Results 1 to 10 of about 18,806 (138)

TLR/MyD88-Mediated Inflammation Induced in Porcine Intestinal Epithelial Cells by Ochratoxin A Affects Intestinal Barrier Function [PDF]

Toxics, 2023
The intestinal epithelium performs vital functions such as nutrient absorption and acting as an intestinal barrier to maintain the host’s homeostasis. Mycotoxin, which affects the processing and storage of animal feedstuff, is a problematic pollutant in ...
Jung Woong Yoon, Sangsu Shin, JeongWoong Park, Bo Ram Lee, Sang In Lee   +4 more
doaj   +4 more sources

Metabolomic and Proteomic Profiling of Porcine Intestinal Epithelial Cells Infected with Porcine Epidemic Diarrhea Virus. [PDF]

Int J Mol Sci, 2023
Porcine epidemic diarrhea virus (PEDV) infection results in severe epidemic diarrhea and the death of suckling pigs. Although new knowledge about the pathogenesis of PEDV has been improved, alterations in metabolic processes and the functional regulators involved in PEDV infection with host cells remain largely unknow.
Wang H, Hui P, Uemoto Y, Ding Y, Yin Z, Bao W.   +5 more
europepmc   +3 more sources

Lactobacillus gasseri LA39 Activates the Oxidative Phosphorylation Pathway in Porcine Intestinal Epithelial Cells [PDF]

Frontiers in Microbiology, 2018
Intestinal microbial interactions with the host epithelium have important roles in host health. Our previous data have suggested that Lactobacillus gasseri LA39 is the predominant intestinal Lactobacillus in weaned piglets.
Jun Hu, Jun Hu, Jun Hu, Libao Ma, Libao Ma, Libao Ma, Wenyong Zheng, Wenyong Zheng, Wenyong Zheng, Yangfan Nie, Yangfan Nie, Yangfan Nie, Xianghua Yan, Xianghua Yan, Xianghua Yan   +14 more
doaj   +5 more sources

A Functional Variant in the Aquaporin-3 Promoter Modulates Its Expression and Correlates With Resistance to Porcine Epidemic Virus Infection in Porcine Intestinal Epithelial Cells [PDF]

Frontiers in Microbiology, 2022
Porcine epidemic diarrhea virus (PEDV) causes a highly contagious intestinal disease in neonatal pigs. Aquaporin-3 (AQP3) plays important roles in maintenance of intestinal barrier function and regulation of immune responses.
Haifei Wang, Zhenbin Bi, Kaiyu Dai, Pinghua Li, Ruihua Huang, Shenglong Wu, Shenglong Wu, Wenbin Bao, Wenbin Bao   +8 more
doaj   +2 more sources

4'-Hydroxydehydrokawain Mitigate the Cytotoxicity of Citrinin in Porcine Intestinal Epithelial Cells. [PDF]

Toxics
Citrinin (CTN) is a mycotoxin that adversely affects livestock by contaminating stored grains, leading to significant health and economic impacts. This study investigates the toxicological effects of CTN on porcine small intestinal epithelial cells (IPEC-J2) and explores potential mitigation strategies using natural products and chemical inhibitors ...
Lim SJ, Shin S, Lee SI.
europepmc   +4 more sources

Antioxidant Activity of Flavonoids in LPS-Treated IPEC-J2 Porcine Intestinal Epithelial Cells and Their Antibacterial Effect against Bacteria of Swine Origin [PDF]

Antioxidants, 2020
Beneficial effects of flavonoids are widely known in human medicine, but less information is available about their veterinary usage. Based on their antioxidant and antibacterial activity, proanthocyanidins (PAs) and luteolin (LUT) might be used in the ...
Dóra Kovács, Zita Karancsi, Orsolya Farkas, Ákos Jerzsele   +3 more
doaj   +2 more sources

Transcriptome and chromatin accessibility in porcine intestinal epithelial cells upon Zearalenone exposure. [PDF]

Sci Data, 2019
AbstractZearalenone (ZEA) is one of the main mycotoxins widely spread in contaminated cereal crops, which poses a great threat to food safety as well as human and animal health. Biological control strategies are emerging as important solutions to eliminate mycotoxin contaminations. However, molecular mechanisms underlying ZEA cytotoxic effects are only
Wang H, Jin J, Wu J, Qu H, Wu S, Bao W.
europepmc   +4 more sources

Comprehensive mapping of the cell response to E. coli infection in porcine intestinal epithelial cells pretreated with exopolysaccharide derived from Lactobacillus reuteri [PDF]

Veterinary Research, 2020
Bacterial exopolysaccharides (EPSs) are known to modulate immunity. To date, a plethora of studies have reported the effect of EPSs on intestinal cells; however few works have revealed a complete picture of the signalling events in intestinal epithelial ...
Ľudmila Tkáčiková, Evelína Mochnáčová, Punit Tyagi, Zuzana Kiššová, Mangesh Bhide   +4 more
doaj   +2 more sources

Surface-Displayed Porcine IFN-λ3 in Lactobacillus plantarum Inhibits Porcine Enteric Coronavirus Infection of Porcine Intestinal Epithelial Cells. [PDF]

J Microbiol Biotechnol, 2020
Interferon (IFN)-λ plays an essential role in mucosal cells which exhibit strong antiviral activity. Lactobacillus plantarum (L. plantarum) has substantial application potential in the food and medical industries because of its probiotic properties. Alphacoronaviruses, especially porcine epidemic diarrhea virus (PEDV) and transmissible gastroenteritis ...
Liu YS, Liu Q, Jiang YL, Yang WT, Huang HB, Shi CW, Yang GL, Wang CF.   +7 more
europepmc   +4 more sources

Profile analysis of circRNAs induced by porcine endemic diarrhea virus infection in porcine intestinal epithelial cells. [PDF]

Virology, 2019
The circRNA is a newly defined noncoding RNA and characterized by its unique splicing reactions to form circles. However, the function of circRNAs during viral infection remains largely unknown. In this study, the circRNA expression profile during porcine endemic diarrhea virus (PEDV) infection in IPEC-J2 cell line was investigated using the next ...
Chen J, Wang H, Jin L, Wang L, Huang X, Chen W, Yan M, Liu G.   +7 more
europepmc   +3 more sources