Frontiers in Microbiology, 2022 Porcine epidemic diarrhea virus (PEDV) primarily infects suckling piglets and causes severe economic losses to the swine industry. Cytokines, as part of the innate immune response, are important in PEDV infection. The cytokines secreted by cell infection
Chen Yuan +8 more
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Differential Transcriptional Landscape of Vero Cells During Dengue Virus 2 Infection in the Presence of Sinococuline [PDF]
MicroorganismsDengue virus (DENV) is transmitted by Aedes genus mosquitoes and is responsible for dengue fever (DF) and other severe diseases, posing a significant challenge to the global health system.
Amit Garg +5 more
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Current Research in Pharmacology and Drug Discovery, 2021 Remdesivir, a monophosphate prodrug of nucleoside analog GS-441524, is widely used for the treatment of moderate to severe COVID-19. It has been suggested to use GS-441524 instead of remdesivir in the clinic and in new inhalation formulations.
Sijia Tao +14 more
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Clinical and Translational Discovery, 2022 Background The Vero cell line is the most used continuous cell line for viral vaccine manufacturing with more than 30 years of accumulated experience in the vaccine industry. Nonetheless, virus production yield with Vero cells remains limited. Therefore,
Marie‐Angélique Sène +2 more
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Construction of a Vero Cell Line Expressing Human ICAM1 for the Development of Rhinovirus Vaccines
Viruses, 2022 Human rhinoviruses (HRVs) are small non-enveloped RNA viruses that belong to the Enterovirus genus within the Picornaviridae family and are known for causing the common cold.
Wouter Johannes Petrus van den Braak +5 more
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A Study on the Alteration of Endoplasmic Reticulum Stress-related Proteins in Cyclophosphamide-induced Damage to Urothelium [PDF]
Pharmaceutical and Biomedical Research, 2023 Background: Cyclophosphamide is widely prescribed as an anti-cancer drug and used as an immunosuppressant. Hemorrhagic cystitis is one of the common complications of cyclophosphamide intake.
Hemalatha R +3 more
doaj
High genetic stability of dengue virus propagated in MRC-5 cells as compared to the virus propagated in vero cells. [PDF]
PLoS ONE, 2008 This work investigated the replication kinetics of the four dengue virus serotypes (DEN-1 to DEN-4), including dengue virus type 4 (DEN-4) recovered from an infectious cDNA clone, in Vero cells and in MRC-5 cells grown on Cytodex 1 microcarriers.
Chia-Chyi Liu +3 more
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Responsiveness to basement membrane extract as a possible trait for tumorigenicity characterization
Vaccine: X, 2019 Immortalized cell lines used to produce vaccines are expected to be described in terms of their tumorigenicity. However, current in vivo tumorigenicity assays can be time-consuming and results can be equivocal, especially for weakly tumorigenic cells ...
Haruhiko Murata +7 more
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Differential Effect of Medium on the Ratio of ICM/TE of Bovine Embryos in a Co-culture System [PDF]
International Journal of Fertility and Sterility, 2010 Background This study was undertaken to investigate the efficiency of two different embryo somatic cell co-culture conditions tissue culture medium 199 (TCM199)–vero cells and Menezo B2 (B2)-vero cells for the in vitro developmental quantity and quality ...
Mohsen Forouzanfar +5 more
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Completion of the Entire Hepatitis C Virus Life Cycle in Vero Cells Derived from Monkey Kidney
mBio, 2016 A hepatitis C virus (HCV) cell culture system incorporating the JFH-1 strain and the human hepatoma cell line HuH-7 enabled the production of infectious HCV particles. Several host factors were identified as essential for HCV replication. Supplementation
Asako Murayama +3 more
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