Results 91 to 100 of about 12,172,512 (307)

A methodology for long‐term population monitoring of the endangered key largo cotton mouse

Wildlife Society Bulletin, 2013
The Key Largo cotton mouse (Peromyscus gossypinus allapaticola) was federally listed as Endangered in 1984 due to habitat loss and subsequent population decline, but because of infrequent monitoring, the extent of decline and long‐term population trends ...
Daniel U. Greene, Steven B. Castleberry, Michael T. Mengak   +2 more
doaj   +1 more source

Multidisciplinary population monitoring when demographic data are sparse: a case study of remote trout populations

Ecology and Evolution, 2013
The potential of genetic, genomic, and phenotypic metrics for monitoring population trends may be especially high in isolated regions, where traditional demographic monitoring is logistically difficult and only sporadic sampling is possible.
D. Fraser, Anna M. Calvert, L. Bernatchez, Andrew Coon   +3 more
semanticscholar   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Home blood‐pressure monitoring in a hypertensive pregnant population: cost‐minimization study

Ultrasound in Obstetrics and Gynecology, 2019
Traditional blood‐pressure monitoring in hypertensive pregnant women requires frequent visits to the maternity outpatient services. Home blood‐pressure monitoring (HBPM) could offer a cost‐saving alternative that is acceptable to patients.
G. Xydopoulos, H. Perry, H. Perry, E. Sheehan, B. Thilaganathan, B. Thilaganathan, R. Fordham, A. Khalil, A. Khalil   +8 more
semanticscholar   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Mutagénesis ambiental y el uso de biomarcadores para predecir el riesgo de cáncer

Revista de Biología Tropical, 2004
La mutagénesis ambiental o genética toxicológica es una disciplina que tiene como objetivo estudiar el daño genético que conduce a mutaciones, producido por agentes físicos, químicos y biológicos, identificar estos agentes, analizar sus interacciones y ...
Patricia Cuenca, Vanessa Ramírez
doaj  

Thermal Infrared Imaging from Drones Offers a Major Advance for Spider Monkey Surveys

Drones, 2019
Accurate and precise population estimates form the basis of conservation action but are lacking for many arboreal species due to the high costs and difficulty in surveying these species.
Denise Spaan, Claire Burke, Owen McAree, Filippo Aureli, Coral E. Rangel-Rivera, Anja Hutschenreiter, Steve N. Longmore, Paul R. McWhirter, Serge A. Wich   +8 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Silent survivors: how monitoring and genetics reveal the recovery of the Adriatic sturgeon

The European Zoological Journal
The Adriatic sturgeon (Acipenser naccarii) is a critically endangered species that has been the focus of conservation efforts for the past three decades.
C. Samassa, G. Castaldelli, L. Congiu, E. Boscari   +3 more
doaj   +1 more source