Results 21 to 30 of about 22,373 (186)

SLC4A11 and MFSD3 Gene Expression Changes in Deoxynivalenol Treated IPEC-J2 Cells [PDF]

Frontiers in Genetics, 2021
Deoxynivalenol (DON) caused serious cytotoxicity for animal cells. However, genes involved in regulating DON toxicity and the underlying molecular mechanisms remain largely unknown. This study explored the role of SLC4A11 and MFSD3 in alleviating DON toxicity and analyzed the DNA methylation changes of these two genes. Viability and cell cycle analysis
Yafei Xu, Xiaolei Chen, Luchen Yu, Yi Wang, Haifei Wang, Zhengchang Wu, Shenglong Wu, Shenglong Wu, Wenbin Bao, Wenbin Bao   +9 more
openaire   +3 more sources

Effects of daidzein on antioxidant capacity in weaned pigs and IPEC-J2 cells

Animal Nutrition, 2022
Our previous study found that soybean isoflavones in soybean meal play an important role in improving growth performance and antioxidant capacity in pigs. However, it is still unknown whether long-term supplementation with daidzein, an active molecule deglycosylated from daidzin, in a corn-soybean meal diet can enhance growth performance in pigs. Thus,
Yanpin Li, Xianren Jiang, Long Cai, Yanli Zhang, Hongbiao Ding, Jingdong Yin, Xilong Li   +6 more
openaire   +3 more sources

11S Glycinin Up-Regulated NLRP-3-Induced Pyroptosis by Triggering Reactive Oxygen Species in Porcine Intestinal Epithelial Cells

Frontiers in Veterinary Science, 2022
11S glycinin is a major soybean antigenic protein, which induces human and animal allergies. It has been reported to induce intestinal porcine epithelial (IPEC-J2) cell apoptosis, but the role of pyroptosis in 11S glycinin allergies remains unknown.
Lei Wang, Zhifeng Sun, Weina Xie, Chenglu Peng, Hongyan Ding, Yu Li, Shibin Feng, Xichun Wang, Chang Zhao, Jinjie Wu   +9 more
doaj   +1 more source

Differences in cytokines expression between Vero cells and IPEC-J2 cells infected with porcine epidemic diarrhea virus

Frontiers in Microbiology, 2022
Porcine epidemic diarrhea virus (PEDV) primarily infects suckling piglets and causes severe economic losses to the swine industry. Cytokines, as part of the innate immune response, are important in PEDV infection. The cytokines secreted by cell infection
Chen Yuan, Lidan Sun, Ligong Chen, Limin Li, Zuojun Yao, Yawen Wang, Haiyong Guo, Tanqing Li, Qinye Song   +8 more
doaj   +1 more source

Carvacrol Protects IPEC-J2 Cells from Oxidative Stress by Suppressing Autophagy. [PDF]

Int J Mol Sci
Oxidative stress impairs intestinal function and causes poor growth performance in piglets. Carvacrol is a natural essential oil, and its anti-oxidative and anti-inflammatory activities in the intestines of piglets have been reported in many studies.
Hsu MC, Wang HT, Chen CY.
europepmc   +3 more sources

In vitro characterization of TMPRSS2 inhibition in IPEC-J2 cells [PDF]

Journal of Enzyme Inhibition and Medicinal Chemistry, 2016
The transmembrane serine protease, TMPRSS2 is an important target in the treatment of seasonal influenza infections and contributes to prostate carcinogenesis and metastasis. In this study, the effect of the synthetic TMPRSS2 inhibitor I-432 on jejunal IPEC-J2 cell monolayers cultured on membrane inserts was characterized. Using a fluorogenic substrate,
Pászti-Gere, Erzsébet, Czimmermann, Eszter, Ujhelyi, Gabriella, Balla, Péter, Maiwald, Alexander, Steinmetzer, Torsten   +5 more
openaire   +3 more sources

Infection of Porcine Circovirus 2 (PCV2) in Intestinal Porcine Epithelial Cell Line (IPEC-J2) and Interaction between PCV2 and IPEC-J2 Microfilaments [PDF]

Virology Journal, 2014
Porcine circovirus-associated disease (PCVAD) is caused by a small pathogenic DNA virus, Porcine circovirus type 2 (PCV2), and is responsible for severe economic losses. PCV2-associated enteritis appears to be a distinct clinical manifestation of PCV2.
Yan, Mengfei, Zhu, Liqi, Yang, Qian
openaire   +2 more sources

A Medium-Throughput System for In Vitro Oxidative Stress Assessment in IPEC-J2 Cells [PDF]

International Journal of Molecular Sciences, 2020
The feed industry continuously seeks new molecules with antioxidant capacity since oxidative stress plays a key role in intestinal health. To improve screening of new antioxidants, this study aims to set up an assay to assess oxidative stress in the porcine small intestinal epithelial cell line IPEC-J2 using plate-reader-based analysis of fluorescence.
Miriam Ayuso, Steven Van Cruchten, Chris Van Ginneken   +2 more
openaire   +3 more sources

The tissue expression level of BPI gene in piglets from newborn to weaning and its relationship with Gram-negative bacterial infection

Journal of Integrative Agriculture, 2020
The bactericidal/permeability increasing protein (BPI) has an important function of nonspecific killing of Gram-negative bacteria. In this study, qPCR was used to detect the expression of the BPI gene in twelve tissues of Meishan piglets from birth to ...
Chao-hui DAI, Yue CAO, Zhong-cheng GAO, Guo-qiang ZHU, Sheng-long WU, Wen-bin BAO   +5 more
doaj   +1 more source

All-Trans Retinoic Acid Attenuates Transmissible Gastroenteritis Virus-Induced Apoptosis in IPEC-J2 Cells via Inhibiting ROS-Mediated P₃₈MAPK Signaling Pathway

Antioxidants, 2022
Transmissible gastroenteritis virus (TGEV) can cause diarrhea, dehydration, and high mortality in piglets, which is closely related to intestinal epithelial cell apoptosis caused by TGEV infection.
Junning Pu, Daiwen Chen, Gang Tian, Jun He, Zhiqing Huang, Ping Zheng, Xiangbing Mao, Jie Yu, Junqiu Luo, Yuheng Luo, Hui Yan, Bing Yu   +11 more
doaj   +1 more source