Results 21 to 30 of about 5,777 (211)

<i>Parabacteroides goldsteinii</i> mitigates the lipopolysaccharide-induced inflammatory response in IPEC-J2 cells. [PDF]

Front Vet Sci
IntroductionThe misuse of antibiotics threatens animal health and food safety and limits the development of livestock and poultry farming. In animal husbandry, probiotics can be used as an alternative to antibiotics because of their environmental protection and high efficiency.
Zhang J, Li A, He Y, Guo T, Ge Y, Pan H, Dong C.   +6 more
europepmc   +4 more sources

Comparing Two Intestinal Porcine Epithelial Cell Lines (IPECs): Morphological Differentiation, Function and Metabolism. [PDF]

PLoS ONE, 2015
The pig shows genetical and physiological resemblance to human, which predestines it as an experimental animal model especially for mucosal physiology. Therefore, the intestinal epithelial cell lines 1 and J2 (IPEC-1, IPEC-J2)--spontaneously immortalised
Constanze Nossol, Anicò Barta-Böszörményi, Stefan Kahlert, Werner Zuschratter, Heidi Faber-Zuschratter, Nicole Reinhardt, Siriluk Ponsuksili, Klaus Wimmers, Anne-Kathrin Diesing, Hermann-Josef Rothkötter   +9 more
doaj   +1 more source

Lycopene Maintains Mitochondrial Homeostasis to Counteract the Enterotoxicity of Deoxynivalenol

Antioxidants, 2023
The intestinal tract is a target organ for Deoxynivalenol (DON) absorption and toxicity. Mitochondrial homeostasis imbalance is the gut toxicity mechanism of DON. Lycopene (LYC) has intestinal protective effects and can maintain mitochondrial homeostasis
Zihui Cai, Fengjuan Chen, Youshuang Wang, Xuebing Wang, Xu Yang, Cong Zhang   +5 more
doaj   +1 more source

Persistence Infection of TGEV Promotes Enterococcus faecalis Infection on IPEC-J2 Cells. [PDF]

Int J Mol Sci, 2022
Transmissible gastroenteritis virus (TGEV) is a coronavirus causing diarrhea with high incidence in swine herds. Its persistent infection might lead to epithelial-mesenchymal transition (EMT) of swine intestinal epithelial cells, followed by subsequent infections of other pathogens. Enterococcus faecalis (E.
Guo Z, Zhang C, Dong J, Wang Y, Hu H, Chen L.   +5 more
europepmc   +3 more sources

STIM1 promotes IPEC-J2 porcine epithelial cell restitution by TRPC1 signaling

Animal Biotechnology, 2021
Intestinal epithelial restitution is partly dependent on cell migration, which reseals superficial wounding after injury. Here, we tested the hypothesis that stromal interaction molecule 1(STIM1) regulates porcine intestinal epithelial cell migration by activating transient receptor potential canonical 1 (TRPC1) signaling.
Weiwei Mo, Guangmang Liu, Caimei Wu, Gang Jia, Hua Zhao, Xiaoling Chen, Jing Wang   +6 more
openaire   +2 more sources

Infection of Porcine Circovirus 2 (PCV2) in Intestinal Porcine Epithelial Cell Line (IPEC-J2) and Interaction between PCV2 and IPEC-J2 Microfilaments [PDF]

Virology Journal, 2014
Porcine circovirus-associated disease (PCVAD) is caused by a small pathogenic DNA virus, Porcine circovirus type 2 (PCV2), and is responsible for severe economic losses. PCV2-associated enteritis appears to be a distinct clinical manifestation of PCV2.
Yan, Mengfei, Zhu, Liqi, Yang, Qian
openaire   +2 more sources

11S Glycinin Up-Regulated NLRP-3-Induced Pyroptosis by Triggering Reactive Oxygen Species in Porcine Intestinal Epithelial Cells

Frontiers in Veterinary Science, 2022
11S glycinin is a major soybean antigenic protein, which induces human and animal allergies. It has been reported to induce intestinal porcine epithelial (IPEC-J2) cell apoptosis, but the role of pyroptosis in 11S glycinin allergies remains unknown.
Lei Wang, Zhifeng Sun, Weina Xie, Chenglu Peng, Hongyan Ding, Yu Li, Shibin Feng, Xichun Wang, Chang Zhao, Jinjie Wu   +9 more
doaj   +1 more source

Differences in cytokines expression between Vero cells and IPEC-J2 cells infected with porcine epidemic diarrhea virus

Frontiers in Microbiology, 2022
Porcine epidemic diarrhea virus (PEDV) primarily infects suckling piglets and causes severe economic losses to the swine industry. Cytokines, as part of the innate immune response, are important in PEDV infection. The cytokines secreted by cell infection
Chen Yuan, Lidan Sun, Ligong Chen, Limin Li, Zuojun Yao, Yawen Wang, Haiyong Guo, Tanqing Li, Qinye Song   +8 more
doaj   +1 more source

In vitro characterization of TMPRSS2 inhibition in IPEC-J2 cells [PDF]

Journal of Enzyme Inhibition and Medicinal Chemistry, 2016
The transmembrane serine protease, TMPRSS2 is an important target in the treatment of seasonal influenza infections and contributes to prostate carcinogenesis and metastasis. In this study, the effect of the synthetic TMPRSS2 inhibitor I-432 on jejunal IPEC-J2 cell monolayers cultured on membrane inserts was characterized. Using a fluorogenic substrate,
Pászti-Gere, Erzsébet, Czimmermann, Eszter, Ujhelyi, Gabriella, Balla, Péter, Maiwald, Alexander, Steinmetzer, Torsten   +5 more
openaire   +3 more sources

Growth behavior and mRNA expression profiling during growth of IPEC-J2 cells. [PDF]

BMC Res Notes
Abstract Objective The IPEC-J2 cell line is used as an in vitro small intestine model for swine, but it is also used as a model for the human intestine, presenting a relatively unique setting. By combining electric cell-substrate impedance sensing, with next-generation-sequencing technology, we showed that mRNA gene ...
Binder ARD, Mussack V, Kirchner B, Pfaffl MW.   +3 more
europepmc   +6 more sources