Microorganisms, 2020 Kunjin virus (KUNV) is an attenuated strain of the severe neurotropic West Nile virus (WNV). The virus has a single-strand positive-sense RNA genome that encodes a polyprotein.
Pham-Tue-Hung Tran +7 more
doaj +1 more source
NLRP3 inflammasome as a sensor of micro- and nanoplastics immunotoxicity
Frontiers in Immunology, 2023 Micro- and nanoplastics (MNPs) are emerging pollutants with scarcely investigated effects on human innate immunity. If they follow a similar course of action as other, more thoroughly investigated particulates, MNPs may penetrate epithelial barriers ...
Andi Alijagic +10 more
doaj +1 more source
From bench to bedside: Calprotectin (S100A8/S100A9) as a biomarker in rheumatoid arthritis
Frontiers in Immunology, 2022 S100A9/S100A8 (calprotectin), a member of the S100 protein family, has been shown to play a pivotal role in innate immunity activation. Calprotectin plays a critical role in the pathogenesis of rheumatoid arthritis (RA), as it triggers chemotaxis ...
José Inciarte-Mundo +3 more
doaj +1 more source
The influence of surface morphology and wettability on the inflammatory response against poly(L-lactic acid): A semi-quantitative study with monoclonal antibodies [PDF]
, 1995 In this study, the influence of surface morphology and wettability of both degradable and nondegradable polymer films on the inflammatory response after subcutaneous implantation in the rat was investigated.
Baier +46 more
core +3 more sources
Fetal skin as a pro-inflammatory organ: Evidence from a primate model of chorioamnionitis. [PDF]
, 2017 BackgroundIntrauterine infection is a primary cause of preterm birth and fetal injury. The pro-inflammatory role of the fetal skin in the setting of intrauterine infection remains poorly characterized. Whether or not inflammation of the fetal skin occurs
Boonkasidecha, Suppawat +4 more
core +3 more sources
Nrf2 deficiency influences susceptibility to steroid resistance via HDAC2 reduction [PDF]
, 2010 Abnormal lung inflammation and oxidant burden are associated with a significant reduction in histone deacetylase 2 (HDAC2) abundance and steroid resistance.
Adenuga +33 more
core +1 more source
Frontiers in Toxicology, 2022 Additive manufacturing (AM) or industrial three-dimensional (3D) printing drives a new spectrum of design and production possibilities; pushing the boundaries both in the application by production of sophisticated products as well as the development of ...
Andi Alijagic +18 more
doaj +1 more source
Microarray analyses demonstrate the involvement of type i interferons in psoriasiform pathology development in D6-deficient mice [PDF]
, 2013 The inflammatory response is normally limited by mechanisms regulating its resolution. In the absence of resolution, inflammatory pathologies can emerge, resulting in substantial morbidity and mortality.
Baldwin, H.M. +9 more
core +1 more source
Lung inflammatory responses [PDF]
Veterinary Research, 2006 Inflammation is an important manifestation of respiratory disease in domestic animals. The respiratory system is mucosal in nature and has specific defense mechanisms used to control invasion by microbes and environmental elements. Inflammation can be beneficial or detrimental to the host.
openaire +3 more sources
Inflammation-induced DNA damage and damage-induced inflammation: a vicious cycle [PDF]
, 2014 Inflammation is the ultimate response to the constant challenges of the immune system by microbes, irritants or injury. The inflammatory cascade initiates with the recognition of microorganism-derived pathogen associated molecular patterns (PAMPs) and ...
Abe +100 more
core +1 more source