Results 41 to 50 of about 4,777,996 (166)

Persistence Infection of TGEV Promotes Enterococcus faecalis Infection on IPEC-J2 Cells

International Journal of Molecular Sciences, 2022
Transmissible gastroenteritis virus (TGEV) is a coronavirus causing diarrhea with high incidence in swine herds. Its persistent infection might lead to epithelial-mesenchymal transition (EMT) of swine intestinal epithelial cells, followed by subsequent infections of other pathogens. Enterococcus faecalis (E.
Zhenzhen Guo, Chenxin Zhang, Jiajun Dong, Yabin Wang, Hui Hu, Liying Chen   +5 more
openaire   +2 more sources

Overexpression of POLDIP3 inhibits PDCoV replication in IPEC-J2 cells.

, 2023
(A) IPEC-J2 cells were transduced with a bicistronic lentivirus vector expressing ZsGreen alone (vector control) or POLDIP3 plus ZsGreen as described in Materials and Methods. (B) Overexpression of POLDIP3 in IPEC-J2 cells.
Jianfei Chen (3186999), Jin Tian (158712), Haoxin Yan (17108715), Mingwei Li (1914862), Longjun Guo (315268), Yudi Pan (7309513), Hongyan Shi (1988656), Da Shi (1455439), Li Feng (77923), Yang Wu (66682)   +9 more
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Integrins Were Involved in Soybean Agglutinin Induced Cell Apoptosis in IPEC-J2 [PDF]

International Journal of Molecular Sciences, 2018
Abstract: Soybean agglutinin (SBA), is a non-fiber carbohydrate related protein and a major anti-nutritional factor. Integrins, transmembrane glycoproteins, are involved in many biological processes. Although recent work suggested that integrins are involved in SBA-induced cell-cycle alterations, no comprehensive study has reported whether integrins ...
Li Pan, Yuan Zhao, Mohammed Hamdy Farouk, Nan Bao, Tao Wang, Guixin Qin   +5 more
openaire   +2 more sources

Entry of sapelovirus into IPEC-J2 cells is dependent on caveolae-mediated endocytosis

Virology Journal, 2019
Porcine sapelovirus (PSV), a species of the genus Sapelovirus within the family Picornaviridae, are a significant cause of enteritis, pneumonia, polioencephalomyelitis and reproductive disorders in pigs. However, the life cycle of PSV on the molecular level is largely unknown.Here, we used chemical inhibitors, RNA interference, and overexpression of ...
Tingting Zhao, Li Cui, Xiangqian Yu, Zhonghai Zhang, Xiaojuan Shen, Xiuguo Hua   +5 more
openaire   +3 more sources

Over-expression of miR-146b and its regulatory role in intestinal epithelial cell viability, proliferation, and apoptosis in piglets

Biology Direct, 2017
Background Weaning stress affects the small intestine of piglets. MiR-146b is differentially expressed in suckling and weaned piglets. In this study, we evaluated the effects of miR-146b on cell viability, proliferation, and apoptosis in IPEC-J2 cells ...
Xin Tao, Shujie Liu, Xiaoming Men, Ziwei Xu   +3 more
doaj   +1 more source

METTL3 Regulates the Inflammatory Response in CPB2 Toxin-Exposed IPEC-J2 Cells through the TLR2/NF-κB Signaling Pathway

, 2022
Clostridium perfringens beta2 (CPB2) toxin is one of the main pathogenic toxins produced by Clostridium perfringens, which causes intestinal diseases in animals and humans.
Shuangbao Gun, Wang, Wei, Xiaoyu Huang, Jiaojiao Yang, Juanli Zhang, Xiaoli Gao, Ruirui Luo, Zhang, Juanli, Zunqiang Yan, Yang, Qiaoli, Luo, Ruirui, Zhang, Bo, Wei Wang, Gun, Shuangbao, Wang, Pengfei, Kaihui Xie, Xie, Kaihui, Jie Li, Gao, Xiaoli, Yang, Jiaojiao, Li, Jie, Bo Zhang, Huang, Xiaoyu, Qiaoli Yang, Yan, Zunqiang, Pengfei Wang   +25 more
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Transcriptomics analysis of IPEC-J2 cells infected by PEDV.

, 2023
(A) A volcano plot of RNA-sequencing data from IPEC-J2 cells infected with PEDV infection (MOI = 1) at 20 hpi. (B) A heatmap with the abundance of mitochondria-related genes based on RNA-sequencing data.
Bin Li (39349), Jiahuang Lv (14808916), Qiru Zeng (14808922), Jizong Li (5039048), Siyuan Ding (506428), Rongli Guo (310263), Jinzhu Zhou (14330535), Chunyan Zhong (3162063), Qingtao Liu (305819), Wei Wang (17594), Xuejiao Zhu (177257), Avan Antia (14808919), Baochao Fan (798837), Mingjun Zhu (5817179)   +13 more
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Glucose significantly enhances enterotoxigenic Escherichia coli adherence to intestinal epithelial cells through its effects on heat-labile enterotoxin production. [PDF]

PLoS ONE, 2014
The present study tested whether exposure of enterotoxigenic Escherichia coli (ETEC) to glucose at different concentrations in the media results in increased bacterial adherence to host cells through increased heat-labile enterotoxin (LT) production ...
Prageeth Wijemanne, Rodney A Moxley
doaj   +1 more source

Leucine modulates the IPEC-J2 cell proteome associated with cell proliferation, metabolism and phagocytosis

Animal Nutrition, 2018
Leucine can affect intestinal protein expressions, and improve mucosal immune function. However, little study has been conducted to determine the change of protein component by leucine treatment in intestine epithelial cells. The present study was to cover the key proteins and cell pathways that could be regulated by leucine treatment in porcine ...
Xiangbing Mao, Man Ren, Daiwen Chen, Bing Yu, Lianqiang Che, Jun He, Junqiu Luo, Yuheng Luo, Jianping Wang, Hui Sun   +9 more
openaire   +3 more sources

Comprehensive Analysis Revealed the Potential Roles of N6-Methyladenosine (m6A) Mediating E. coli F18 Susceptibility in IPEC-J2 Cells

, 2022
Post-weaning diarrhea caused by enterotoxigenic Escherichia coli F18 (E. coli F18) causes significant economic losses for pig producers. N6-methyladenosine (m6A) is a highly abundant epitranscriptomic marker that has been found to be involved in ...
Li, Tong, Bao, Wenbin, Jin, Jian, Yang, Li, Yifu Wang, Jian Jin, Zhengchang Wu, Wenbin Bao, Wu, Shenglong, Li Yang, Shenglong Wu, Tong Li, Wu, Zhengchang, Wang, Yifu   +13 more
core   +1 more source