Results 1 to 10 of about 2,794,554 (162)

Interpretable machine learning identifies a clinically inferred inflammasome-associated inflammatory injury phenotype in children with adenovirus pneumonia [PDF]

Frontiers in Cellular and Infection Microbiology
BackgroundSevere adenovirus pneumonia in children is characterized by persistent fever, systemic inflammation, and extrapulmonary tissue injury. Although adenovirus can activate inflammasome pathways, direct inflammasome biomarkers are not routinely ...
Jie Li, Yabin Wu, Yang Huang, Wenhua Deng   +3 more
doaj   +2 more sources

inlF Enhances Listeria monocytogenes Early-Stage Infection by Inhibiting the Inflammatory Response

Frontiers in Cellular and Infection Microbiology, 2022
The internalin family proteins, which carry the leucine repeat region structural motif, play diverse roles in Listeria monocytogenes (Lm) infection and pathogenesis.
Zhiting Ling, Zhiting Ling, Zhiting Ling, Zhiting Ling, Dan Zhao, Dan Zhao, Dan Zhao, Dan Zhao, Xinyu Xie, Xinyu Xie, Xinyu Xie, Xinyu Xie, Hao Yao, Hao Yao, Hao Yao, Hao Yao, Yuting Wang, Yuting Wang, Yuting Wang, Yuting Wang, Suwei Kong, Suwei Kong, Suwei Kong, Suwei Kong, Xiang Chen, Xiang Chen, Xiang Chen, Xiang Chen, Zhiming Pan, Zhiming Pan, Zhiming Pan, Zhiming Pan, Xin’an Jiao, Xin’an Jiao, Xin’an Jiao, Xin’an Jiao, Yuelan Yin, Yuelan Yin, Yuelan Yin, Yuelan Yin   +39 more
doaj   +1 more source

Low-Molecular-Weight Chitosan Attenuates Lipopolysaccharide-Induced Inflammation in IPEC-J2 Cells by Inhibiting the Nuclear Factor-κB Signalling Pathway

Molecules, 2021
Low-molecular-weight chitosan (LMWC), a product of chitosan deacetylation, possesses anti-inflammatory effects. In the present study, a porcine small intestinal epithelial cell line, IPEC-J2, was used to assess the protective effects of LMWC on ...
Jiao Zhang, Jin Wan, Daiwen Chen, Bing Yu, Jun He   +4 more
doaj   +1 more source

MSC-ACE2 Ameliorates Streptococcus uberis-Induced Inflammatory Injury in Mammary Epithelial Cells by Upregulating the IL-10/STAT3/SOCS3 Pathway

Frontiers in Immunology, 2022
In the dairy industry, Streptococcus uberis (S. uberis) is one of the most important pathogenic bacteria associated with mastitis in milk-producing cows, causing vast economic loss.
Shuping Yan, Chonghao Zhang, Xiaoxia Ji, Gang Wu, Xinhe Huang, Yafeng Zhang, Yuanshu Zhang   +6 more
doaj   +1 more source

Research progress on influence of PM2.5 on allergic rhinitis

环境与职业医学, 2023
Allergic rhinitis (AR) is one of the main chronic inflammatory diseases that pose a global threat. Its symptoms persist for a long time, recur, and seriously affect the physical and mental health of the patients.
Ying ZHANG, Ling HE, Huai WEI, Weidong WU, Juan LI   +4 more
doaj   +1 more source

Recent Advances in the Role of Nuclear Factor Erythroid-2-Related Factor 2 in Spinal Cord Injury: Regulatory Mechanisms and Therapeutic Options

Frontiers in Aging Neuroscience, 2022
Nuclear factor erythroid-2-related factor 2 (Nrf2) is a pleiotropic transcription factor, and it has been documented that it can induce defense mechanisms both oxidative stress and inflammatory injury.
Tianqi Jiang, Tianqi Jiang, Yongxiong He
doaj   +1 more source

Scutellaria baicalensis georgi is a promising candidate for the treatment of autoimmune diseases

Frontiers in Pharmacology, 2022
Autoimmune diseases a group of disorders elicited by unexpected outcome of lymphocytes self-tolerance failure, and the common members of which include multiple sclerosis, systemic lupus erythematosus, inflammatory bowel disease, rheumatoid arthritis, and
Jun Wang, Shanshan Chen, Jizhou Zhang, Jiasi Wu   +3 more
doaj   +1 more source

lnc001776 Affects CPB2 Toxin-Induced Excessive Injury of Porcine Intestinal Epithelial Cells via Activating JNK/NF-kB Pathway through ssc-let-7i-5p/IL-6 Axis

Cells, 2023
Piglet diarrhea caused by Clostridium perfringens (C. perfringens) type C (CpC) seriously endangers the development of the pig production industry. C. perfringens beta2 (CPB2) toxin is a virulent toxin produced by CpC.
Kaihui Xie, Zunqiang Yan, Qiaoli Yang, Xiaoyu Huang, Pengfei Wang, Xiaoli Gao, Jie Li, Shuangbao Gun   +7 more
doaj   +1 more source

Mmu_circ_0000037 inhibits the progression of acute pancreatitis by miR‐92a‐3p/Pias1 axis

Immunity, Inflammation and Disease, 2023
Background Acute pancreatitis (AP) is an inflammatory disease with high mortality. Previous study has suggested that circular RNAs are dysregulated and involved in the regulation of inflammatory responses in AP.
Hua Chen, Jun Tu, Lei He, Ning Gao, Weiqiang Yang   +4 more
doaj   +1 more source

Oral administration of Lactobacillus brevis 23017 combined with ellagic acid attenuates intestinal inflammatory injury caused by Eimeria infection by activating the Nrf2/HO-1 antioxidant pathway

Veterinary Research, 2022
The aim of this study was to investigate whether oral administration of Lactobacillus brevis 23017 (LB) alone and in combination with ellagic acid inhibits ChTLR15/ChNLRP3/ChIL-1β by activating the Nrf2/HO-1 pathway to attenuate intestinal inflammatory ...
Xuelian Yang, Xinghui Pan, Zhipeng Jia, Bingrong Bai, Wenjing Zhi, Hang Chen, Chunli Ma, Dexing Ma   +7 more
doaj   +1 more source