Results 11 to 20 of about 2,794,554 (162)

Endothelial Cdc42 deficiency impairs endothelial regeneration and vascular repair after inflammatory vascular injury

Respiratory Research, 2018
Background Endothelial cell (EC) regeneration is essential for inflammation resolution and vascular integrity recovery after inflammatory vascular injury. Cdc42 is a central regulator of cell survival and vessel formation in EC development.
Jiawen Lv, Junchao Zeng, Fukun Guo, Yiran Li, Mengying Xu, Yuanxiong Cheng, Lin Zhang, Shaoxi Cai, Yinghua Chen, Yi Zheng, Guodong Hu   +10 more
doaj   +2 more sources

The effects of parenteral or dietary omega-3 polyunsaturated fatty acids in rat models of spinal cord injury [PDF]

, 2010
PhDThere is currently no effective treatment for spinal cord injury (SCI). Long chain omega-3 polyunsaturated fatty acids (PUFA) such as docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) have beneficial effects in various neurological disorders.
Hall, Jodie Christine Elizabeth
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Characteristics of inflammatory response and repair after experimental blast lung injury in rats [PDF]

, 2023
BACKGROUND AND OBJECTIVES Blast-induced lung injury is associated with inflammatory, which are characterised by disruption of the alveolar-capillary barrier, haemorrhage, pulmonary infiltrateration causing oedema formation, pro-inflammatory cytokine ...
Uz Stammberger, Yalda Hadizamani, Hamacher, Jürg, Bally, Lia, Hanno Huwer, Albrecht Wendel, Hadizamani, Yalda, Lucas, Rudolf, Ueli Moehrlen, Lia Bally, Rudolf Lucas, Moehrlen, Ueli, Stammberger, Uz, Huwer, Hanno, Wendel, Albrecht, Jürg Hamacher, Lucas, Rudolf; https://orcid.org/, Hadizamani, Yalda; https://orcid.org/, Moehrlen, Ueli; https://orcid.org/, Bally, Lia; https://orcid.org/   +19 more
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Effect of deoxynivalenol on inflammatory injury on the glandular stomach in chick embryos

Poultry Science, 2023
: Deoxynivalenol (DON) has a strong toxic effect on the gastrointestinal mucosa of poultry. In this study, we evaluated chicken embryo development and glandular stomach damage to clarify the immunotoxic effects of DON injected through the allantoic ...
Lele Hou, Hao Yuan, Yang Liu, Xinyuan Sun, Jiagao Chang, Hao Zhang, Junchao Zhang, Jieyu Sun, Qiang Wang, Fu Chen   +9 more
doaj   +1 more source

lncRNA myocardial infarction-associated transcript (MIAT) knockdown alleviates LPS-induced chondrocytes inflammatory injury via regulating miR-488-3p/sex determining region Y-related HMG-box 11 (SOX11) axis

Open Life Sciences, 2021
Long noncoding RNA (lncRNA) has been shown to be involved in the development of osteoarthritis (OA), an age-related bone and joint disease. However, the function and possible molecular mechanism of lncRNA myocardial infarction-associated transcript (MIAT)
Pan Weiwei, Wang Haibao, Ruan Jianwei, Zheng Wenbiao, Chen Fanghu, Kong Jinsong, Wang Yong   +6 more
doaj   +1 more source

The uncoordinated-5 homolog B receptor affects hepatic ischemia reperfusion injury [PDF]

