Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Reply to MacColl: Repeated evolution from standing genetic variation. [PDF]
Roesti M +4 more
europepmc +1 more source
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo +7 more
wiley +1 more source
Comprehensive Analysis of 122 Guinea Fowl Genomes Across Three Continents Delineates Their Domestication and Evolutionary Patterns with Special Reference to India. [PDF]
Tomar S +7 more
europepmc +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Mitogenomic Insight into the Population Genetic Diversity and Phylogeography of Soybean Stink Bug (<i>Riptortus pedestris</i>) in China. [PDF]
Zhou Y +10 more
europepmc +1 more source
Genetic Susceptibility to Rheumatic Heart Disease: A Narrative Literature Review Highlighting Evidence From African Populations and Research Gaps in Sudan. [PDF]
Alkhalifamohamed H +3 more
europepmc +1 more source
Latitudinal Clines in Gene Flow and Demographic Stability Reveal Drivers of Microendemism in a Radiation of Alpine Grasshoppers. [PDF]
Ortego J +3 more
europepmc +1 more source
Genetic Structure and Historical Dynamics of the Economic Species <i>Phascolosoma esculenta</i> in Southeastern China. [PDF]
Ma B, Zhou J, Wu G, Zhu C, Zhu J, Wu X.
europepmc +1 more source

