Results 111 to 120 of about 7,806,372 (301)
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
, 2011 Hepatitis C virus (HCV) coinfection has become one of the most challenging clinical situations to manage in HIV-infected patients. Recently the effect of HCV coinfection on HIV dynamics following initiation of highly active antiretroviral therapy (HAART)
Hogan, Joseph W., Su, Li
core +1 more source
Odious Debts or Odious Regimes [PDF]
, 2007 Odious regimes have always been there. That there is no silver-bullet solution that will prevent odious regimes from arising, or stymie them once they do, is evident from the plethora of responses employed by the international community once a regime ...
Bolton, Patrick, Skeel, David
core +5 more sources
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Evolutionary biology and genetic techniques for insect control [PDF]
, 2015 The requirement to develop new techniques for insect control that minimize negative environmental impacts has never been more pressing. Here we discuss population suppression and population replacement technologies. These include sterile insect technique,
Bolton, Michael +2 more
core +1 more source
BMJ Global Health, 2017 Protecting individuals and households against mosquito bites with long-lasting insecticidal nets (LLINs) or indoor residual spraying (IRS) can suppress entire populations of unusually efficient malaria vector species that predominantly feed indoors on ...
G. Killeen +12 more
semanticscholar +1 more source
Radiation damage and immune suppression in splenic mononuclear cell populations [PDF]
Clinical and Experimental Immunology, 1997 SUMMARY We have examined alterations in all of the major splenic mononuclear cell (SMNC) populations in C57Bl/6 mice following whole-body irradiation (0–700 cGy) in order to determine which populations may play a role in active immune suppression and/or haematopoietic recovery.
N P, Harrington +3 more
openaire +2 more sources
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Superconductivity-induced optical anomaly in an iron arsenide [PDF]
, 2010 One of the central tenets of conventional theories of superconductivity, including most models proposed for the recently discovered iron-pnictide superconductors, is the notion that only electronic excitations with energies comparable to the ...
Boris, A. V. +7 more
core +3 more sources
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source