Results 11 to 20 of about 1,158,020 (134)

The evidence of porcine hemagglutinating encephalomyelitis virus induced nonsuppurative encephalitis as the cause of death in piglets [PDF]

PeerJ, 2016
An acute outbreak of porcine hemagglutinating encephalomyelitis virus (PHEV) infection in piglets, characterized with neurological symptoms, vomiting, diarrhea, and wasting, occurred in China.
Zi Li, Wenqi He, Yungang Lan, Kui Zhao, Xiaoling Lv, Huijun Lu, Ning Ding, Jing Zhang, Junchao Shi, Changjian Shan, Feng Gao   +10 more
doaj   +8 more sources

Newly identified lineages of porcine hemagglutinating encephalomyelitis virus exhibit respiratory phenotype. [PDF]

Virus Evolution, 2023
Abstract Swine pathogens have a long history of zoonotic transmission to humans, occasionally leading to sustained outbreaks or pandemics. Through a retrospective epidemiological study of swine populations in China, we describe novel lineages of porcine hemagglutinating encephalomyelitis virus (PHEV) complex coronaviruses (CoVs) that ...
Edward C. Holmes, Marc A. Suchard, Guy Baele   +2 more
exaly   +8 more sources

Porcine Hemagglutinating Encephalomyelitis Virus Infection In Vivo and Ex Vivo. [PDF]

J Virol, 2021
Among the ∼46 virus species in the familyCoronaviridae(2019), many of which are important pathogens of humans and 6 of which are commonly found in pigs, porcine hemagglutinating encephalomyelitis remains one of the least researched. The present study provided a comprehensive characterization of the PHEV infection process and immune responses using CDCD
Mora-Díaz JC, Piñeyro PE, Rauh R, Nelson W, Sankoh Z, Gregg E, Carrillo-Ávila JA, Shen H, Nelli RK, Zimmerman JJ, Giménez-Lirola LG.   +10 more
europepmc   +6 more sources

Development and evaluation of an immunochromatographic strip for rapid detection of porcine hemagglutinating encephalomyelitis virus [PDF]

Virology Journal, 2012
Background The incidence of PHE among pigs in many countries is on the rise, and it has caused great economic losses to the pig industry. Therefore, the development of a sensitive, specific, and easily-performed assay is crucial for the rapid detection ...
Chen Keyan, Zhao Kui, Song Deguang, He Wenqi, Gao Wei, Zhao Chuanbo, Wang Chengli, Gao Feng   +7 more
doaj   +5 more sources

First Detection of Porcine Hemagglutinating Encephalomyelitis Virus (PHEV) in Wild Boars (Sus scrofa) from Southern Italy: A Two-Year Epidemiological Survey [PDF]

Veterinary Sciences
In recent years, the wild boar population has increased in Italy. Wild boar is one of the most problematic species from a sanitary point of view because it represents a dangerous reservoir of pathogens and viruses.
Chiara Ortello, Viviana Manzulli, Lorenzo Pace, Antonella Cristina Romano, Mariateresa Toce, Lucia Palazzo, Donatella Farina, Laura Del Sambro, Valeria Rondinone, Luigina Serrecchia, Domenico Galante   +10 more
doaj   +3 more sources

Porcine coronavirus promotes NLRP3 inflammasome activation during virus-induced neuroinflammation [PDF]

mBio
Neurotropic coronaviruses can invade the central nervous system (CNS) and cause severe neurological disease, but the mechanisms underlying virus-induced neuroinflammation remain incompletely understood.
Qianyu Zhou, Junchao Shi, Ruizhao Qiu, Rui Dai, Yungang Lan, Jiyong Zhou, Xuming Deng, Wenqi He, Zi Li   +8 more
doaj   +3 more sources

Porcine Hemagglutinating Encephalomyelitis Virus Triggers Neural Autophagy Independently of ULK1. [PDF]

Journal of Virology, 2021
The ongoing coronavirus disease 2019 (COVID-19) pandemic alongside the outbreaks of severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS) pose Betacoronavirus (β-CoV) as a global public health challenge.
Jiyu Guan, Feng Gao, Kui Zhao
exaly   +4 more sources

Porcine Hemagglutinating Encephalomyelitis Virus Enters Neuro-2a Cells via Clathrin-Mediated Endocytosis in a Rab5-, Cholesterol-, and pH-Dependent Manner. [PDF]

Journal of Virology, 2017
Porcine hemagglutinating encephalomyelitis virus (PHEV) is a highly neurovirulent coronavirus that invades the central nervous system (CNS) in piglets.
Feng Gao, Kui Zhao, Zi Li
exaly   +3 more sources

Ulk1 Governs Nerve Growth Factor/TrkA Signaling by Mediating Rab5 GTPase Activation in Porcine Hemagglutinating Encephalomyelitis Virus-Induced Neurodegenerative Disorders. [PDF]

Journal of Virology, 2018
Porcine hemagglutinating encephalomyelitis virus (PHEV) is a neurotropic coronavirus and targets neurons in the nervous system for proliferation, frequently leaving behind grievous neurodegeneration.
Feng Gao, Kui Zhao, Zi Li
exaly   +3 more sources

An Experimental Model of Neurodegenerative Disease Based on Porcine Hemagglutinating Encephalomyelitis Virus–Related Lysosomal Abnormalities [PDF]

Molecular Neurobiology, 2020
Lysosomes are involved in pathogenesis of a variety of neurodegenerative diseases and play a large role in neurodegenerative disorders caused by virus infection. However, whether virus-infected cells or animals can be used as experimental models of neurodegeneration in humans based on virus-related lysosomal dysfunction remain unclear.
Feng Gao, Kui Zhao, Yungang Lan
exaly   +6 more sources