Results 11 to 20 of about 12,029,480 (253)
Vero Cells as a Mammalian Cell Substrate for Human Norovirus [PDF]
Viruses, 2020 Human norovirus (HuNoV) is a principal cause of acute gastroenteritis worldwide, particularly in developing countries. Its global prevalence is underscored by more serious morbidity and some mortality in the young (<5 years) and the elderly. To date, there are no licensed vaccines or approved therapeutics for HuNoV, mostly because there are limited ...
Kyle V Todd +2 more
exaly +6 more sources
A cautionary perspective regarding the isolation and serial propagation of SARS-CoV-2 in Vero cells
npj Vaccines, 2021 An array of SARS-CoV-2 virus variants have been isolated, propagated and used in in vitro assays, in vivo animal studies and human clinical trials. Observations of working stocks of SARS-CoV-2 suggest that sequential propagation in Vero cells leads to ...
Simon G. P. Funnell +16 more
doaj +2 more sources
High genetic stability of dengue virus propagated in MRC-5 cells as compared to the virus propagated in vero cells. [PDF]
PLoS ONE, 2008 This work investigated the replication kinetics of the four dengue virus serotypes (DEN-1 to DEN-4), including dengue virus type 4 (DEN-4) recovered from an infectious cDNA clone, in Vero cells and in MRC-5 cells grown on Cytodex 1 microcarriers.
Chia-Chyi Liu +3 more
doaj +3 more sources
Veterinary Microbiology, 2019 Highlights • Lactobacillus S-layer protein plays an inhibitory role during PEDV infection.• In Vero cells infected with PEDV, apoptosis was mediated by caspase-8/3 activation.• Lactobacillus S-layer protein inhibited PEDV-induced apoptosis in Vero cells.•
Pengcheng Li, Qisheng Zheng, Jibo Hou
exaly +2 more sources
Clinical and Translational Discovery, 2022 Background The Vero cell line is the most used continuous cell line for viral vaccine manufacturing with more than 30 years of accumulated experience in the vaccine industry. Nonetheless, virus production yield with Vero cells remains limited. Therefore,
Marie‐Angélique Sène +2 more
doaj +2 more sources
Frontiers in Microbiology, 2022 Porcine epidemic diarrhea virus (PEDV) primarily infects suckling piglets and causes severe economic losses to the swine industry. Cytokines, as part of the innate immune response, are important in PEDV infection. The cytokines secreted by cell infection
Chen Yuan +8 more
doaj +3 more sources
Virology, 2018 A monkey cell line Vero (ATCC CCL-81) is commonly used for porcine epidemic diarrhea virus (PEDV) propagation in vitro. However, it is still controversial whether the porcine aminopeptidase N (pAPN) counterpart on Vero cells (Vero-APN) confers PEDV entry.
Chun-Miao Ji +2 more
exaly +2 more sources
Vaccine, 2019 Vero cells are nowadays widely used in the production of human vaccines. They are considered as one of the most productive and flexible continuous cell lines available for vaccine manufacturing. However, these cells are anchorage dependent, which greatly
Samia Rourou, Hela Kallel
exaly +2 more sources
Persistent Infection of Vero Cells with Tacaribe Virus
Journal of General Virology, 1981 Persistently infected cultures have been established from Vero cells surviving primary infection with Tacaribe virus (Vero-T). The growth rate and morphological characteristics of the persistently infected cells were indistinguishable from normal Vero cells.
Celia E Coto, Elsa B Damonte
exaly +3 more sources
Completion of the Entire Hepatitis C Virus Life Cycle in Vero Cells Derived from Monkey Kidney
mBio, 2016 A hepatitis C virus (HCV) cell culture system incorporating the JFH-1 strain and the human hepatoma cell line HuH-7 enabled the production of infectious HCV particles. Several host factors were identified as essential for HCV replication. Supplementation
Asako Murayama +3 more
doaj +2 more sources