relationships

Plants
Pulsatilla patens (L.) Mill. (Eastern pasque flower) is classified as a highly endangered and declining species in Europe. The present research assessed the current status of P. patens in Latvia by collecting data on its distribution in historical places,
Dace Kļaviņa, Anita Osvalde, Guntis Tabors, Gunta Jakobsone   +3 more
doaj   +1 more source

Sustained reduction in numbers of Australian fur seal pups: Implications for future population monitoring. [PDF]

PLoS One, 2022
McIntosh RR, Sorrell KJ, Thalmann S, Mitchell A, Gray R, Schinagl H, Arnould JPY, Dann P, Kirkwood R.   +8 more
europepmc   +1 more source