Results 1 to 10 of about 10,162 (212)
PEDV-spike-protein-expressing mRNA vaccine protects piglets against PEDV challenge
MBioPorcine epidemic diarrhea virus (PEDV), a swine enteropathogenic coronavirus, causes severe diarrhea in neonatal piglets, which is associated with a high mortality rate.
Baochao Fan, Bin Li
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Expression and Purification of a PEDV-Neutralizing Antibody and Its Functional Verification
Viruses, 2021 Porcine epidemic diarrhea virus (PEDV) is a highly infectious and pathogenic virus causing high morbidity and mortality, especially in newborn piglets. There remain problems with contemporary PEDV vaccines, in part because of the rapid variation of PEDV,
Yaning Hu, Xingbo Zhao
exaly +3 more sources
Viruses, 2020 The genomes of coronaviruses carry accessory genes known to be associated with viral virulence. The single accessory gene of porcine epidemic diarrhea virus (PEDV), ORF3, is dispensable for virus replication in vitro, while viral mutants carrying ORF3 ...
Fusheng Si, Zhen Li
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Novel Neutralizing Epitope of PEDV S1 Protein Identified by IgM Monoclonal Antibody
Viruses, 2022 Porcine epidemic diarrhea virus (PEDV) causes devastating enteric disease that inflicts huge economic damage on the swine industry worldwide. A safe and highly effective PEDV vaccine that contains only the virus-neutralizing epitopes (not enhancing ...
Techit Thavorasak +2 more
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A monoclonal antibody-based electrochemical immunosensor for porcine epidemic diarrhea virus [PDF]
Applied Microbiology and BiotechnologyThis study reports the development of a novel and highly sensitive electrochemical immunosensor for detecting porcine epidemic diarrhea virus (PEDV). To this end, a unique PEDV spike protein–specific monoclonal antibody (mAb) was generated and evaluated ...
Wenjie Li +5 more
doaj +2 more sources
Resistance of Field-Isolated Porcine Epidemic Diarrhea Virus to Interferon and Neutralizing Antibody
Veterinary Sciences, 2022 Variant porcine epidemic diarrhea virus (PEDV), belonging to the genogroup G2b, has higher pathogenicity and mortality than classical PEDV, belonging to the genogroup G1a.
Jung-Eun Park, Hyun-Jin Shin
doaj +1 more source
Frontiers in Immunology, 2021 Porcine epidemic diarrhea (PED) is an acute, highly contagious intestinal swine disease caused by porcine epidemic diarrhea virus (PEDV). In addition to known PEDV infection targets (villous small intestinal epithelial cells), recent reports suggest that
Jie Wang +15 more
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Veterinary Quarterly, 2020 Background Outbreaks of porcine epidemic diarrhea virus (PEDV) infection have re-emerged and spread rapidly worldwide, resulting in significant economic losses. Vaccination is the best way to prevent PEDV infection in young piglets.
Jung-Eun Park +4 more
doaj +1 more source
Porcine epidemic diarrhea virus RNA present in commercial spray-dried porcine plasma is not infectious to naïve pigs. [PDF]
PLoS ONE, 2014 Porcine epidemic diarrhea virus emerged in North America in April 2013 and has since been identified in 30 U.S. States, Canada and Mexico. The rapid spread of PEDV has raised concerns about the role of feed and particularly pork-by-product components ...
Tanja Opriessnig +4 more
doaj +1 more source
Viruses, 2023 Various coronaviruses have emerged as a result of cross-species transmission among humans and domestic animals. Porcine epidemic diarrhea virus (PEDV; family Coronaviridae, genus Alphacoronavirus) causes acute diarrhea, vomiting, dehydration, and high ...
Zheng Niu +12 more
doaj +1 more source