Results 1 to 10 of about 22,373 (186)

IPEC-J2 as a cellular model for studying intestinal mucus [PDF]

Scientific Reports
Mucus in the proximal small intestine serves critical protective and transport functions, regulating nutrient absorption to enterocytes. The porcine jejunal epithelial cell line IPEC-J2 is widely used to study epithelial barrier function, yet its ...
Frédéric Dessauge, Annie Vincent, Christine Trefeu, Frédérique Mayeur-Nickel, Sandra Wiart-Letort, Adam Macierzanka, Martin Beaumont, Myriam M.-L. Grundy   +7 more
doaj   +5 more sources

Silver and Copper Nanoparticles Hosted by Carboxymethyl Cellulose Reduce the Infective Effects of Enterotoxigenic Escherichia coli:F4 on Porcine Intestinal Enterocyte IPEC-J2 [PDF]

Microorganisms
Zero-valent copper and silver metals (Ms) nanoparticles (NPs) supported on carboxymethylcellulose (CMC) were synthesized for treating Enterotoxigenic Escherichia coli fimbriae 4 (ETEC:F4), a major cause of diarrhea in post-weaned pigs.
Armelle Tchoumi Neree, Farzaneh Noori, Abdelkrim Azzouz, Marcio Costa, John Morris Fairbrother, Mircea Alexandru Mateescu, Younes Chorfi   +6 more
doaj   +3 more sources

Genistein Alleviates Intestinal Oxidative Stress by Activating the Nrf2 Signaling Pathway in IPEC-J2 Cells [PDF]

Veterinary Sciences
In the weaning period, piglets often face oxidative stress, which will cause increased diarrhea and mortality. Genistein, a flavonoid, which is extracted from leguminous plants, possesses anti-inflammatory and antioxidative bioactivities. However, little
Yanpin Li, Long Cai, Qingyue Bi, Wenjuan Sun, Yu Pi, Xianren Jiang, Xilong Li   +6 more
doaj   +3 more sources

Inhibition of Enterotoxigenic Escherichia coli adhesion via aptamers prevents infection in IPEC-J2 cells [PDF]

BMC Microbiology
Enterotoxigenic Escherichia coli (ETEC) is a well-known strain associated with post-weaning diarrhea. Consequently, strategies to prevent and inhibit ETEC infections are critically important. Aptamers are single-stranded DNA or RNA sequences that exhibit
Zefeng Wang, Tao Xu, Jianxi Tan, Yan Zhou, Qiyi Li, Zhihui Peng   +5 more
doaj   +2 more sources

Protective effects of Curcumin-Zinc complex on inflammatory damage of IPEC-J2 cells induced by bacterial lipopolysaccharide [PDF]

AMB Express
The present study aimed to investigate the potential mitigative effects of the Curcumin-Zinc Complex (Cur-Zn) on bacterial lipopolysaccharide (LPS)-induced inflammatory damage in porcine small intestinal epithelial cells (IPEC-J2).
Xiaopeng Tang, Yan Zeng, Meijun Li
doaj   +2 more sources

Luteolin attenuates LPS-induced damage in IPEC-J2 cells by enhancing mitophagy via AMPK signaling pathway activation [PDF]

Frontiers in Nutrition
BackgroundLuteolin (LUT), a flavonoid compound widely present in natural plants, has been extensively studied for its diverse biological properties, involving anti-inflammatory,antioxidant, anti-apoptosis and other properties.MethodsThe aim of this study
Jianyun Yuan, Ke Zhang, Lingling Yang, Xinyi Cheng, Jinyan Chen, Xiaoquan Guo, Huabin Cao, Caiying Zhang, Chenghong Xing, Guoliang Hu, Yu Zhuang   +10 more
doaj   +2 more sources

Comparative evaluation of the modulatory role of 1,25-dihydroxy-vitamin D3 on endoplasmic reticulum stress-induced effects in 2D and 3D cultures of the intestinal porcine epithelial cell line IPEC-J2 [PDF]

Journal of Animal Science and Biotechnology
Background The use of conventional two-dimensional (2D) culture of the porcine intestinal epithelial cell (IEC) line IPEC-J2 in animal nutrition research has the disadvantage that IEC function is studied under unphysiological conditions, which limits the
Gaiping Wen, Klaus Eder, Robert Ringseis
doaj   +2 more sources

Astaxanthin Alleviates Aflatoxin B1-Induced Oxidative Stress and Apoptosis in IPEC-J2 Cells via the Nrf2 Signaling Pathway

Toxins, 2023
Aflatoxin B1 (AFB1), a typical fungal toxin found in feed, is highly carcinogenic. Oxidative stress is one of the main ways it exerts its toxicity; therefore, finding a suitable antioxidant is the key to reducing its toxicity.
Hao Yu, Yong-Cheng Jin, Yurong Fu
exaly   +3 more sources

Unraveling the pathogenic potential of the Pentatrichomonas hominis PHGD strain: impact on IPEC-J2 cell growth, adhesion, and gene expression [PDF]

Parasite
Pentatrichomonas hominis, a flagellated parasitic protozoan, predominantly infects the mammalian digestive tract, often causing symptoms such as abdominal pain and diarrhea. However, studies investigating its pathogenicity are limited, and the mechanisms
Zhu Yibin, Cai Haiming, Fang Siyun, Shen Hanqin, Yan Zhuanqiang, Wang Dingai, Qi Nanshan, Li Juan, Lv Minna, Lin Xuhui, Hu Junjing, Song Yongle, Chen Xiangjie, Yin Lijun, Zhang Jianfei, Liao Shenquan, Sun Mingfei   +16 more
doaj   +2 more sources

Tannic Acid Induces the Mitochondrial Pathway of Apoptosis and S Phase Arrest in Porcine Intestinal IPEC-J2 Cells

Toxins, 2019
The presence of tannic acid (TA), which is widely distributed in plants, limits the utilization of non-grain feed. Illustrating the toxicity mechanism of TA in animals is important for preventing poisoning and for clinical development of TA.
Chenglin Yang, Jing Wu, Lixin Wen
exaly   +3 more sources