Results 21 to 30 of about 68,515 (215)

INFLAMMATORY RESPONSES AND MEDIATORS

Surgical Clinics of North America, 2000
The host response to injury is usually appropriate in degree and is self-limited. In more severe injury, the host response may persist inappropriately, leading to SIRS and MODS and possibly multiple organ failure. The initial response to injury is mediated primarily by norepinephrine, and is directed toward preservation of circulation to the heart and ...
P K, Kim, C S, Deutschman
openaire   +2 more sources

Activation of the NLRP3 Inflammasome Pathway by Uropathogenic Escherichia coli Is Virulence Factor-Dependent and Influences Colonization of Bladder Epithelial Cells

Frontiers in Cellular and Infection Microbiology, 2018
The NLRP3 inflammasome and IL-1β release have recently been suggested to be important for the progression of urinary tract infection (UTI). However, much is still unknown regarding the interaction of UPEC and the NLRP3 inflammasome.
Isak Demirel, Isak Demirel, Alexander Persson, Alexander Persson, Annelie Brauner, Eva Särndahl, Eva Särndahl, Robert Kruse, Robert Kruse, Robert Kruse, Katarina Persson, Katarina Persson   +11 more
doaj   +1 more source

Plasma perfluoroalkyls are associated with decreased levels of proteomic inflammatory markers in a cross-sectional study of an elderly population

Environment International, 2020
Perfluoroalkyl substances (PFAS) have been linked to immunotoxicity in experimental studies. Although PFAS exposure is associated with altered immune response in epidemiological studies of children, it is less known whether this is observed also in ...
S. Salihovic, L. Lind, A. Larsson, P.M. Lind   +3 more
doaj   +1 more source

Inflammatory responses to parasites

Parasitology, 1987
The patients we are concerned about in tropical medicine are unfortunately affected by a wide range of conditions, not only those seen and studied extensively in the West, such as cancer, cardiovascular diseases and viral or bacterial infections, but also the major protozoan and metazoan conditions – the parasitic diseases.
C D, Mackenzie, A J, Gatrill, A J, Luty, D G, Manyasi, C, Moore, G, Sayers, S, Sulaiman   +6 more
openaire   +2 more sources

The inflammatory response in sepsis [PDF]

Trends in Immunology, 2013
The pathophysiology of sepsis and its accompanying systemic inflammatory response syndrome (SIRS) and the events that lead to multiorgan failure and death are poorly understood. It is known that, in septic humans and rodents, the development of SIRS is associated with a loss of the redox balance, but SIRS can also develop in noninfectious states.
Markus, Bosmann, Peter A, Ward
openaire   +2 more sources

Effects of a Paediatric Antimicrobial Stewardship Program on Antimicrobial Use and Quality of Prescriptions in Patients with Appendix-Related Intraabdominal Infections

Antibiotics, 2020
The effectiveness of antimicrobial stewardship programs (ASP) in reducing antimicrobial use (AU) in children has been proved. Many interventions have been described suitable for different institution sizes, priorities, and patients, with surgical wards ...
Sílvia Simó, Eneritz Velasco-Arnaiz, María Ríos-Barnés, María Goretti López-Ramos, Manuel Monsonís, Mireia Urrea-Ayala, Iolanda Jordan, Ricard Casadevall-Llandrich, Daniel Ormazábal-Kirchner, Daniel Cuadras-Pallejà, Xavier Tarrado, Jordi Prat, Emília Sánchez, Antoni Noguera-Julian, Clàudia Fortuny   +14 more
doaj   +1 more source

Transient Expression of Flavivirus Structural Proteins in Nicotiana benthamiana

Vaccines, 2022
Flaviviruses are a threat to public health and can cause major disease outbreaks. Tick-borne encephalitis (TBE) is caused by a flavivirus, and it is one of the most important causes of viral encephalitis in Europe and is on the rise in Sweden.
Naveed Asghar, Wessam Melik, Katrine M. Paulsen, Bendikte N. Pedersen, Erik G. Bø-Granquist, Rose Vikse, Snorre Stuen, Sören Andersson, Åke Strid, Åshild K. Andreassen, Magnus Johansson   +10 more
doaj   +1 more source

A Novel Nanosafety Approach Using Cell Painting, Metabolomics, and Lipidomics Captures the Cellular and Molecular Phenotypes Induced by the Unintentionally Formed Metal-Based (Nano)Particles

Cells, 2023
Additive manufacturing (AM) or industrial 3D printing uses cutting-edge technologies and materials to produce a variety of complex products. However, the effects of the unintentionally emitted AM (nano)particles (AMPs) on human cells following inhalation,
Andi Alijagic, Nikolai Scherbak, Oleksandr Kotlyar, Patrik Karlsson, Xuying Wang, Inger Odnevall, Oldřich Benada, Ali Amiryousefi, Lena Andersson, Alexander Persson, Jenny Felth, Henrik Andersson, Maria Larsson, Alexander Hedbrant, Samira Salihovic, Tuulia Hyötyläinen, Dirk Repsilber, Eva Särndahl, Magnus Engwall   +18 more
doaj   +1 more source

Estradiol Alters the Virulence Traits of Uropathogenic Escherichia coli

Frontiers in Microbiology, 2021
Uropathogenic Escherichia coli (UPEC) is the most common bacteria to cause urinary tract infection (UTI). Postmenopausal women have an increased risk of recurrent UTI. This is partly explained by estrogenic effects on host defenses against UTI.
Ulrik Engelsöy, Maria A. Svensson, Maria A. Svensson, Isak Demirel, Isak Demirel   +4 more
doaj   +1 more source

Transcriptional Alterations of Virulence-Associated Genes in Extended Spectrum Beta-Lactamase (ESBL)-Producing Uropathogenic Escherichia coli during Morphologic Transitions Induced by Ineffective Antibiotics

Frontiers in Microbiology, 2017
It is known that an ineffective antibiotic treatment can induce morphological shifts in uropathogenic Escherichia coli (UPEC) but the virulence properties during these shifts remain to be studied.
Isak Demirel, Isak Demirel, Ignacio Rangel, Ignacio Rangel, Ulrika Petersson, Katarina Persson, Katarina Persson, Robert Kruse, Robert Kruse   +8 more
doaj   +1 more source