Results 41 to 50 of about 9,360 (134)
Advanced Science, Volume 13, Issue 54, 28 September 2026.Porcine deltacoronavirus (PDCoV) infection induces severe intestinal inflammation and acute diarrhea in piglets, yet the molecular mechanism remains incompletely understood. The M protein activates NLRP3 inflammasome through dual mechanisms: direct binding to the NLRP3 LRR domain and disruption of TRIM31‐mediated K48‐linked ubiquitination.
Jinhui Hou +11 more
wiley +1 more source
ChemistryOpen, Volume 15, Issue 9, September 2026.Gold nanoparticle‐assisted multiplex PCR enables the simultaneous detection of six major hospital‐acquired infection‐associated pathogens by improving amplification performance and assay specificity, providing an analytical proof‐of‐concept for rapid molecular identification.
Kubra Aslan +2 more
wiley +1 more source
Frontiers in Veterinary Science, 2022 Porcine epidemic diarrhea virus (PEDV) is a serious infectious causative agent in swine, especially in neonatal piglets. PEDV genotype 2 (G2) strains, particularly G2a, were the primary causes of porcine epidemic diarrhea (PED) outbreaks in Vietnam. Here,
Thuong Thi Ho +14 more
doaj +1 more source
Electrochemical Science Advances, Volume 6, Issue 4, August 2026.ABSTRACT Rapid and sensitive detection of disease‐related biomarkers is critical for early diagnosis and appropriate treatment. However, conventional analytical methods are often time‐consuming and require complex procedures and skilled personnel.
Minju Ahn +4 more
wiley +1 more source
Advancing Antiviral Design: Integrating Natural Products, Computation and Targeted Delivery
Chemical Biology &Drug Design, Volume 108, Issue 1, July 2026.A stepwise translational framework linking natural‐product discovery, computational prioritisation, experimental validation, lead optimisation and targeted delivery is proposed to advance antiviral design. ABSTRACT The COVID‐19 pandemic highlighted the role of rapid viral mutation and global connectivity in accelerating viral emergence and spread ...
Adedayo Ayodeji Lanrewaju +3 more
wiley +1 more source
BMC Veterinary Research, 2019 Background In China, large-scale outbreaks of severe diarrhea caused by viruses have occurred in pigs since late 2010. To investigate the prevalence and genetic evolution of diarrhea-associated viruses responsible for the outbreaks, a total of 2987 field
Fanfan Zhang +10 more
doaj +1 more source
Organoids: From Bench to Bedside Applications
MedComm, Volume 7, Issue 6, June 2026.Organoids, as a groundbreaking biomedical research platform, utilize adult stem cells (ASCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs) as sources. By integrating specific growth and differentiation signals within an extracellular matrix (e.g., Matrigel), organoids guide cells to self‐assemble into three‐dimensional ...
Kelin Li +6 more
wiley +1 more source
Pathology of US Porcine Epidemic Diarrhea Virus Strain PC21A in Gnotobiotic Pigs
Emerging Infectious Diseases, 2014 To understand the progression of porcine epidemic diarrhea virus infection, we inoculated gnotobiotic pigs with a newly emerged US strain, PC21A, of the virus.
Kwonil Jung +5 more
doaj +1 more source
Microbial Biotechnology, Volume 19, Issue 6, June 2026.By displaying the hemagglutinin (HA) or neuraminidase (NA) proteins of influenza viruses on the surface of baculoviruses and infected insect cells, a safe and flexible pseudovirus system capable of performing cytokine analysis, serological detection and antiviral drug screening is established.
Li‐Yun Cheng +7 more
wiley +1 more source
New Variants of Porcine Epidemic Diarrhea Virus, China, 2011
Emerging Infectious Diseases, 2012 In 2011, porcine epidemic diarrhea virus (PEDV) infection rates rose substantially in vaccinated swine herds. To determine the distribution profile of PEDV outbreak strains, we sequenced the full-length spike gene from samples from 9 farms where animals ...
Wentao Li +7 more
doaj +1 more source