Results 91 to 100 of about 8,501,303 (306)
Population Council Strategic Plan 2023–2030 [PDF]
, 2022 For 70 years, the Population Council has transformed global thinking on critical health and development issues through our social science, public health, and biomedical research.
Population Council
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Population trends, convictions and imprisonment: Demographic divergence, dichotomy and diversity [PDF]
, 2006 The links between population patterns and trends, and policy and planning for the justice system is important. The trends in the number of convictions and imprisonments by regional councils are investigated for the period 1986 to 2001. This does not just
Pool, Ian, Baxendine, Sandra
core
Biomedical research at the Population Council [PDF]
, 2015 IN THIS ISSUE: Research and development to improve reproductive health | From bench to bedroom: Biomedical research at the Population Council | Male contraception in discovery | Multipurpose prevention technologies in early-stage development ...
Population Council
core +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
The New Zealand population: A synopsis of trends and projections 1991 - 2016 [PDF]
, 2005 Although there are many excellent documents and online resources available on New Zealand population trends, it is useful to highlight some key trends in one short document. This paper provides a synopsis of trends with respect to population size and age
Hillcoat-Nallétamby, Sarah +4 more
core
On aggregative economic models and population policy [PDF]
, 1971 For more about the East-West Center, see http://www.eastwestcenter.org/The aim of this paper is to set out the requirements of a theory of optimal economic--demographic growth. There are three sections.
McNicoll, Geoffrey +1 more
core +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Population Briefs, Vol. 13, no. 1 [PDF]
, 2007 IN THIS ISSUE: Chemical postmaster helps deliver contraceptive to testis | Complex role for marriage in HIV risk, studies find | Examining the rollout of pediatric antiretroviral treatment in South Africa | Focused antenatal care acceptable, tricky to ...
Population Council
core +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source