Binding Studies on Isolated Porcine Small Intestinal Mucosa and in vitro Toxicity Studies Reveal Lack of Effect of C. perfringens Beta-Toxin on the Porcine Intestinal Epithelium [PDF]
Toxins, 2015 Beta-toxin (CPB) is the essential virulence factor of C. perfringens type C causing necrotizing enteritis (NE) in different hosts. Using a pig infection model, we showed that CPB targets small intestinal endothelial cells.
Simone Roos +6 more
doaj +4 more sources
Viruses, 2021 Porcine deltacoronavirus (PDCoV) is an emerging infectious disease of swine with zoonotic potential. Phylogenetic analysis suggests that PDCoV originated recently from a host-switching event between birds and mammals.
Diana Cruz-Pulido +5 more
doaj +3 more sources
Lactobacillus gasseri LA39 Activates the Oxidative Phosphorylation Pathway in Porcine Intestinal Epithelial Cells [PDF]
Frontiers in Microbiology, 2018 Intestinal microbial interactions with the host epithelium have important roles in host health. Our previous data have suggested that Lactobacillus gasseri LA39 is the predominant intestinal Lactobacillus in weaned piglets.
Jun Hu +14 more
doaj +2 more sources
Toxins, 2015 The intestinal epithelium is the first barrier against food contaminants. Zearalenone (ZEN) is an estrogenic mycotoxin that was identified as a common contaminant of cereal grains and food and feedstuffs.
Daniela E. Marin +2 more
doaj +2 more sources
Transcriptome and chromatin accessibility in porcine intestinal epithelial cells upon Zearalenone exposure. [PDF]
Sci Data, 2019 This dataset present the mRNA, miRNA, lncRNA, and chromatin accessibility sequencing data of porcine intestinal epithelial cells upon zearalenone ...
Wang H, Jin J, Wu J, Qu H, Wu S, Bao W.
europepmc +2 more sources
Characteristic and functional analysis of a newly established porcine small intestinal epithelial cell line. [PDF]
PLoS ONE, 2014 The mucosal surface of intestine is continuously exposed to both potential pathogens and beneficial commensal microorganisms. Recent findings suggest that intestinal epithelial cells, which once considered as a simple physical barrier, are a crucial cell
Jing Wang +5 more
doaj +1 more source
Communications Biology, 2022 When piglets are infected with intestinal virus, porcine intraepithelial lymphocytes undergo intra-and trans-epithelial migration promoted by chemokines from infected epithelial cells and produce an antiviral response.
Yuchen Li +8 more
doaj +1 more source
A Selected Lactobacillus rhamnosus Strain Promotes EGFR-Independent Akt Activation in an Enterotoxigenic Escherichia coli K88-Infected IPEC-J2 Cell Model. [PDF]
PLoS ONE, 2015 Enterotoxigenic Escherichia coli (ETEC) are important intestinal pathogens that cause diarrhea in humans and animals. Although probiotic bacteria may protect against ETEC-induced enteric infections, the underlying mechanisms are unknown.
Wei Zhang +5 more
doaj +1 more source
Physiological Concentration of Exogenous Lactate Reduces Antimycin A Triggered Oxidative Stress in Intestinal Epithelial Cell Line IPEC-1 and IPEC-J2 In Vitro. [PDF]
PLoS ONE, 2016 Weaning triggers an adaptation of the gut function including luminal lactate generation by lactobacilli, depending on gastrointestinal site. We hypothesized that both lactobacilli and lactate influence porcine intestinal epithelial cells.
Stefan Kahlert +11 more
doaj +1 more source
Cell lineage identification and stem cell culture in a porcine model for the study of intestinal epithelial regeneration. [PDF]
PLoS ONE, 2013 Significant advances in intestinal stem cell biology have been made in murine models; however, anatomical and physiological differences between mice and humans limit mice as a translational model for stem cell based research.
Liara M Gonzalez +4 more
doaj +1 more source