Results 1 to 10 of about 68,416 (116)
Roles of the Endogenous Lunapark Protein during Flavivirus Replication
Viruses, 2021 The endoplasmic reticulum (ER) of eukaryotic cells is a dynamic organelle, which undergoes continuous remodeling. At the three-way tubular junctions of the ER, the lunapark (LNP) protein acts as a membrane remodeling factor to stabilize these highly ...
Pham-Tue-Hung Tran +3 more
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Scientific Reports, 2022 The inflammasome-associated proteins caspase-1, caspase-4 and NLRP3 have been emphasised to be essential in the host cell response during urinary tract infection (UTI) by regulating IL-1β release.
Anna Lindblad +3 more
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Scientific Reports, 2022 Uropathogenic Escherichia coli (UPEC) may undergo a cyclic cascade of morphological alterations that are believed to enhance the potential of UPEC to evade host responses and re-infect host cell.
Katarina Persson +4 more
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A detailed molecular network map and model of the NLRP3 inflammasome
Frontiers in Immunology, 2023 The NLRP3 inflammasome is a key regulator of inflammation that responds to a broad range of stimuli. The exact mechanism of activation has not been determined, but there is a consensus on cellular potassium efflux as a major common denominator.
Marcus Krantz +7 more
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The Sterile Inflammatory Response [PDF]
Annual Review of Immunology, 2010 The acute inflammatory response is a double-edged sword. On the one hand, it plays a key role in initial host defense, particularly against many infections. On the other hand, its aim is imprecise, and as a consequence, when it is drawn into battle, it can cause collateral damage in tissues.
Kenneth L, Rock +3 more
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Inflammatory response and the endothelium [PDF]
Thrombosis Research, 2004 Antiphospholipid-mediated endothelium perturbation plays a role in antiphospholipid syndrome (APS)-associated vasculopathy. Antiphospholipid antibodies activate endothelium both in vitro and in vivo experimental models by inducing a pro-inflammatory/-coagulant phenotype; the antibodies recognize beta2 glycoprotein I (beta2GPI) on human endothelial ...
P.L. Meroni +11 more
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Frontiers in Psychiatry, 2021 Mental disorders are heterogeneous and psychiatric comorbidities are common. Previous studies have suggested a link between inflammation and mental disorders.
Ulrika Hylén +14 more
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Revealing new tick-borne encephalitis virus foci by screening antibodies in sheep milk
Parasites & Vectors, 2020 Background Tick distribution in Sweden has increased in recent years, with the prevalence of ticks predicted to spread towards the northern parts of the country, thus increasing the risk of tick-borne zoonoses in new regions. Tick-borne encephalitis (TBE)
Amélie Wallenhammar +8 more
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Lower activation of caspase-1 by Staphylococcus epidermidis isolated from prosthetic joint infections compared to commensals [PDF]
Journal of Bone and Joint Infection, 2018 Nosocomial sequence types of Staphylococcus epidermidis dominate in prosthetic joint infections. We examined caspase-1 activation in human neutrophils after incubation with Staphylococcus epidermidis isolated from prosthetic joint infections and normal ...
E. Månsson +8 more
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Scientific Reports, 2020 The NLRP3 inflammasome and IL-1β have recently been linked to the severity of uropathogenic Escherichia coli (UPEC)-mediated urinary tract infection (UTI).
Isak Demirel +5 more
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