Results 81 to 90 of about 3,181,850 (358)
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
A methodology for long‐term population monitoring of the endangered key largo cotton mouse
Wildlife Society Bulletin, 2013 The Key Largo cotton mouse (Peromyscus gossypinus allapaticola) was federally listed as Endangered in 1984 due to habitat loss and subsequent population decline, but because of infrequent monitoring, the extent of decline and long‐term population trends ...
Daniel U. Greene +2 more
doaj +1 more source
On the Properties of the Reaction Counts Chemical Master Equation [PDF]
, 2019 The reaction counts chemical master equation (CME) is a high-dimensional variant of the classical population counts CME. In the reaction counts CME setting, we count the reactions which have fired over time rather than monitoring the population state ...
Sunkara, Vikram
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Thermal Infrared Imaging from Drones Offers a Major Advance for Spider Monkey Surveys
Drones, 2019 Accurate and precise population estimates form the basis of conservation action but are lacking for many arboreal species due to the high costs and difficulty in surveying these species.
Denise Spaan +8 more
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Mutagénesis ambiental y el uso de biomarcadores para predecir el riesgo de cáncer
Revista de Biología Tropical, 2004 La mutagénesis ambiental o genética toxicológica es una disciplina que tiene como objetivo estudiar el daño genético que conduce a mutaciones, producido por agentes físicos, químicos y biológicos, identificar estos agentes, analizar sus interacciones y ...
Patricia Cuenca, Vanessa Ramírez
doaj
Gender wage differentials in Brazil : trends over a turbulent era [PDF]
Since the late 1980s, macroeconomic and trade reform in Brazil appears to have been accompanied by a substantial improvement in the position of women compared with men in the labor market, despite only modest changes to labor market institutions.
Andrew Henley +2 more
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