, 2012
Recent evidence has demonstrated additional roles for the neuronal guidance protein receptor UNC5B outside the nervous system. Given the fact that ischemia reperfusion injury (IRI) of the liver is a common source of liver dysfunction and the role of ...
Tiago Granja (147967), Tiago Granja, David Köhler (147965), Rosenberger, Peter, Klemens König, Carla Jennewein (147970), König, Klemens, Valbona Mirakaj, Mirakaj, Valbona, Tran, Thi Hoai Nguyen, Granja, Tiago, Nguyen Tran, Valbona Mirakaj (147976), Kröhnert, Friedemann, Peter Rosenberger, Nguyen Tran (147973), Klemens König (147961), Jennewein, Carla, Tran, Nguyen, Peter Rosenberger (37609), Carla Jennewein, Köhler, David, David Köhler, Friedemann Kröhnert, Friedemann Kröhnert (147979), Jennewein Carla, König Klemens, Köhler David, Granja Tiago, Rosenberger Peter, Tran Nguyen, Mirakaj Valbona, Granja, Tiago Folgosa, Kröhnert Friedemann   +33 more
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Klotho inhibits the activation of NLRP3 inflammasome to alleviate lipopolysaccharide-induced inflammatory injury in A549 cells and restore mitochondrial function through SIRT1/Nrf2 signaling pathway

Chinese Journal of Physiology, 2023
Acute lung injury is a severe clinical condition constituting a major cause of mortality in intensive care units. This study aimed to investigate the role of klotho in alleviating lipopolysaccharide (LPS)-induced acute lung injury. LPS-induced acute lung
Yanjun Zeng, Gang Xu, Congrui Feng, Danyan Cai, Sizhi Wu, Yuanling Liu, Yuluo Chen, Wei Ma   +7 more
doaj   +1 more source

Phosphorylation of Vasodilator-Stimulated Phosphoprotein (VASP) dampens hepatic ischemia-reperfusion injury [PDF]

, 2011
Recent work has demonstrated that the formation of platelet neutrophil complexes (PNCs) affects inflammatory tissue injury. Vasodilator-stimulated phosphoprotein (VASP) is crucially involved into the control of PNC formation and myocardial reperfusion ...
Birk, Philipp, Morote-Garcia, Julio C., Rosenberger, Peter, Peter Rosenberger, Eldh, Therese, Andreas Straub, Klemens König, Philipp Birk, Therese Eldh, König, Klemens, Julio C Morote-Garcia, Straub, Andreas, Köhler, David, David Köhler, Eldh Therese, König Klemens, Straub Andreas, Morote-Garcia Julio C., Köhler David, Birk Philipp, Rosenberger Peter   +20 more
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The neuronal guidance protein netrin-1 reduces alveolar inflammation in a porcine model of acute lung injury [PDF]

, 2010
Introduction: Acute lung injury (ALI) is an inflammatory disorder of pulmonary or extrapulmonary origin. We have previously demonstrated that netrin-1 dampens murine ALI, and in an attempt to advance this finding into future clinical practice we ...
Kristina Waibler, Gabriele Nöldge-Schomburg, Rosenberger, Peter, Dierk A Vagts, Peter Rosenberger, Vagts, Dierk A., Klemens König, Thomas Iber, Christian Mutz, Westermann, Phillipp, Nöldge-Schomburg, Gabriele, Mutz, Christian, König, Klemens, Iber, Thomas, Valbona Mirakaj, Mirakaj, Valbona, Phillipp Westermann, Waibler, Kristina   +17 more
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Long-term persistance of the pathophysiologic response to severe burn injury. [PDF]

, 2011
Main contributors to adverse outcomes in severely burned pediatric patients are profound and complex metabolic changes in response to the initial injury. It is currently unknown how long these conditions persist beyond the acute phase post-injury.
Kraft, Robert, Marc G Jeschke, David N Herndon, Felicia N Williams, Gabriela A Kulp, Ronald P. Mlcak, Oscar E. Suman, Felicia N. Williams, Jeschke Marc G., Kulp, Gabriela A., Celeste C. Finnerty, Suman, Oscar E., Gerd G. Gauglitz, Kulp Gabriela A., Marc G. Jeschke, Finnerty Celeste C., Gabriela A. Kulp, Gerd G Gauglitz, Mlcak, Ronald P., David N. Herndon, Gauglitz, Gerd G., Herndon, David N., Jeschke, Marc G., Herndon David N., Finnerty, Celeste C., Mlcak Ronald P., Ronald P Mlcak, Suman Oscar E., Williams, Felicia N., Kraft Robert, Williams Felicia N., Gauglitz Gerd G., Oscar E Suman, Celeste C Finnerty, Robert Kraft   +34 more
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