Results 21 to 30 of about 6,592 (133)

Levistolide A Inhibits PEDV Replication via Inducing ROS Generation

Viruses, 2022
Porcine epidemic diarrhea virus (PEDV) variant strains adversely affect the production of pigs globally. Vaccines derived from PEDV traditional strains impart less protection against the variant strains.
Wei Zeng, Jingping Ren, Zhonghua Li, Changsheng Jiang, Qi Sun, Chang Li, Wan Li, Wentao Li, Qigai He   +8 more
doaj   +1 more source

Analysis of Swine Conventional Dendritic Cells, DEC205⁺CD172a^+/−CADM1⁺, from Blood and Spleen in Response to PRRSV and PEDV

Viruses, 2019
Conventional dendritic cells (cDCs) cannot be infected by porcine reproductive and respiratory syndrome virus (PRRSV) but respond to infection via cytokine production, indicating a possible role in initiation/regulation of the immune response against ...
Héctor Parra-Sánchez, Lorena Bustamante-Córdova, Mónica Reséndiz, Verónica Mata-Haro, Araceli Pinelli-Saavedra, Jesús Hernández   +5 more
doaj   +1 more source

Fangchinoline inhibits the PEDV replication in intestinal epithelial cells via autophagic flux suppression

Frontiers in Microbiology, 2023
Animal and human health are severely threatened by coronaviruses. The enteropathogenic coronavirus, porcine epidemic diarrhea virus (PEDV), is highly contagious, leading to porcine epidemic diarrhea (PED), which causes large economic losses in the world ...
Weixiao Zhang, Weixiao Zhang, Haiyan Shen, Haiyan Shen, Menglu Wang, Menglu Wang, Xuelei Fan, Xuelei Fan, Songqi Wang, Songqi Wang, Nile Wuri, Nile Wuri, Bin Zhang, Bin Zhang, Haiyan He, Haiyan He, Chunhong Zhang, Chunhong Zhang, Zhicheng Liu, Zhicheng Liu, Ming Liao, Ming Liao, Jianfeng Zhang, Jianfeng Zhang, Yugu Li, Jianmin Zhang   +25 more
doaj   +1 more source

Preparation and characterisation of monoclonal antibodies against the N protein of the SHpd/2012 strain of porcine epidemic diarrhoea virus

Veterinární Medicína, 2018
Porcine epidemic diarrhoea is caused by the porcine epidemic diarrhoea virus, and is a highly contagious disease which affects the intestines of new-born piglets resulting in intense diarrhoea.
S.J. Ding, Y.R. Luo, S.T. Zhou, C. Xie, K. Wang, Y.Y. Xie, L. Cui, X.G. Hua, C.L. Yuan, Y.J. Zhou, Z.B. Yang   +10 more
doaj   +1 more source

Investigation of the Role of the Spike Protein in Reversing the Virulence of the Highly Virulent Taiwan Porcine Epidemic Diarrhea Virus Pintung 52 Strains and Its Attenuated Counterpart

Viruses, 2019
Porcine epidemic diarrhea virus (PEDV) has continuously caused severe economic losses to the global swine industries; however, no successful vaccine against PEDV has been developed.
Chi-Fei Kao, Hui-Wen Chang
doaj   +1 more source

Inactivated Pseudomonas PE(ΔIII) exotoxin fused to neutralizing epitopes of PEDV S proteins produces a specific immune response in mice

Animal Diseases, 2021
Porcine epidemic diarrhea (PED) caused by the porcine epidemic diarrhea virus (PEDV), is a severe infectious and devastating swine disease that leads to serious economic losses in the swine industry worldwide.
Leqiang Sun, Yajie Tang, Keji Yan, Huanchun Chen, Huawei Zhang   +4 more
doaj   +1 more source

Selective protease inhibitors from secondary metabolites of Philippine medicinal plants against porcine epidemic diarrhea virus: A computational veterinary drug discovery approach

Open Veterinary Journal
Background: Porcine epidemic diarrhea virus (PEDV) is a recurring coronavirus that causes severe diarrhea in pigs with high mortality and morbidity rates, especially in neonatal pigs. Despite the availability of vaccines, their efficacy is limited owing
John Christian C. de Guzman, Albert Neil G. Dulay, Fredmoore L. Orosco   +2 more
doaj   +1 more source

RNASEK interacting with PEDV structural proteins facilitates virus entry via clathrin-mediated endocytosis

Journal of Virology
Porcine epidemic diarrhea virus (PEDV), as a type of Alphacoronavirus causing acute diarrhea and high death rate among sucking piglets, poses great financial damage to the swine industry.
Wenzhen Qin, Ning Kong, Shengsong Xie, Hailong Liu, Xinyu Yang, Yahe Wang, Xinyu Cao, Yuchang Liu, Jiarui Wang, He Sun, Wu Tong, Hai Yu, Hao Zheng, Wen Zhang, Guangzhi Tong, Tongling Shan   +15 more
doaj   +1 more source

Growth enhancement of porcine epidemic diarrhea virus (PEDV) in Vero E6 cells expressing PEDV nucleocapsid protein.

PLoS ONE, 2019
More recently emerging strains of porcine epidemic diarrhea virus (PEDV) cause severe diarrhea and especially high mortality rates in infected piglets, leading to substantial economic loss to worldwide swine industry.
Benjamas Liwnaree, Jaraspim Narkpuk, Suttipun Sungsuwan, Anan Jongkaewwattana, Peera Jaru-Ampornpan   +4 more
doaj   +1 more source

RSL3 Inhibits Porcine Epidemic Diarrhea Virus Replication by Activating Ferroptosis

Viruses, 2023
Porcine epidemic diarrhea virus (PEDV) is a highly contagious coronavirus that induces diarrhea and death in neonatal piglets, resulting in substantial economic losses to the global swine industry.
Yingguang Li, Yuwei Bao, Yan Li, Xiaoxiao Duan, Shaoming Dong, Jiaxu Lin, Xiaoyun Chang, Yue Tan, Hongliang Zhang, Hu Shan   +9 more
doaj   +1 more source