Results 91 to 100 of about 11,596,072 (260)
Demographic change and transport needs in the Waikato region [PDF]
, 2005 This report has been commissioned by Environment Waikato (EW) as part of its review of the Land Transport Strategy for the Waikato region. The report identifies key population characteristics that impact on transport needs of the EW region and the ...
Baxendine, Sandra +2 more
core
Biomedical research at the Population Council [PDF]
, 2015 IN THIS ISSUE: Research and development to improve reproductive health | From bench to bedroom: Biomedical research at the Population Council | Male contraception in discovery | Multipurpose prevention technologies in early-stage development ...
Population Council
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Drugs, Market Size and Population [PDF]
This paper addresses the upward trend in new drugs introduced by pharmaceutical firms, during the second half of the 20th century. We indicate that the continuous increases in population, and thus in the market size of this sector, will play a ...
Rodrigo Cerda
core
Population Briefs, Vol. 13, no. 1 [PDF]
, 2007 IN THIS ISSUE: Chemical postmaster helps deliver contraceptive to testis | Complex role for marriage in HIV risk, studies find | Examining the rollout of pediatric antiretroviral treatment in South Africa | Focused antenatal care acceptable, tricky to ...
Population Council
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
BirdsThe Turtle Dove is a regular migratory species widely distributed in Italy, though the information on its abundance in each Italian region is modest; thus, action plans have been implemented to improve its conservation.
Simona Tarricone +9 more
doaj +1 more source
Hystrix, the Italian Journal of Mammalogy, 1993 <strong>Abstract</strong> The present research on alpine Brown bears (<em>Ursus arctos</em> L.), covers a period of five years (1987-1991) of collection of data about the status of this population in Western Trentino ...
Fabio Osti
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source