Results 21 to 30 of about 15,028 (214)

Emergence of a Highly Virulent Porcine Epidemic Diarrhea Virus (PEDV) G2c Subtype in China: Isolation, Genetic and Pathogenic Characterization, and Cross-Neutralizing Antibody Response. [PDF]

open access: yesTransbound Emerg Dis
Porcine epidemic diarrhea virus (PEDV), an enteropathogenic coronavirus causing high mortality in neonatal piglets, continues to threaten global swine industries. Frequent mutations in the spike (S) protein of PEDV, particularly in emerging variants, have substantially compromised commercial vaccine efficacy.
Li YY   +7 more
europepmc   +2 more sources

Nicotinamide Efficiently Suppresses Porcine Epidemic Diarrhea Virus and Porcine Deltacoronavirus Replication

open access: yesViruses, 2023
Porcine epidemic diarrhea virus (PEDV) and porcine deltacoronavirus (PDCoV), members of the genus Coronavirus, mainly cause acute diarrhea, vomiting and dehydration in piglets, and thus lead to serious economic losses. In this study, we investigated the effects of nicotinamide (NAM) on PEDV and PDCoV replication and found that NAM treatment ...
Mingxia Li   +10 more
openaire   +3 more sources

Remdesivir inhibits Porcine epidemic diarrhea virus infection in vitro

open access: yesHeliyon, 2023
Porcine Epidemic Diarrhea Virus (PEDV) is a highly contagious and pathogenic virus that causes symptoms such as diarrhea, vomiting, weight loss, and even death in piglets. Due to its high transmission rate, PEDV has resulted in significant global losses.
Zi-Xin Huang   +4 more
openaire   +3 more sources

Porcine epidemic diarrhea virus: current insights

open access: yesVirus Adaptation and Treatment, 2016
Chaochao Lv,1,* Yan Xiao,1,* Xiangdong Li,1 Kegong Tian,1,2 1National Research Center for Veterinary Medicine, Luoyang, People's Republic of China; 2College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou, People's Republic of China *These authors contributed equally to this review Abstract ...
tian, kegong   +3 more
openaire   +4 more sources

Molecular and Structural Evolution of Porcine Epidemic Diarrhea Virus

open access: yesAnimals, 2022
To analyze the evolutionary characteristics of the highly contagious porcine epidemic diarrhea virus (PEDV) at the molecular and structural levels, we analyzed the complete genomes of 647 strains retrieved from the GenBank database. The results showed that the spike (S) gene exhibited larger dS (synonymous substitutions per synonymous site) values than
Baicheng Huang   +4 more
openaire   +3 more sources

The Advances of Broad-Spectrum and Hot Anti-Coronavirus Drugs

open access: yesMicroorganisms, 2022
Coronaviruses, mainly including severe acute respiratory syndrome virus, severe acute respiratory syndrome coronavirus 2, Middle East respiratory syndrome virus, human coronavirus OC43, chicken infectious bronchitis virus, porcine infectious ...
Sen Zeng   +13 more
doaj   +1 more source

Molnupiravir Inhibits Porcine Epidemic Diarrhea Virus Infection In Vitro

open access: yesViruses, 2023
Porcine epidemic diarrhea virus (PEDV) is a swine coronavirus that is highly infectious and prone to variation. Vaccines derived from traditional PEDV strains provide less protection against PEDV-variant strains. Furthermore; there is a complex diversity of sequences among various PEDV-variant strains.
Zi-Xin Huang   +3 more
openaire   +3 more sources

Emergence of porcine epidemic diarrhea virus in southern Germany [PDF]

open access: yesBMC Veterinary Research, 2015
Over the last years, porcine epidemic diarrhea virus (PEDV) has caused devastating enteric diseases in the US and several countries in Asia, while outbreaks in Europe have only been reported sporadically since the 1980s. At present, only insufficient information is available on currently circulating PEDV strains in Europe and their impact on the ...
Stadler, Julia   +9 more
openaire   +3 more sources

Newly Characterized Porcine Epidemic Diarrhea Virus GII Subtype Strain

open access: yesTransboundary and Emerging Diseases, 2023
Diarrhea outbreaks in piglets on pig farms are commonly attributed to porcine epidemic diarrhea virus (PEDV) infection. This research analyzed the S gene prevalence variation and recombination patterns in PEDV GII strains. Throughout the previous two years, 172 clinical samples of piglet diarrhea have been collected, from which 24 PEDV isolates have ...
Jiarong Yu   +16 more
openaire   +2 more sources

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