Results 111 to 120 of about 12,172,512 (307)

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Optimizing Sampling Technique Parameters for Increased Precision and Practicality in Annual Bluegrass Weevil Population Monitoring. [PDF]

Insects, 2023
de Sousa ALV, Kostromytska OS, Wu S, Koppenhöfer AM.   +3 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Feasibility study on using a detection dog to localize hibernacula of Vipera berus

Scientific Reports
The European adder (Vipera berus), classified as critically endangered in Germany, faces severe threats from habitat loss, particularly the decline of primary habitats such as peatlands.
Madita Schemel, Sascha Buchholz, Jelena Mausbach   +2 more
doaj   +1 more source

Sequential sampling plan for fruit fly species of the Genus Anastrepha (Diptera: Tephritidae) in guava orchards

Anais da Academia Brasileira de Ciências
This study aimed to elaborate a sequential sampling plan for Anastrepha species in commercial orchards of guava Psidium guajava Novo Milênio cultivar. Samplings were carried out in three orchards in the State of Mato Grosso do Sul.
JOSÉ NICÁCIO, ISAIAS DE OLIVEIRA, MANOEL A. UCHOA, ODIVAL FACCENDA, ALFREDO R. ABOT, MARCOS G. FERNANDES, FLÁVIO R.M. GARCIA   +6 more
doaj   +1 more source

Multi-surveyor capture-mark-recapture as a powerful tool for butterfly population monitoring in the pre-imaginal stage. [PDF]

Ecol Evol, 2022
Hinneberg H, Döring J, Hermann G, Markl G, Theobald J, Aust I, Bamann T, Bertscheit R, Budach D, Niedermayer J, Rissi A, Gottschalk TK.   +11 more
europepmc   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

A LEAP Forward in Wildlife Conservation: A Standardized Framework to Determine Mortality Causes in Large GPS‐Tagged Birds

Ecology and Evolution
Anthropogenic activities threaten many wildlife populations by increasing mortality rates, making it crucial to identify the locations and causes of mortality to inform conservation actions.
Connor T. Panter, Carina Nebel, Maximilian Raab, Verena Strauss, Clara Freytag, Manuel Wojta, Hannah Böing, Patrick Hacker, Rainhard Raab, Jendrik Windt, Annika Posautz, Anna Kuebber‐Heiss, Patrick Scherler, Martin U. Grüebler, Urs G. Kormann, Martin Kolbe, Alexandre Millon, Javier de laPuente, Javier Viñuela, Duncan Orr‐Ewing, Oliver Krone, Torsten Langgemach, Susanne Åkesson, Brady Mattsson, Petra Sumasgutner, Manuel Alcántara de la Fuente, Ernesto Alvarez, Juan Arizaga, Albert Bach Pagès, Ana Bermejo, Guido Ceccolini, Nayden Chakarov, Peter Derpmann‐Hagenström, Marek Dostál, Gerd Fabian, Wolfgang Fiedler, Manuel Galán, Clément Ganier, Andreas Gärtner, Liza Glesener, Alfonso Godino, Zuzana Guziová, László Haraszthy, Caka Karlsson, Katharina Klein, Ivan Literák, Nicolas Lorenzini, Manuela Löwold, Christopher Lüning, Boris Maderič, Karel Makoň, Kerstin Mammen, Ubbo Mammen, Torsten Marczak, Hynek Matušík, Aymeric Mionnet, Sara Morollón, Jakub Mráz, Winfried Nachtigall, Bernd Nicolai, Marta Olalde Fernández, Meinolf Ottensmann, María Jesús Palacios González, Jean‐Yves Paquet, Vladimír Pečeňák, Lubomír Peške, Thomas Pfeiffer, Robert Pudwill, Dušan Rak, Tim Maximilian Rapp, Alexander Resetaritz, Stef vanRijn, Romain Riols, Arturo Rodríguez, Luisa Scholze, Laura Schulte, Aurélie deSeynes, Jan Škrábal, Péter Spakovszky, Eike Steinborn, Ján Svetlík, Samuel Talhoet, Miklós Vaczi, Anne‐Gaelle Verdier, Zdenĕk Vermouzek, Diego Villanúa Inglada, Jörg Westphal, Rainer Raab   +87 more
doaj   +1 more source

Threatened or poorly known? The case of the Mediterranean narrow endemic Valeriana amazonum in Sardinia

Oryx
The Mediterranean flora is characterized by a high number of narrow endemic plant species that are often restricted to a few small populations. One of these species, Valeriana amazonum, a perennial plant occurring only in the Supramontes region of ...
Giuseppe Fenu, Giulia Calderisi, Donatella Cogoni   +2 more
doaj   +1 more source

Time Motion Studies for Conduct of Population Monitoring During Functional Radiological Exercises at Community Reception Centers. [PDF]

Disaster Med Public Health Prep, 2022
Finklea L, Salame-Alfie A, Ansari A.
europepmc   +1 more source