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Innate Immune Evasion of Porcine Epidemic Diarrhea Virus Through miRNA-193a-5p/IL22/pBD1 Pathway in Intestinal Epithelium. [PDF]

Transbound Emerg Dis
Feng Q, Chen J, Chen J, Zheng Y, Wu R, Xu L, Wang L, Wang Q.   +7 more
europepmc   +1 more source

Outbreak of Porcine Epidemic Diarrhea Virus in Portugal, 2015 [PDF]

Transboundary and Emerging Diseases, 2015
An outbreak of porcine epidemic diarrhea virus (PEDV) in the South of Portugal in January 2015 and the spread of PEDV northwards in the territory are described. Comparative analysis of the amplified sequences showed a very high (99.0%) identity with the PEDV variant most recently reported in the United States and also show complete (100%) identity to ...
João R Mesquita, W H M Van Der Poel, Maria São José Nascimento   +2 more
exaly   +4 more sources

Cellular entry of the porcine epidemic diarrhea virus

Virus Research, 2016
Porcine epidemic diarrhea virus (PEDV), a coronavirus discovered more than 40 years ago, regained notoriety recently by its devastating outbreaks in East Asia and the Americas, causing substantial economic losses to the swine husbandry. The virus replicates extensively and almost exclusively in the epithelial cells of the small intestine resulting in ...
Wentao Li, Frank J M Van Kuppeveld, Qigai He   +2 more
exaly   +4 more sources

Porcine epidemic diarrhea virus infects and replicates in porcine alveolar macrophages

Virus Research, 2014
Porcine epidemic diarrhea virus (PEDV) is a causative agent of porcine epidemic diarrhea; consequently, the small intestine was believed to be its only target organ. In this study, we found that PEDV infected not only the small intestines, but also the respiratory tract.
Jung-Eun Park, Hyun-Jin Shin
exaly   +3 more sources

Characterization of the porcine epidemic diarrhea virus codon usage bias

Infection, Genetics and Evolution, 2014
Porcine epidemic diarrhea virus (PEDV) has been responsible for several recent outbreaks of porcine epidemic diarrhea (PED) and has caused great economic loss in the swine-raising industry. Considering the significance of PEDV, a systemic analysis was performed to study its codon usage patterns.
Ji-Long Chen, Ting Gu, Chong Wang
exaly   +3 more sources

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Expression and immunogenicity of recombinant porcine epidemic diarrhea virus Nsp9

Virology, 2023
Porcine epidemic diarrhea virus (PEDV) causes acute diarrhea, vomiting, dehydration, and high mortality in newborn piglets, which leads to significant economic losses. Coronavirus nonstructural protein 9 (Nsp9) is an essential RNA binding protein for coronavirus replication, which renders it a promising candidate for developing antiviral drugs and ...
Shiguo Liu, Qijia Yu, Sha Li, Mingzhi Li, Li Yang, Quansheng Wang, Zewen Tu, Feifei Tao, Pingping Yang, Lingbao Kong, Xiu Xin   +10 more
openaire   +2 more sources

Research progress of porcine epidemic diarrhea virus S protein

Frontiers in Microbiology
Porcine epidemic diarrhea virus (PEDV) is a single-stranded RNA virus with a capsid membrane that causes acute infectious gastrointestinal disease characterized by vomiting, diarrhea, and dehydration in swine. Piglets are more susceptible to PEDV than adults, with an infection rate reaching 90% and a fatality rate as high as 100%.
Mengmeng Zhao, Shujian Huang, Lin Junjie   +2 more
exaly   +4 more sources

Rapid quantitation of porcine epidemic diarrhea virus (PEDV) by Virus Counter

Journal of Virological Methods, 2015
Virus Counter was applied for the quantitation of porcine epidemic diarrhea virus (PEDV); the working range and reproducibility of the quantification were characterized, and the performance of Virus Counter was evaluated using the plaque assay as the gold standard.
Xiangbin, Zhang, Jianwei, Hao, Jing, Zhen, Lijuan, Yin, Qianniu, Li, Chunyi, Xue, Yongchang, Cao   +6 more
openaire   +2 more sources

Complete genome characterization of porcine epidemic diarrhea virus in Vietnam

Archives of Virology, 2015
Porcine epidemic diarrhea virus (PEDV) first emerged in Vietnam in 2009. In this study, the complete genomes of three Vietnamese PEDV isolates were characterized. These three isolates were isolated from 3-day-old pigs experiencing diarrhea. Two isolates were from swine farms in the south, and the other was from northern Vietnam.
Dam Thi, Vui, To Long, Thanh, Nguyen, Tung, Anchalee, Srijangwad, Thitima, Tripipat, Taksina, Chuanasa, Dachrit, Nilubol   +6 more
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Characterization and pathogenicity of the porcine epidemic diarrhea virus isolated in China

Microbial Pathogenesis, 2023
Piglet diarrhea caused by the porcine epidemic diarrhea virus (PEDV) is a common problem on pig farms in China associated with high morbidity and mortality rates. In this study, three PEDV isolates were successfully detected after the fourth blind passage in Vero cells.
Tian-Ming, Niu, Ling-Jiao, Yu, Jin-Hui, Zhao, Rong-Rong, Zhang, Emad Beshir, Ata, Nan, Wang, Di, Zhang, Yong-Lei, Yang, Jia-Hao, Qian, Qiao-Dan, Chen, Gui-Lian, Yang, Hai-Bin, Huang, Chun-Wei, Shi, Yan-Long, Jiang, Jian-Zhong, Wang, Xin, Cao, Yan, Zeng, Nan, Wang, Wen-Tao, Yang, Chun-Feng, Wang   +19 more
openaire   +2 more sources