Results 71 to 80 of about 1,158,020 (134)

Endoplasmic reticulum stress in diseases

MedComm, Volume 5, Issue 9, September 2024.
The endoplasmic reticulum (ER) serves as a vital organelle in eukaryotic cells, performing essential roles such as protein folding, modification, and trafficking, lipid biosynthesis, and calcium regulation. Various conditions may disrupt ER function, potentially leading to the accumulation of unfolded and misfolded proteins, and triggering ER stress ...
Yingying Liu, Chunling Xu, Renjun Gu, Ruiqin Han, Ziyun Li, Xianrong Xu   +5 more
wiley   +1 more source

Limited availability of methods for the detection of xenotransplantation‐relevant viruses in veterinary laboratories

Xenotransplantation, Volume 31, Issue 3, May/June 2024.
Abstract Background The German Xenotransplantation Consortium is in the process to prepare a clinical trial application (CTA) on xenotransplantation of genetically modified pig hearts. In the CTA documents to the central and national regulatory authorities, that is, the European Medicines Agency (EMA) and the Paul Ehrlich Institute (PEI), respectively,
Joachim Denner
wiley   +1 more source

Cross‐Correlation between Biosecurity Measures and the Detection of Viral and Bacterial Agents on German Farms with Respiratory Disease

Transboundary and Emerging Diseases, Volume 2024, Issue 1, 2024.
Effective porcine health management relies majorly on diagnostic tests, vaccination, treatment strategies, and a proper biosecurity management plan. However, understanding the link between circulating microbes and biosecurity measures on a pig farm is not evident.
Julia Stadler, Kathrin Lillie-Jaschniski, Sophia Zwickl, Susanne Zoels, Sebastiaan Theuns, Mathias Ritzmann, Nick Vereecke, Jordi Casal   +7 more
wiley   +1 more source

Development of Reverse Transcriptase PCR and Nested PCR to Detect Porcine Hemagglutinating Encephalomyelitis Virus

Journal of Veterinary Medical Science, 2004
Porcine hemagglutinating encephalomyelitis virus (HEV) causes encephalomyelitis, or vomiting and wasting disease, in suckling piglets. The mortality rate for piglets under 3 weeks old is 100%, but they are usually protected by maternal antibodies. Recently, the risk of an HEV outbreak has increased in the pig industry, because of widely using specific ...
SEKIGUCHI, Yoshiko, SHIRAI, Junsuke, TANIGUCHI, Takahide, HONDA, Eiichi   +3 more
openaire   +3 more sources

Viable porcine arteriviruses with deletions proximal to the 3 ' end of the genome [PDF]

, 2001
In order to obtain attenuated live vaccine candidates of porcine reproductive and respiratory syndrome virus (PRRSV), a series of deletions was introduced at the 3′ end of the viral genome using an infectious cDNA clone of the Lelystad virus isolate. RNA
Rottier, P.J.M., Meulenberg, J.J.M., Verheije, M.H., Kroese, M.V.   +3 more
core  

IDENTIFICATION AND GENETIC CHARACTERIZATION OF PORCINE HEMAGGLUTINATING ENCEPHALOMYELITIS VIRUS IN RUSSIA

PIG-BREEDING
Swine coronaviruses (SCoVs), comprising members of the genera Alphacoronavirus, Betacoronavirus, and Deltacoronavirus, include several important pathogens responsible for economically significant diseases in pigs. Among them, porcine hemagglutinating encephalomyelitis virus (PHEV), a betacoronavirus, represents a potential threat to swine health ...
T.D. MUSAEVA, E.B. SHAITAROVA, N.D. YOLSHIN, D.M. DANILENKO, E.V. STOLBOV, V.V. PRUGLO, D.A. LIOZNOV, A.V. KOMISSAROV   +7 more
openaire   +1 more source

Kissing interaction between 3' noncoding and coding sequences is essential for porcine arterivirus RNA replication [PDF]

, 2002
We used an infectious cDNA clone of Porcine reproductive and respiratory syndrome virus (PRRSV) to investigate the presence of essential replication elements in the region of the genome encoding the structural proteins.
R. C. L. Olsthoorn, Rottier, P.J.M., J. J. M. Meulenberg, Olsthoorn, R.R.C.L., M. H. Verheije, P. J. M. Rottier, M. V. Kroese, Meulenberg, J.J.M., Verheije, M.H., Olsthoorn, R.C.L., Kroese, M.V.   +10 more
core   +1 more source

The neurovirulent GDVII strain of Theiler's virus can replicate in glial cells [PDF]

, 1995
The distribution, spread, neuropathology, tropism, and persistence of the neurovirulent GDVII strain of Theiler's virus in the central nervous system (CNS) was investigated in mice susceptible and resistant to chronic demyelinating infection with TO ...
Dyson, H, Fazakerley, J K, Simas, J P
core  

Virus demyelination [PDF]

, 2003
A number of viruses can initiate central nervous system (CNS) diseases that include demyelination as a major feature of neuropathology. In humans, the most prominent demyelinating diseases are progressive multifocal leukoencephalopathy, caused by JC ...
Fazakerley, John K, Walker, Robert
core   +1 more source

Australian porcine circoviruses [PDF]

, 2006
Two types of porcine circovirus (PCV) exist, referred to as PCV1 and PCV2. PCV2 has been associated with disease syndromes in pigs, including that designated postweaning multisystemic wasting syndrome (PMWS), which has been identified in all regions of ...
Muhling, Jill
core