Results 1 to 10 of about 571 (86)

Differences in cytokines expression between Vero cells and IPEC-J2 cells infected with porcine epidemic diarrhea virus

Frontiers in Microbiology, 2022
Porcine epidemic diarrhea virus (PEDV) primarily infects suckling piglets and causes severe economic losses to the swine industry. Cytokines, as part of the innate immune response, are important in PEDV infection. The cytokines secreted by cell infection
Chen Yuan, Lidan Sun, Ligong Chen, Limin Li, Zuojun Yao, Yawen Wang, Haiyong Guo, Tanqing Li, Qinye Song   +8 more
doaj   +3 more sources

Astaxanthin Alleviates Aflatoxin B1-Induced Oxidative Stress and Apoptosis in IPEC-J2 Cells via the Nrf2 Signaling Pathway

Toxins, 2023
Aflatoxin B1 (AFB1), a typical fungal toxin found in feed, is highly carcinogenic. Oxidative stress is one of the main ways it exerts its toxicity; therefore, finding a suitable antioxidant is the key to reducing its toxicity.
Yue Tian, Haoyu Che, Jinsheng Yang, Yongcheng Jin, Hao Yu, Chuanqi Wang, Yurong Fu, Na Li, Jing Zhang   +8 more
doaj   +3 more sources

Tannic Acid Induces the Mitochondrial Pathway of Apoptosis and S Phase Arrest in Porcine Intestinal IPEC-J2 Cells

Toxins, 2019
The presence of tannic acid (TA), which is widely distributed in plants, limits the utilization of non-grain feed. Illustrating the toxicity mechanism of TA in animals is important for preventing poisoning and for clinical development of TA.
Ji Wang, Haisi Xiao, Yuanyuan Zhu, Shuiping Liu, Zhihang Yuan, Jing Wu, Lixin Wen   +6 more
doaj   +3 more sources

Decreased S100A9 expression alleviates Clostridium perfringens beta2 toxin-induced inflammatory injury in IPEC-J2 cells [PDF]

PeerJ, 2023
Background S100 calcium-binding protein A9 (S100A9) is a commonly known pro-inflammatory factor involved in various inflammatory responses. Clostridium perfringens (C. perfringens ) type C is known to cause diarrhea in piglets.
Jie Li, Xiaoyu Huang, Kaihui Xie, Juanli Zhang, Jiaojiao Yang, Zunqiang Yan, Shuangbao Gun   +6 more
doaj   +2 more sources

Comparison of expression profiles between undifferentiated and differentiated porcine IPEC-J2 cells

Porcine Health Management, 2022
Background The intestinal porcine enterocyte cell line (IPEC-J2) is a well-established model to study porcine intestinal physiology. IPEC-J2 cells undergo spontaneous differentiation during culture while changes in expression patterns of differentiated ...
Guolin Pi, Wenxin Song, Zijuan Wu, Yali Li, Huansheng Yang   +4 more
doaj   +1 more source

Lycopene Maintains Mitochondrial Homeostasis to Counteract the Enterotoxicity of Deoxynivalenol

Antioxidants, 2023
The intestinal tract is a target organ for Deoxynivalenol (DON) absorption and toxicity. Mitochondrial homeostasis imbalance is the gut toxicity mechanism of DON. Lycopene (LYC) has intestinal protective effects and can maintain mitochondrial homeostasis
Zihui Cai, Fengjuan Chen, Youshuang Wang, Xuebing Wang, Xu Yang, Cong Zhang   +5 more
doaj   +1 more source

The function of antimicrobial peptide MPX on the apoptosis and barrier of IPEC-J2 cells

Науковий вісник Львівського національного університету ветеринарної медицини та біотехнологій імені С.З. Ґжицького: Серія Ветеринарні науки, 2021
The porcine intestinal epithelial cell line IPEC-J2 cells, which were isolated from neonatal piglet mid-jejunum, the main components of the intestinal epithelium and play an important role in the intestine.
Xueqin Zhao
doaj   +1 more source

Comparing Two Intestinal Porcine Epithelial Cell Lines (IPECs): Morphological Differentiation, Function and Metabolism. [PDF]

PLoS ONE, 2015
The pig shows genetical and physiological resemblance to human, which predestines it as an experimental animal model especially for mucosal physiology. Therefore, the intestinal epithelial cell lines 1 and J2 (IPEC-1, IPEC-J2)--spontaneously immortalised
Constanze Nossol, Anicò Barta-Böszörményi, Stefan Kahlert, Werner Zuschratter, Heidi Faber-Zuschratter, Nicole Reinhardt, Siriluk Ponsuksili, Klaus Wimmers, Anne-Kathrin Diesing, Hermann-Josef Rothkötter   +9 more
doaj   +1 more source

11S Glycinin Up-Regulated NLRP-3-Induced Pyroptosis by Triggering Reactive Oxygen Species in Porcine Intestinal Epithelial Cells

Frontiers in Veterinary Science, 2022
11S glycinin is a major soybean antigenic protein, which induces human and animal allergies. It has been reported to induce intestinal porcine epithelial (IPEC-J2) cell apoptosis, but the role of pyroptosis in 11S glycinin allergies remains unknown.
Lei Wang, Zhifeng Sun, Weina Xie, Chenglu Peng, Hongyan Ding, Yu Li, Shibin Feng, Xichun Wang, Chang Zhao, Jinjie Wu   +9 more
doaj   +1 more source

The tissue expression level of BPI gene in piglets from newborn to weaning and its relationship with Gram-negative bacterial infection

Journal of Integrative Agriculture, 2020
The bactericidal/permeability increasing protein (BPI) has an important function of nonspecific killing of Gram-negative bacteria. In this study, qPCR was used to detect the expression of the BPI gene in twelve tissues of Meishan piglets from birth to ...
Chao-hui DAI, Yue CAO, Zhong-cheng GAO, Guo-qiang ZHU, Sheng-long WU, Wen-bin BAO   +5 more
doaj   +1 more source