Results 1 to 10 of about 5,753 (209)

Astaxanthin Alleviates Aflatoxin B1-Induced Oxidative Stress and Apoptosis in IPEC-J2 Cells via the Nrf2 Signaling Pathway [PDF]

Toxins, 2023
Aflatoxin B1 (AFB1), a typical fungal toxin found in feed, is highly carcinogenic. Oxidative stress is one of the main ways it exerts its toxicity; therefore, finding a suitable antioxidant is the key to reducing its toxicity.
Yue Tian, Haoyu Che, Jinsheng Yang, Yongcheng Jin, Hao Yu, Chuanqi Wang, Yurong Fu, Na Li, Jing Zhang   +8 more
doaj   +4 more sources

The Inflammatory Response to Enterotoxigenic E. coli and Probiotic E. faecium in a Coculture Model of Porcine Intestinal Epithelial and Dendritic Cells [PDF]

Mediators of Inflammation, 2018
The gut epithelium constitutes an interface between the intestinal contents and the underlying gut-associated lymphoid tissue (GALT) including dendritic cells (DC).
Henriette Loss, Jörg R. Aschenbach, Karsten Tedin, Friederike Ebner, Ulrike Lodemann   +4 more
doaj   +2 more sources

The function of antimicrobial peptide MPX on the apoptosis and barrier of IPEC-J2 cells [PDF]

Науковий вісник Львівського національного університету ветеринарної медицини та біотехнологій імені С.З. Ґжицького: Серія Ветеринарні науки, 2021
The porcine intestinal epithelial cell line IPEC-J2 cells, which were isolated from neonatal piglet mid-jejunum, the main components of the intestinal epithelium and play an important role in the intestine.
Xueqin Zhao
doaj   +3 more sources

Differences in cytokines expression between Vero cells and IPEC-J2 cells infected with porcine epidemic diarrhea virus [PDF]

Frontiers in Microbiology, 2022
Porcine epidemic diarrhea virus (PEDV) primarily infects suckling piglets and causes severe economic losses to the swine industry. Cytokines, as part of the innate immune response, are important in PEDV infection. The cytokines secreted by cell infection
Chen Yuan, Lidan Sun, Ligong Chen, Limin Li, Zuojun Yao, Yawen Wang, Haiyong Guo, Tanqing Li, Qinye Song   +8 more
doaj   +2 more sources

Decreased S100A9 expression alleviates Clostridium perfringens beta2 toxin-induced inflammatory injury in IPEC-J2 cells [PDF]

PeerJ, 2023
Background S100 calcium-binding protein A9 (S100A9) is a commonly known pro-inflammatory factor involved in various inflammatory responses. Clostridium perfringens (C. perfringens ) type C is known to cause diarrhea in piglets.
Jie Li, Xiaoyu Huang, Kaihui Xie, Juanli Zhang, Jiaojiao Yang, Zunqiang Yan, Shuangbao Gun   +6 more
doaj   +3 more sources

Inhibition of Enterotoxigenic Escherichia coli adhesion via aptamers prevents infection in IPEC-J2 cells [PDF]

BMC Microbiology
Enterotoxigenic Escherichia coli (ETEC) is a well-known strain associated with post-weaning diarrhea. Consequently, strategies to prevent and inhibit ETEC infections are critically important. Aptamers are single-stranded DNA or RNA sequences that exhibit
Zefeng Wang, Tao Xu, Jianxi Tan, Yan Zhou, Qiyi Li, Zhihui Peng   +5 more
doaj   +2 more sources

Protective effects of Curcumin-Zinc complex on inflammatory damage of IPEC-J2 cells induced by bacterial lipopolysaccharide [PDF]

AMB Express
The present study aimed to investigate the potential mitigative effects of the Curcumin-Zinc Complex (Cur-Zn) on bacterial lipopolysaccharide (LPS)-induced inflammatory damage in porcine small intestinal epithelial cells (IPEC-J2).
Xiaopeng Tang, Yan Zeng, Meijun Li
doaj   +2 more sources

Luteolin attenuates LPS-induced damage in IPEC-J2 cells by enhancing mitophagy via AMPK signaling pathway activation [PDF]

Frontiers in Nutrition
BackgroundLuteolin (LUT), a flavonoid compound widely present in natural plants, has been extensively studied for its diverse biological properties, involving anti-inflammatory,antioxidant, anti-apoptosis and other properties.MethodsThe aim of this study
Jianyun Yuan, Ke Zhang, Lingling Yang, Xinyi Cheng, Jinyan Chen, Xiaoquan Guo, Huabin Cao, Caiying Zhang, Chenghong Xing, Guoliang Hu, Yu Zhuang   +10 more
doaj   +2 more sources

Naringenin Inhibits Enterotoxigenic Escherichia coli-Induced Ferroptosis via Targeting HSP90 in IPEC-J2 Cells [PDF]

Antioxidants
Enterotoxigenic Escherichia coli (ETEC) leads to severe diarrhea in piglets. Naringenin (Nar), a natural flavonoid compound, is known for its antibacterial and anti-antioxidant properties.
Pengxin Jiang, Kangping Liu, Yanan Cui, Puyu Liu, Xutao Wang, Zijuan Hou, Jiamei Cui, Ning Chen, Jinghui Fan, Jianguo Li, Yuzhu Zuo, Yan Li   +11 more
doaj   +2 more sources

Genistein Alleviates Intestinal Oxidative Stress by Activating the Nrf2 Signaling Pathway in IPEC-J2 Cells [PDF]

Veterinary Sciences
In the weaning period, piglets often face oxidative stress, which will cause increased diarrhea and mortality. Genistein, a flavonoid, which is extracted from leguminous plants, possesses anti-inflammatory and antioxidative bioactivities. However, little
Yanpin Li, Long Cai, Qingyue Bi, Wenjuan Sun, Yu Pi, Xianren Jiang, Xilong Li   +6 more
doaj   +2 more sources