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Molecular and Structural Evolution of Porcine Epidemic Diarrhea Virus
To analyze the evolutionary characteristics of the highly contagious porcine epidemic diarrhea virus (PEDV) at the molecular and structural levels, we analyzed the complete genomes of 647 strains retrieved from the GenBank database. The results showed that the spike (S) gene exhibited larger dS (synonymous substitutions per synonymous site) values than
Baicheng Huang +4 more
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An inactivated vaccine made from a U.S. field isolate of porcine epidemic disease virus is immunogenic in pigs as demonstrated by a dose-titration [PDF]
Citation: Collin, E. A., Anbalagan, S., Okda, F., Batman, R., Nelson, E., & Hause, B. M. (2015). An inactivated vaccine made from a U.S. field isolate of porcine epidemic disease virus is immunogenic in pigs as demonstrated by a dose-titration.
Anbalagan, S. +5 more
core +3 more sources
Emergence of porcine epidemic diarrhea virus in southern Germany [PDF]
Over the last years, porcine epidemic diarrhea virus (PEDV) has caused devastating enteric diseases in the US and several countries in Asia, while outbreaks in Europe have only been reported sporadically since the 1980s. At present, only insufficient information is available on currently circulating PEDV strains in Europe and their impact on the ...
Stadler, Julia +9 more
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Molnupiravir Inhibits Porcine Epidemic Diarrhea Virus Infection In Vitro
Porcine epidemic diarrhea virus (PEDV) is a swine coronavirus that is highly infectious and prone to variation. Vaccines derived from traditional PEDV strains provide less protection against PEDV-variant strains. Furthermore; there is a complex diversity of sequences among various PEDV-variant strains.
Zi-Xin Huang +3 more
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We carried out pathogen detection of 282 clinical samples collected from Zhejiang Province and its 24 surrounding areas during April 2013 to April 2017. Among them, 16 positive samples were selected for S gene cloning and sequencing.
SHAN Ying +8 more
doaj +1 more source
Porcine epidemic diarrhea (PED) first appeared in England and Belgium in the 1970s. The etiological agent of the disease is porcine epidemic diarrhea virus (PEDV), which belongs to Coronaviridae. The disease has spread globally and became an endemic disease in many Asian and European countries causing transient diarrhea in postweaning pigs with low ...
Peng, Ju-Yi +3 more
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Molecular epidemiology of porcine epidemic diarrhea virus in China [PDF]
Since early 2006, porcine epidemic diarrhea virus (PEDV) has been reemerging in immunized swine herds. Open reading frame 3 (ORF3) is the only accessory gene in the PEDV genome. The entire ORF3 genes of 12 PEDV field strains and one vaccine strain were sequenced. The ORF3 genes of Chinese PEDV field strains (excluding CH/GSJIII/07) contain a single 672-
Chen, Jianfei +7 more
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Newly Characterized Porcine Epidemic Diarrhea Virus GII Subtype Strain
Diarrhea outbreaks in piglets on pig farms are commonly attributed to porcine epidemic diarrhea virus (PEDV) infection. This research analyzed the S gene prevalence variation and recombination patterns in PEDV GII strains. Throughout the previous two years, 172 clinical samples of piglet diarrhea have been collected, from which 24 PEDV isolates have ...
Jiarong Yu +16 more
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Extracellular signal-regulated kinase (ERK) activation is required for porcine epidemic diarrhea virus replication [PDF]
Porcine epidemic diarrhea virus (PEDV) is a highly enteropathogenic coronavirus of swine that causes acute enteritis with high mortality in nursery piglets. To date, the cellular factors involved in PEDV replication have not been well defined.
Kim, Youngnam, Lee, Changhee
core +1 more source
Isolation, identification, and pathogenicity of porcine epidemic diarrhea virus
Porcine epidemic diarrhea (PED) is an enterophilic infectious disease caused by the porcine epidemic diarrhea virus (PEDV), which can lead to dehydration-like diarrhea in piglets with a mortality rate of up to 100%, causing huge economic losses to the global pig industry.
Yingshuo Sun +26 more
openaire +3 more sources

