Development and evaluation of an immunochromatographic strip for rapid detection of porcine hemagglutinating encephalomyelitis virus [PDF]
Background The incidence of PHE among pigs in many countries is on the rise, and it has caused great economic losses to the pig industry. Therefore, the development of a sensitive, specific, and easily-performed assay is crucial for the rapid detection ...
Chen Keyan +7 more
doaj +5 more sources
Surveillance of Swine Coronaviruses in Hungarian Herds with a Newly Established Pan-Coronavirus RT-PCR System [PDF]
The rapid evolution of coronaviruses (CoVs) requires researchers to develop specific yet broad-spectrum detection methods to monitor their constant genomic changes.
Dóra Máté +11 more
doaj +2 more sources
Innate Immune Evasion of Porcine Epidemic Diarrhea Virus Through miRNA-193a-5p/IL22/pBD1 Pathway in Intestinal Epithelium. [PDF]
Porcine epidemic diarrhea (PED) virus (PEDV) is a highly contagious intestinal infection that primarily affects suckling pigs. The interaction about the innate immune evasion of PEDV in intestinal epithelium and microRNA (miRNA) remains unclear.
Feng Q +7 more
europepmc +2 more sources
Development and Comparison of Indirect ELISAs for Detecting IgG and IgA Antibodies Against Major Structural Proteins of Porcine Deltacoronavirus With Virus Neutralization as a Benchmark. [PDF]
Porcine deltacoronavirus (PDCoV) is an emerging enteric pathogen that causes substantial economic losses in the global swine industry. Although neutralizing antibodies (NAbs) are a key indicator of vaccine efficacy, their diagnostic concordance with IgG/IgA levels measured by indirect enzyme‐linked immunosorbent assays (iELISAs) targeting major ...
Li D +7 more
europepmc +2 more sources
First detection and characterisation of porcine hemagglutinating encephalomyelitis virus in the Czech Republic [PDF]
Porcine hemagglutinating encephalomyelitis virus (PHEV) is a highly neurovirulent coronavirus that invades the central nervous system in piglets. The incidence of PHEV among pigs in many countries is rising, and the economic losses to the pig industry ...
Romana Moutelikova, Jana Prodelalova
doaj +2 more sources
Progranulin-driven lysosomal acidification facilitates exocytosis of PHEV-hijacked lysosomes for viral release [PDF]
Porcine hemagglutinating encephalomyelitis virus (PHEV) hijacks lysosomes, repurposing them as vehicles for viral release by disrupting their function. Progranulin (PGRN), a lysosomal glycoprotein essential for lysosomal regulation, plays a pivotal role ...
Zhenzhen Wang +11 more
doaj +2 more sources
Seroprevalence of porcine coronavirus antibodies in Iberian pigs and wild boars from central-western Spain [PDF]
Porcine coronaviruses (PoCoVs) are common etiological viral agents of enteric and respiratory disease in swine, but most epidemiological information derives from intensively managed herds. Data from outdoor systems and wildlife remain scarce, despite the
Paloma Encinas +9 more
doaj +2 more sources
Newly identified lineages of porcine hemagglutinating encephalomyelitis virus exhibit respiratory phenotype. [PDF]
Abstract Swine pathogens have a long history of zoonotic transmission to humans, occasionally leading to sustained outbreaks or pandemics. Through a retrospective epidemiological study of swine populations in China, we describe novel lineages of porcine hemagglutinating encephalomyelitis virus (PHEV) complex coronaviruses (CoVs) that ...
He WT +11 more
europepmc +5 more sources
Porcine Hemagglutinating Encephalomyelitis Virus Triggers Neural Autophagy Independently of ULK1. [PDF]
The ongoing coronavirus disease 2019 (COVID-19) pandemic alongside the outbreaks of severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS) pose Betacoronavirus (β-CoV) as a global public health challenge.
Li Z +7 more
europepmc +3 more sources
Porcine Hemagglutinating Encephalomyelitis Virus Infection In Vivo and Ex Vivo. [PDF]
Among the ∼46 virus species in the familyCoronaviridae(2019), many of which are important pathogens of humans and 6 of which are commonly found in pigs, porcine hemagglutinating encephalomyelitis remains one of the least researched. The present study provided a comprehensive characterization of the PHEV infection process and immune responses using CDCD
Mora-Díaz JC +10 more
europepmc +4 more sources

