Results 11 to 20 of about 10,162 (212)

Growth enhancement of porcine epidemic diarrhea virus (PEDV) in Vero E6 cells expressing PEDV nucleocapsid protein.

PLoS ONE, 2019
More recently emerging strains of porcine epidemic diarrhea virus (PEDV) cause severe diarrhea and especially high mortality rates in infected piglets, leading to substantial economic loss to worldwide swine industry.
Benjamas Liwnaree, Jaraspim Narkpuk, Suttipun Sungsuwan, Anan Jongkaewwattana, Peera Jaru-Ampornpan   +4 more
doaj   +4 more sources

The Pseudotyped Replication-Deficient VSV with Spike from PEDV Induces Neutralizing Antibody Against PEDV

Vaccines
Background: Porcine epidemic diarrhea virus (PEDV) is a significant pathogen in swine, causing substantial economic losses worldwide. Despite the availability of existing vaccines, there is a critical need for novel vaccine platforms that ensure robust ...
Jingxuan Yi, Huaye Luo, Kang Zhang, Lilei Lv, Siqi Li, Yifeng Jiang, Yanjun Zhou, Zuzhang Wei, Changlong Liu   +8 more
doaj   +3 more sources

Levistolide A Inhibits PEDV Replication via Inducing ROS Generation [PDF]

Viruses, 2022
Porcine epidemic diarrhea virus (PEDV) variant strains adversely affect the production of pigs globally. Vaccines derived from PEDV traditional strains impart less protection against the variant strains.
Wei Zeng, Jingping Ren, Zhonghua Li, Changsheng Jiang, Qi Sun, Chang Li, Wan Li, Wentao Li, Qigai He   +8 more
doaj   +3 more sources

Discovery of Cetaben as a Novel Antiviral Agent Against Porcine Epidemic Diarrhea Virus From a Cholesterol-Lowering Compound Library. [PDF]

Transbound Emerg Dis
The devastating impact of porcine epidemic diarrhea virus (PEDV) on the global swine industry underscores an urgent need for effective antiviral therapies. Drug repurposing presents a promising strategy to accelerate the development of such treatments.
Li Y, Qin P, Zhang K, Ma N, Wang T, Chen Z, Yuan Y, Li D, Yu L, Li W, Du W, Li Y.   +11 more
europepmc   +2 more sources

Emergence of a Highly Virulent Porcine Epidemic Diarrhea Virus (PEDV) G2c Subtype in China: Isolation, Genetic and Pathogenic Characterization, and Cross-Neutralizing Antibody Response. [PDF]

Transbound Emerg Dis
Porcine epidemic diarrhea virus (PEDV), an enteropathogenic coronavirus causing high mortality in neonatal piglets, continues to threaten global swine industries. Frequent mutations in the spike (S) protein of PEDV, particularly in emerging variants, have substantially compromised commercial vaccine efficacy.
Li YY, Fan CH, Li HX, Zhen HQ, Zhu YQ, Wang S, Wang B, Huang YW.   +7 more
europepmc   +2 more sources

Natural Products as Potential Resource Library for Control of Major Swine Enteric Viruses. [PDF]

Transbound Emerg Dis
Major swine enteric viruses (SEVs), including porcine epidemic diarrhea virus (PEDV), porcine deltacoronavirus (PDCoV), transmissible gastroenteritis virus (TGEV), swine acute diarrhea syndrome coronavirus (SADS‐CoV), and porcine rotavirus (PoRV), cause severe gastrointestinal diseases in pigs, leading to huge economic losses to the swine industry ...
Zhang J, Liu Y, Ren S, Wang Z, Li Y, Peng L, Fang R.   +6 more
europepmc   +2 more sources

Enhancing epitope of PEDV spike protein

Frontiers in Microbiology, 2022
Porcine epidemic diarrhea virus (PEDV) is the causative agent of a highly contagious enteric disease of pigs characterized by diarrhea, vomiting, and severe dehydration. PEDV infects pigs of all ages, but neonatal pigs during the first week of life are highly susceptible; the mortality rates among newborn piglets may reach 80–100%.
Techit Thavorasak, Techit Thavorasak, Monrat Chulanetra, Kittirat Glab-ampai, Kodchakorn Mahasongkram, Nawannaporn Sae-lim, Karsidete Teeranitayatarn, Thaweesak Songserm, Rungrueang Yodsheewan, Dachrit Nilubol, Dachrit Nilubol, Wanpen Chaicumpa, Nitat Sookrung, Nitat Sookrung   +13 more
openaire   +3 more sources

Development of an indirect ELISA to detect PEDV specific IgA antibody based on a PEDV epidemic strain

BMC Veterinary Research, 2022
Abstract Background Porcine epidemic diarrhea (PED), a swine epidemic disease caused by porcine epidemic diarrhea virus (PEDV), is characterized by severe watery diarrhea, vomiting, dehydration and high mortality in piglets, and has caused serious economic losses to the global porcine industry.
Kun Wang, Zhiqiang Hu, Mingyu Fan, Zhenwen Shao, Qiannan Yu, Xiaowen Li   +5 more
openaire   +3 more sources

Recombinant Chimeric Transmissible Gastroenteritis Virus (TGEV)—Porcine Epidemic Diarrhea Virus (PEDV) Virus Provides Protection against Virulent PEDV [PDF]

Viruses, 2019
Porcine epidemic diarrhea virus (PEDV) is an enteric coronavirus causing high morbidity and mortality in porcine herds worldwide. Although both inactivated and live attenuated vaccines have been extensively used, the emergence of highly virulent strains and the recurrent outbreaks even in vaccinated farms highlight the need of effective vaccines ...
Alejandro Pascual-Iglesias, Carlos M. Sanchez, Zoltan Penzes, Isabel Sola, Luis Enjuanes, Sonia Zuñiga   +5 more
openaire   +4 more sources

A flagellin-adjuvanted inactivated porcine epidemic diarrhea virus (PEDV) vaccine provides enhanced immune protection against PEDV challenge in piglets [PDF]

Archives of Virology, 2020
Since late 2010, outbreaks of porcine epidemic diarrhea (PED) have been reported in the swine industry in China. A variant PEDV strain that differs from strain CV777 causes prevalent PEDV infections which commercial vaccines based on CV777 cannot provide complete protection.
Xu, Xiangwei, Du, Luping, Fan, Baochao, Sun, Bing, Zhou, Jinzhu, Guo, Rongli, Yu, Zhengyu, Shi, Danyi, He, Kongwang, Li, Bin   +9 more
openaire   +2 more sources