Results 61 to 70 of about 102,030,339 (160)

High detection frequency and genetic diversity of porcine circovirus 3 (PCV-3) in Namibian backyard farms and warthogs

open access: yesActa Tropica
Since its first identification in 2015, porcine circovirus 3 (PCV-3) has been reported worldwide with a high frequency and in the presence of several clinical conditions, although its impact on pig health and productivity is still debated. Data on the presence of PCV-3 in Africa are, however, limited.
Molini U.   +9 more
openaire   +4 more sources

The analysis of genome composition and codon bias reveals distinctive patterns between avian and mammalian circoviruses which suggest a potential recombinant origin for Porcine circovirus 3.

open access: yesPLoS ONE, 2018
Members of the genus Circovirus are host-specific viruses, which are totally dependent on cell machinery for their replication. Consequently, certain mimicry of the host genome features is expected to maximize cellular replicative system exploitation and
Giovanni Franzo   +4 more
doaj   +1 more source

Development and Field Validation of a Double‐Antigen Sandwich Colloidal Gold Immunochromatographic Strip for Detection of Toxoplasma gondii Antibodies in Multiple Host Species

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Toxoplasmosis, a globally prevalent zoonosis caused by Toxoplasma gondii (T. gondii), poses major threats to both human and animal health, leading to reproductive losses in livestock and severe disease in immunocompromised individuals. Although enzyme‐linked immunosorbent assay (ELISA) and PCR are widely used for diagnosis and surveillance, they may be
Xin Mu   +8 more
wiley   +1 more source

3D models of proteins and conservative G-quadruplexes in the genome of porcine circovirus

open access: yesБіофізичний вісник
Background: Non-canonical structures formed in nucleic acid molecules, which include, in particular, multihelical connections 3WJs (three-way junctions), quadruplexes (G4s), are regulatory elements that affect the functioning of the genome.
O. Yu. Limanskaya   +3 more
doaj   +1 more source

A Novel In‐Cell ELISA With Superior Sensitivity and Specificity for the Detection of African Swine Fever Virus‐Specific IgM and IgG Antibodies

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
African swine fever (ASF), a high‐profile transboundary animal disease caused by ASF virus (ASFV), imposes a devastating impact on the global swine industry. Given that vaccines are still under development, including field evaluations, early detection of ASFV is crucial for effective disease control and mitigation.
Ping Wu   +5 more
wiley   +1 more source

The porcine circovirus type 1 capsid gene promoter improves antigen expression and immunogenicity in a HIV-1 plasmid vaccine

open access: yesVirology Journal, 2011
Background One of the promising avenues for development of vaccines against Human immunodeficiency virus type 1 (HIV-1) and other human pathogens is the use of plasmid-based DNA vaccines.
Burger Marieta   +5 more
doaj   +1 more source

High levels of maternally derived antibodies do not significantly interfere with the development of humoral and cell-mediated responses to Porcine circovirus 2 after intradermal vaccination

open access: yesPorcine Health Management, 2023
Background Vaccination of pigs against PCV2 is usually performed around weaning when animals still have maternally derived antibodies (MDA). The present study aimed to assess the possible interference of MDA in the development of the PCV2-specific immune
Gerard E. Martin-Valls   +4 more
doaj   +1 more source

Metagenomic analysis of endemic viruses in oral secretions from Chinese pigs

open access: yesVeterinary Medicine and Science, 2022
Background Pigs are unique reservoirs for virus ecology. Despite the increased use of improved biosecurity measures, pig viruses readily circulate in Chinese swine farms.
Sajid Umar   +5 more
doaj   +1 more source

Resolving the Phylogenetic Placement of the FSfaCV/PCV5‐Related Viruses Within the Genus Macochavirus

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Metagenomic analysis of fecal samples from diarrheic pigs in China identified 10 complete circular single‐stranded DNA viral genomes previously designated as putative porcine circovirus 5 (PCV5)–like viruses. Genome characterization revealed a typical cressdnavirus organization with bidirectionally oriented Rep and Cap genes.
Wenqiang Wang   +9 more
wiley   +1 more source

Animal Welfare‐Friendly Noninvasive Oral Fluid in Swine Diagnostics: Current Applications in Disease Monitoring, Key Challenges and Future Directions

open access: yesVeterinary Medicine International, Volume 2026, Issue 1, 2026.
The integration of oral fluid (OF) sampling into veterinary diagnostics represents a significant shift in animal herd health monitoring, offering a noninvasive alternative to traditional blood‐based methods. OF, predominantly composed of saliva, mucosal transudate and plasma‐derived components, contains immunoglobulins, acute‐phase proteins and nucleic
Chandra Shaker Chouhan   +4 more
wiley   +1 more source

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