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Vero Cells as a Mammalian Cell Substrate for Human Norovirus [PDF]

open access: yesViruses, 2020
Human norovirus (HuNoV) is a principal cause of acute gastroenteritis worldwide, particularly in developing countries. Its global prevalence is underscored by more serious morbidity and some mortality in the young (<5 years) and the elderly. To date, there are no licensed vaccines or approved therapeutics for HuNoV, mostly because there are limited ...
Kyle Todd, Ralph A Tripp, Tripp Ralph A
exaly   +4 more sources

Differences in cytokines expression between Vero cells and IPEC-J2 cells infected with porcine epidemic diarrhea virus

open access: yesFrontiers in Microbiology, 2022
Porcine epidemic diarrhea virus (PEDV) primarily infects suckling piglets and causes severe economic losses to the swine industry. Cytokines, as part of the innate immune response, are important in PEDV infection. The cytokines secreted by cell infection
Chen Yuan   +8 more
doaj   +3 more sources

Persistent Infection of Vero Cells with Tacaribe Virus

open access: yesJournal of General Virology, 1981
Persistently infected cultures have been established from Vero cells surviving primary infection with Tacaribe virus (Vero-T). The growth rate and morphological characteristics of the persistently infected cells were indistinguishable from normal Vero cells.
Elsa Damonte, C E Coto, Celia E Coto
exaly   +3 more sources

Reassortment of high-yield influenza viruses in vero cells and safety assessment as candidate vaccine strains

open access: yesHuman Vaccines & Immunotherapeutics, 2017
Vaccination is the practiced and accessible measure for preventing influenza infection. Because chicken embryos used for vaccine production have various insufficiencies, more efficient methods are needed.
Jian Zhou   +6 more
doaj   +2 more sources

Comparison of anti-SARS-CoV-2 activity and intracellular metabolism of remdesivir and its parent nucleoside

open access: yesCurrent Research in Pharmacology and Drug Discovery, 2021
Remdesivir, a monophosphate prodrug of nucleoside analog GS-441524, is widely used for the treatment of moderate to severe COVID-19. It has been suggested to use GS-441524 instead of remdesivir in the clinic and in new inhalation formulations.
Sijia Tao   +14 more
doaj   +1 more source

Overview of recent advances in Vero cells genomic characterization and engineering for high‐throughput vaccine manufacturing

open access: yesClinical and Translational Discovery, 2022
Background The Vero cell line is the most used continuous cell line for viral vaccine manufacturing with more than 30 years of accumulated experience in the vaccine industry. Nonetheless, virus production yield with Vero cells remains limited. Therefore,
Marie‐Angélique Sène   +2 more
doaj   +1 more source

Construction of a Vero Cell Line Expressing Human ICAM1 for the Development of Rhinovirus Vaccines

open access: yesViruses, 2022
Human rhinoviruses (HRVs) are small non-enveloped RNA viruses that belong to the Enterovirus genus within the Picornaviridae family and are known for causing the common cold.
Wouter Johannes Petrus van den Braak   +5 more
doaj   +1 more source

Growth and Maintenance of Vero Cell Lines [PDF]

open access: yesCurrent Protocols in Microbiology, 2008
AbstractVero cells are derived from the kidney of an African green monkey, and are one of the more commonly used mammalian continuous cell lines in microbiology and molecular and cell biology research. This unit includes protocols for the growth and maintenance of Vero cell lines in a research laboratory setting. Curr. Protoc. Microbiol. 11:A.4E.1‐A.4E.
Nicole C, Ammerman   +2 more
openaire   +2 more sources

Invasion of Vero cells by Salmonella species [PDF]

open access: yesJournal of Medical Microbiology, 1989
The invasiveness of Salmonella strains for Vero cells was studied by quantitative bacteriology; the technique was more sensitive than phase contrast microscopy. All of 59 Salmonella strains, of 19 different serotypes, were more invasive than Escherichia coli K12.
P A, Barrow, M A, Lovell
openaire   +2 more sources

Vero cell invasiveness of Proteus mirabilis [PDF]

open access: yesInfection and Immunity, 1984
Vero cell invasiveness was studied for a group of Proteus mirabilis strains isolated from the urinary tract and feces and for a limited group of urinary isolates of Escherichia coli. Experimental conditions affecting this invasiveness were studied. All of the P. mirabilis strains tested were capable of cell invasion, whereas none of the E. coli strains
P G, Peerbooms   +2 more
openaire   +2 more sources

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