Results 1 to 10 of about 7,695 (129)

Genetic Diversity, Recombination, and Pathogenicity of Porcine Epidemic Diarrhea Virus Strains Circulating in China During 2023-2024. [PDF]

Transbound Emerg Dis
Porcine epidemic diarrhea virus (PEDV) is an enteric alphacoronavirus that causes severe diarrhea and high mortality in neonatal piglets, posing a persistent threat to the global swine industry. Despite extensive vaccination, PEDV continues to circulate in China, underscoring the need for updated molecular epidemiological surveillance.
Cao Y, Cui A, Chen X, Cheng Y, Tang R, Zeng H, Li Y, Yang Q.   +7 more
europepmc   +2 more sources

Discovery of Cetaben as a Novel Antiviral Agent Against Porcine Epidemic Diarrhea Virus From a Cholesterol-Lowering Compound Library. [PDF]

Transbound Emerg Dis
The devastating impact of porcine epidemic diarrhea virus (PEDV) on the global swine industry underscores an urgent need for effective antiviral therapies. Drug repurposing presents a promising strategy to accelerate the development of such treatments.
Li Y, Qin P, Zhang K, Ma N, Wang T, Chen Z, Yuan Y, Li D, Yu L, Li W, Du W, Li Y.   +11 more
europepmc   +2 more sources

Concomitant Infection With Porcine circovirus 2 and Porcine Epidemic Diarrhea Virus Does Not Increase Enteritis Severity in Experimentally Infected Weaned Piglets. [PDF]

Transbound Emerg Dis
Background Young pigs are often coinfected with porcine circovirus 2 (PCV2) and porcine epidemic diarrhea virus (PEDV). This study aimed to determine the impact of coinfection of pigs with PCV2 and PEDV. Forty 16‐day‐old crossbred mixed‐sex piglets were assigned to four groups (n = 10/group, NEG‐CONTROL, PCV2‐CONTROL, PCV2+PEDV, and PEDV‐CONTROL).
Gerber PF, Zhang J, Noel A, Wang B, Huang Y, Halbur PG, Opriessnig T.   +6 more
europepmc   +2 more sources

Transplacental Transmission of Porcine Epidemic Diarrhea Virus

Frontiers in Veterinary Science, 2022
Because the porcine epidemic diarrhea virus (PEDV) is a critical pathogen resulting in rapid spreading and high mortality rates in piglets, understanding of the transmission route of PEDV is required for its controlling. Until now, it is well known that PEDV transmission routes are various, such as fecal–oral route, contaminated feed, farmworkers, and ...
Jihoon Ryu, Gi-Jong Kang, Onnuri Kim, Jae-Yeon Park, Hyun-Jin Shin, Hyun-Jin Shin   +5 more
openaire   +3 more sources

Molecular and Structural Evolution of Porcine Epidemic Diarrhea Virus

Animals, 2022
To analyze the evolutionary characteristics of the highly contagious porcine epidemic diarrhea virus (PEDV) at the molecular and structural levels, we analyzed the complete genomes of 647 strains retrieved from the GenBank database. The results showed that the spike (S) gene exhibited larger dS (synonymous substitutions per synonymous site) values than
Baicheng Huang, Guoqian Gu, Yunjing Zhang, Zhenzhen Chen, Kegong Tian   +4 more
openaire   +3 more sources

Isolation, identification, and pathogenicity of porcine epidemic diarrhea virus

Frontiers in Microbiology, 2023
Porcine epidemic diarrhea (PED) is an enterophilic infectious disease caused by the porcine epidemic diarrhea virus (PEDV), which can lead to dehydration-like diarrhea in piglets with a mortality rate of up to 100%, causing huge economic losses to the global pig industry.
Yingshuo Sun, Yingshuo Sun, Ting Gong, Ting Gong, Dongdong Wu, Dongdong Wu, Yongzhi Feng, Yongzhi Feng, Qi Gao, Qi Gao, Jiabao Xing, Jiabao Xing, Xiaoyu Zheng, Xiaoyu Zheng, Zebu Song, Zebu Song, Xing Liu, Xiongnan Chen, Xiongnan Chen, Yankuo Sun, Yankuo Sun, Guihong Zhang, Guihong Zhang, Guihong Zhang, Lang Gong, Lang Gong, Lang Gong   +26 more
openaire   +3 more sources

Emergence of porcine epidemic diarrhea virus in southern Germany [PDF]

BMC Veterinary Research, 2015
Over the last years, porcine epidemic diarrhea virus (PEDV) has caused devastating enteric diseases in the US and several countries in Asia, while outbreaks in Europe have only been reported sporadically since the 1980s. At present, only insufficient information is available on currently circulating PEDV strains in Europe and their impact on the ...
Stadler, Julia, Zoels, Susanne, Fux, Robert, Hanke, Dennis, Pohlmann, Anne, Blome, Sandra, Weissenböck, Herbert, Weissenbacher-Lang, Christiane, Ritzmann, Mathias, Ladinig, Andrea   +9 more
openaire   +3 more sources

Identification of the membrane protein of porcine epidemic diarrhea virus [PDF]

Virus Genes, 1995
Sequence information on the genome of porcine epidemic diarrhea virus(PEDV) has only recently been determined. In contrast, very little is known about the viral proteins. In the present report we have identified the membrane glycoprotein (M) of PEDV by use of rabbit anti-peptide sera and transient expression of the cloned M gene in Vero cells and by ...
Utiger A, Tobler K, Bridgen A, Ackermann M   +3 more
openaire   +3 more sources

Propagation of the virus of porcine epidemic diarrhea in cell culture [PDF]

Journal of Clinical Microbiology, 1988
Porcine epidemic diarrhea virus (PEDV) was adapted to serial propagation in Vero cell cultures by adding trypsin to the medium. PEDV-infected cells showed a distinct cytoplasmic fluorescence when examined by a fluorescent-antibody-staining technique. Cytopathic effects, such as vacuolation, formation of syncytia, and fusion of cells, were detected even
Hofmann, M, Wyler, R
openaire   +3 more sources

Molecular epidemiology of porcine epidemic diarrhea virus in China [PDF]

Archives of Virology, 2010
Since early 2006, porcine epidemic diarrhea virus (PEDV) has been reemerging in immunized swine herds. Open reading frame 3 (ORF3) is the only accessory gene in the PEDV genome. The entire ORF3 genes of 12 PEDV field strains and one vaccine strain were sequenced. The ORF3 genes of Chinese PEDV field strains (excluding CH/GSJIII/07) contain a single 672-
Chen, Jianfei, Wang, Chengbao, Shi, Hongyan, Qiu, Huaji, Liu, Shengwang, Chen, Xiaojin, Zhang, Zhibang, Feng, Li   +7 more
openaire   +2 more sources