Results 11 to 20 of about 7,695 (129)
Remdesivir inhibits Porcine epidemic diarrhea virus infection in vitro
Heliyon, 2023 Porcine Epidemic Diarrhea Virus (PEDV) is a highly contagious and pathogenic virus that causes symptoms such as diarrhea, vomiting, weight loss, and even death in piglets. Due to its high transmission rate, PEDV has resulted in significant global losses.
Zi-Xin Huang +4 more
openaire +3 more sources
Molnupiravir Inhibits Porcine Epidemic Diarrhea Virus Infection In Vitro
Viruses, 2023 Porcine epidemic diarrhea virus (PEDV) is a swine coronavirus that is highly infectious and prone to variation. Vaccines derived from traditional PEDV strains provide less protection against PEDV-variant strains. Furthermore; there is a complex diversity of sequences among various PEDV-variant strains.
Zi-Xin Huang +3 more
openaire +3 more sources
ATPase and helicase activities of porcine epidemic diarrhea virus nsp13
Veterinary Microbiology, 2021 Porcine epidemic diarrhea virus (PEDV) is a reemerging Alphacoronavirus that causes lethal diarrhea in piglets. Coronavirus nonstructural protein 13 (nsp13) encodes helicase, which plays pivotal roles during viral replication by unwinding viral RNA. However, the biochemical characterization of PEDV nsp13 remains largely unknown.
Jie Ren +4 more
openaire +3 more sources
Expression and immunogenicity of nsp10 protein of porcine epidemic diarrhea virus
Research in Veterinary Science, 2022 Porcine epidemic diarrhea virus (PEDV), a swine enteropathogenic coronavirus, causes lethal watery diarrhea to the piglets, which poses significant economic losses and public health concerns. The nsp10 protein of PEDV is essential regulatory subunits that are critical for virus replication. Since PEDV nsp10 is a crucial regulator of viral RNA synthesis,
Zhu, Liting +7 more
openaire +2 more sources
Porcine Epidemic Diarrhea Virus and the Host Innate Immune Response [PDF]
Pathogens, 2020 Porcine epidemic diarrhea virus (PEDV), a swine enteropathogenic coronavirus (CoV), is the causative agent of porcine epidemic diarrhea (PED). PED causes lethal watery diarrhea in piglets, which has led to substantial economic losses in many countries and is a great threat to the global swine industry. Interferons (IFNs) are major cytokines involved in
Shasha Li +3 more
openaire +3 more sources
Porcine epidemic diarrhea virus: current insights
Virus Adaptation and Treatment, 2016 Chaochao Lv,1,* Yan Xiao,1,* Xiangdong Li,1 Kegong Tian,1,2 1National Research Center for Veterinary Medicine, Luoyang, People's Republic of China; 2College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou, People's Republic of China *These authors contributed equally to this review Abstract: Porcine ...
Lv,Chaochao +3 more
openaire +4 more sources
Porcine Epidemic Diarrhea Virus
, 2018 Porcine epidemic diarrhea virus (PEDv) causes disease and mortality to piglets worldwide. Most vaccines used to combat the disease have been ineffective live attenuated virus vaccines. Research has emerged showing both the spike (S) and membrane (M) proteins of the virus have potential for use as subunit vaccines.
Khamis, Zayn, Menassa, Rima
openaire +1 more source
Isolation and characterization of a variant porcine epidemic diarrhea virus in China [PDF]
Virology Journal, 2012 AbstractAn outbreak of diarrhea in pigs started in Guangdong, South China in January 2011. Cases were characterized by watery diarrhea, dehydration and vomiting, with 80–100% morbidity and 50–90% mortality in suckling piglets. The causative agent of the diarrhea was ultimately identified as porcine epidemic diarrhea virus (PEDV).
Pan Yongfei +7 more
openaire +3 more sources
A Computationally Designed Serological Assay for Porcine Epidemic Diarrhea Virus [PDF]
Journal of Clinical Microbiology, 2016 ABSTRACT The periodic emergence of new infectious agents and the genetic and antigenic evolution of existing agents necessitate the improvement of technology for the rapid development of diagnostic assays. The porcine epidemic diarrhea virus (PEDV) emerged in the United States in 2013, causing severe economic damage to the pork ...
Yunfeng Song +3 more
openaire +2 more sources
The Redox Properties of Polyphenols and Their Role in ROS Generation for Biomedical Applications
Angewandte Chemie, Volume 138, Issue 3, 16 January 2026.The dual redox nature of polyphenols enables antioxidant activity and controlled reactive oxygen species (ROS) generation. This review details the biomedical applications of polyphenols in materials such as nanoparticles, coatings, and hydrogels for antimicrobial, tissue regeneration, and cancer therapies.
Jose Bolaños‐Cardet +7 more
wiley +2 more sources