Results 21 to 30 of about 7,695 (129)

Effects of disinfection on the molecular detection of porcine epidemic diarrhea virus

open access: yesVeterinary Microbiology, 2015
Routine detection of porcine epidemic diarrhea virus (PEDV) is currently limited to RT-PCR but this test cannot distinguish between viable and inactivated virus. We evaluated the capability of disinfectants to both inactivate PEDV and sufficiently damage viral RNA beyond RT-PCR detection.
Bowman, Andrew S.   +6 more
openaire   +2 more sources

Complete Genome Sequence of Porcine Epidemic Diarrhea Virus in Vietnam [PDF]

open access: yesGenome Announcements, 2014
ABSTRACT Porcine epidemic diarrhea virus (PEDV) has emerged in Vietnam since 2009. Herein, full-length genome sequences are reported for three PEDV isolates from pigs displaying severe diarrhea from farms located in northern and southern provinces of Vietnam.
Vui, Dam Thi   +4 more
openaire   +2 more sources

Organoids: From Bench to Bedside Applications

open access: yesMedComm, Volume 7, Issue 6, June 2026.
Organoids, as a groundbreaking biomedical research platform, utilize adult stem cells (ASCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs) as sources. By integrating specific growth and differentiation signals within an extracellular matrix (e.g., Matrigel), organoids guide cells to self‐assemble into three‐dimensional ...
Kelin Li   +6 more
wiley   +1 more source

Applying Baculovirus Surface Display Technology for Influenza Cytokine Profiling, Serological Detection and Antiviral Screening

open access: yesMicrobial Biotechnology, Volume 19, Issue 6, June 2026.
By displaying the hemagglutinin (HA) or neuraminidase (NA) proteins of influenza viruses on the surface of baculoviruses and infected insect cells, a safe and flexible pseudovirus system capable of performing cytokine analysis, serological detection and antiviral drug screening is established.
Li‐Yun Cheng   +7 more
wiley   +1 more source

Molecular Detection of Alpha‐ and Betacoronaviruses in Bats from Afar Region, Ethiopia

open access: yesVeterinary Medicine and Science, Volume 12, Issue 3, May 2026.
Bats are critical reservoirs of coronaviruses, yet gaps remain in understanding coronavirus diversity within bat populations in Eastern Ethiopia. A total of 141 bats were captured: 129 Chaerephon pumilus, 11 Epomophorus labiatus and 1 Mops condylurus. Coronaviruses detected in eight bats.
Bula Mengesha   +2 more
wiley   +1 more source

Complete Genome Sequence of a Porcine Epidemic Diarrhea Virus Variant [PDF]

open access: yesJournal of Virology, 2012
ABSTRACT In 2011, outbreaks of viral diarrhea were observed on most swine-breeding farms in most of the provinces of China. The disease is characterized by vomiting, severe diarrhea, and a high mortality rate (82.3%) in newborn piglets. The clinical appearance was similar to that of porcine epidemic diarrhea virus (PEDV) infection. PEDVs were
Jianfei, Chen   +5 more
openaire   +2 more sources

Coronavirus Nsp3 Hijacks CLTC to Modulate Autophagosome Nucleation for Promoting DMV Formation and Viral Replication

open access: yesAdvanced Science, Volume 13, Issue 24, 27 April 2026.
In wild‐type cells, FIPV infection recruits CLTC to nsp3, facilitates DMV biogenesis and block autophagic flux to promote viral replication. CLTC knockout impairs autophagosome nucleation by reducing Beclin1–ATG14 complex expression. This disrupts the formation of autophagic precursor membranes, thereby preventing their hijacking by nsp3 for DMV ...
Juan Xu   +9 more
wiley   +1 more source

New Variants of Porcine Epidemic Diarrhea Virus, China, 2011

open access: yesEmerging Infectious Diseases, 2012
In 2011, porcine epidemic diarrhea virus (PEDV) infection rates rose substantially in vaccinated swine herds. To determine the distribution profile of PEDV outbreak strains, we sequenced the full-length spike gene from samples from 9 farms where animals exhibited severe diarrhea and mortality rates were high. Three new PEDV variants were identified.
Li, Wentao   +7 more
openaire   +3 more sources

Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents

open access: yesAdvanced Functional Materials, Volume 36, Issue 26, 30 March 2026.
Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras   +6 more
wiley   +1 more source

Molecular characteristics of a novel recombinant of porcine epidemic diarrhea virus [PDF]

open access: yesArchives of Virology, 2019
Porcine epidemic diarrhea (PED) is a contagious viral disease in pigs, caused by the coronavirus porcine epidemic diarrhea virus (PEDV). PEDV infection results in significant mortality in piglets in unvaccinated herds. Like many others RNA viruses, PEDV has high evolutionary rate and is prone to genetic mutations.
Mariia Nefedeva   +2 more
openaire   +3 more sources

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