Results 81 to 90 of about 8,501,303 (306)

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

U.S. Census Monitoring Board: Congressional Members

, 1998
info:ark/67531/metadc797Congress established the Census Monitoring Board to observe and monitor all aspects of the preparation and implementation of the 2000 decennial census.
U.S. Census Monitoring Board
core  

Video: Population Council 70th Anniversary

, 2022
For 70 years, the Population Council has transformed global thinking on critical health and development issues through our social science, public health, and biomedical research.
Population Council
core   +1 more source

Analysis of sea lamprey environmental DNA during lampricide treatment in a tributary of Lake Ontario

Knowledge and Management of Aquatic Ecosystems, 2020
Sea lamprey (Petromyzon marinus) is a species of invasive parasitic fish in the Great Lakes region of North America. Accurate estimates of larval lamprey populations in lake tributaries are necessary for making control decisions regarding treatment of ...
Tkachuk Kaitlyn A., Dunn David A.
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Development of technology for relocating kulans to preserve their population and restore the biodiversity of their habitat [PDF]

Brazilian Journal of Biology
The reintroduction of the kulan (Equus hemionus kulan) to the Ile-Balkhash State Nature Reserve aims to restore its population within its historical range in Kazakhstan.
A. E. Abdibek, K. T. Abayeva, D. A. Dosmanbetov, M. K. Baibatshanov, A. М. Khamchukova, S. Narbayev, B. B. Yessimbek, R. S. Akhmetov   +7 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Population Briefs, Vol. 9, no. 2 [PDF]

, 2003
IN THIS ISSUE: Education improves breastfeeding practices in Zambia | Focus on newborn survival needed in rural Pakistan | Hormone choice may reduce risks of menopause therapy | Innovative strategies reduce fertility in Ghana | The future of training ...
Population Council
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Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source