Results 71 to 80 of about 102,028,495 (188)

Development of a Novel Polyleucine‐Based Immunopotentiator for Subunit Vaccines Against Group A Streptococcus

Small, Volume 22, Issue 22, 17 April 2026.
Self‐assembling amphiphilic peptide L15K6 is used as a novel immunoadjuvant for the development of a Group A Streptococcus vaccine. Robust antigen‐specific IgG responses are generated and manage to kill isolated strains of Group A Streptococcus. Cellular and bulk RNA sequencing data reveals that L15K6 regulates immune responses potentially through TLR ...
Lantian Lu, Jazmina L. Gonzalez Cruz, Rabina Giri, Yuexiao Zhang, Sahra Bashiri, Leslie C. Domínguez Cadena, Shuhang Li, Zeinab G. Khalil, Waleed M. Hussein, Jingwen Wang, Jolynn Kiong, Xuehan Lu, Jiahui Zhang, Miao Lu, Wenbin Huang, Wei Yang Kong, Ummey Jannatun Nahar, Prashamsa Koirala, Zhong Guo, Patricia Walden, Antje Blumenthal, Jakob Begun, Kirill Alexandrov, Istvan Toth, Rachel J. Stephenson, Mariusz Skwarczynski   +25 more
wiley   +1 more source

Characterization of a New Disease Syndrome Associated with Porcine Circovirus Type 2 in Previously Vaccinated Herds

, 2011
Porcine circovirus-associated disease (PCVAD) encompasses a group of wasting syndromes linked to porcine circovirus type 2 (PCV2). This paper describes a new PCV2 disease syndrome, called acute pulmonary edema (APE), which, unlike other PCVAD syndromes ...
Steven Henry, Jianfa Bai, Ada G. Cino-Ozuna, Raymond R. R. Rowland, Jerome C. Nietfeld, H. Morgan Scott, Richard Hesse   +6 more
core   +1 more source

Droplet Digital CRISPR for Nucleic Acid Detection

Advanced Science, Volume 13, Issue 14, 9 March 2026.
This review outlines recent advances in droplet digital CRISPR technology for nucleic acid detection, combining CRISPR specificity with droplet digital‐based absolute quantification. It summarizes core principles, amplification‐assisted and amplification‐free strategies, and representative DNA and RNA biomarker applications.
Yang Zhang, Roy S. K. Walker, Anwar Sunna, Tracie J. Barber, Ming Li   +4 more
wiley   +1 more source

Full-Length Genome Sequences of Two Chinese Porcine Circovirus Type 3 Strains, NWHEB21 and NWHUN2

, 2018
Two porcine circovirus 3 (PCV3) strains, named NWHEB21 and NWHUN2, were identified in heart and brain tissues of aborted piglets. Their complete genome sequences were sequenced and analyzed to further characterize PCV3 in China and worldwide.
Fanwei Meng, Rui Chen, Qinghong Xue, Enqi Du, Shasha Chen, Zhigang Zhang, Can Liu   +6 more
core   +1 more source

A novel kirkovirus may be associated with equine gastrointestinal disease

Equine Veterinary Journal, Volume 58, Issue 2, Page 414-422, March 2026.
Abstract Background Many cases of equine enterocolitis are suspected to be infectious in nature, but no pathogen is identified in many cases. Objectives Perform next‐generation sequencing on faeces collected from cases of equine enterocolitis for the presence of novel viruses and determine if an identified novel virus is associated with cases of equine
Lillian M. B. Haywood, Ava Clark, Ben Hause, Breanna Sheahan   +3 more
wiley   +1 more source

The prevalence and genetic characteristics of porcine circovirus type 2 and 3 in Korea

BMC Veterinary Research, 2018
Background Porcine circovirus-associated diseases (PCVAD), caused by porcine circovirus type 2 (PCV2), threaten the pig industry worldwide. Five genotypes of PCV2 were recently identified: PCV2a, PCV2b, PCV2c, PCV2d and PCV2e.
Seung-Chai Kim, Salik Nazki, Sam Kwon, Jhung-Hyun Juhng, Kyeong-Hwan Mun, Do-Young Jeon, Chang-Gi Jeong, Amina Khatun, Seog-Jin Kang, Won-Il Kim   +9 more
doaj   +1 more source

Complete Genome Sequence of a Novel Porcine Circovirus-Like Agent

, 2012
We report here the genome sequence of a porcine circovirus-like agent. The sequenced genome of this porcine circovirus-like agent is composed of a 648-nucleotide circular DNA that includes three predicted protein-coding genes, which means the agent ...
JunMing Zhou, ZhengYu Yu, LiXin Lv, KongWang He, XueHan Zhang, XiaoMin Wang, LiBin Wen, RongLi Guo, YanXiu Ni, AiHua Mao, Bin Li   +10 more
core   +1 more source

Revisiting Porcine Circovirus Infection: Recent Insights and Its Significance in the Piggery Sector

, 2023
Porcine circovirus (PCV), a member of the Circoviridae family within the genus Circovirus, poses a significant economic risk to the global swine industry. PCV2, which has nine identified genotypes (a–i), has emerged as the predominant genotype worldwide,
Hemanta Maity, Vivek Gupta, Rajib Deb, Kartik Samanta, Vivek Kumar Gupta, Hemanta Kumar Maity   +5 more
core   +1 more source

Pathogenesis and Transmission of a Reassorted H1 Influenza A Virus Detected in North American Swine

Influenza and Other Respiratory Viruses, Volume 20, Issue 2, February 2026.
ABSTRACT Background The USDA influenza A virus in swine national surveillance plan identified an increase in the detection frequency of a group of swine 1A.1.1.3 hemagglutinin (HA) clade viruses. This change was associated with reassortment events that resulted in new neuraminidase (NA) gene pairings.
Débora B. Goulart, Carine K. Souza, Giovana C. Zanella, Celeste A. Snyder, Janice C. Zanella, Alexey Markin, Bailey Arruda, Tavis K. Anderson, Amy L. Baker   +8 more
wiley   +1 more source

Optimized real-time fluorescence PCR assay for the detection of porcine Circovirus type 3 (PCV3)

BMC Veterinary Research, 2020
Background Porcine circovirus type 3 (PCV3) has been an emerging porcine virus spread around the world. The conserved DNA sequence of PCV3 enabled good performance in molecular biological assays.
Lin Yuan, Yingyi Liu, Yana Chen, Xiaoxue Gu, Hao Dong, Shuo Zhang, Tao Han, Zhi Zhou, Xiaohui Song, Chuanbin Wang   +9 more
doaj   +1 more source